The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.
Poly(dA:dT) tracts: major determinants of nucleosome organization
Open accessAbstract
Summary Homopolymeric stretches of deoxyadenosine nucleotides (A’s) on one strand of double stranded DNA, referred to as poly(dA:dT) tracts or A-tracts, are overabundant in eukaryotic genomes. They have unusual structural, dynamic, and mechanical properties, and may resist sharp bending. Such unusual material properties, together with their overabundance in eukaryotes, raised the possibility that poly(dA:dT) tracts might function in eukaryotes to influence the organization of nucleosomes at many genomic regions. Recent genome-wide studies strongly confirm these ideas and suggest that these tracts play major roles in chromatin organization and genome function. Here we review what is known about poly(dA:dT) tracts and how they work.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
Kornberg, R. D., & Lorch, Y. (1999) · Cell · doi:10.1016/s0092-8674(00)81958-3 · Cited by 1,830
The structure of DNA in the nucleosome core
Richmond, T. J., & Davey, C. A. (2003) · Nature · doi:10.1038/nature01595 · Cited by 1,286
The DNA-encoded nucleosome organization of a eukaryotic genome
Kaplan, N., Moore, I. K., Fondufe-Mittendorf, Y., Gossett, A. J., Tillo, D., Field, Y., LeProust, E. M., Hughes, T. R., Lieb, J. D., Widom, J., et al. (2009) · Nature · doi:10.1038/nature07667 · Cited by 1,194
Self-citationGenome-Scale Identification of Nucleosome Positions in S. cerevisiae
Yuan, G.-C., Liu, Y.-J., Dion, M. F., Slack, M. D., Wu, L. F., Altschuler, S. J., & Rando, O. J. (2005) · Science · doi:10.1126/science.1112178 · Cited by 1,139
DNA sequence-dependent deformability deduced from protein–DNA crystal complexes
Olson, W. K., Gorin, A. A., Lu, X.-J., Hock, L. M., & Zhurkin, V. B. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.19.11163 · Cited by 1,038
The structure of an oligo(dA)·oligo(dT) tract and its biological implications
Nelson, H. C. M., Finch, J. T., Luisi, B. F., & Klug, A. (1987) · Nature · doi:10.1038/330221a0 · Cited by 979
A high-resolution atlas of nucleosome occupancy in yeast
Lee, W., Tillo, D., Bray, N., Morse, R. H., Davis, R. W., Hughes, T. R., & Nislow, C. (2007) · Nature Genetics · doi:10.1038/ng2117 · Cited by 829
A barrier nucleosome model for statistical positioning of nucleosomes throughout the yeast genome
Mavrich, T. N., Ioshikhes, I. P., Venters, B. J., Jiang, C., Tomsho, L. P., Qi, J., Schuster, S. C., Albert, I., & Pugh, B. F. (2008) · Genome Research · doi:10.1101/gr.078261.108 · Cited by 672
Struhl, K. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.24.8419 · Cited by 501
Distinct Modes of Regulation by Chromatin Encoded through Nucleosome Positioning Signals
Field, Y., Kaplan, N., Fondufe-Mittendorf, Y., Moore, I. K., Sharon, E., Lubling, Y., Widom, J., & Segal, E. (2008) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000216 · Cited by 457
Self-citation
Cited by
The role of DNA shape in protein–DNA recognition
Rohs, R., West, S. M., Sosinsky, A., Liu, P., Mann, R. S., & Honig, B. (2009) · Nature · doi:10.1038/nature08473 · Cited by 1,096
Determinants of nucleosome positioning
Struhl, K., & Segal, E. (2013) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2506 · Cited by 686
Self-citationRecombination centres and the orchestration of V(D)J recombination
Schatz, D. G., & Ji, Y. (2011) · Nature Reviews Immunology · doi:10.1038/nri2941 · Cited by 658
A map of nucleosome positions in yeast at base-pair resolution
Brogaard, K., Xi, L., Wang, J.-P., & Widom, J. (2012) · Nature · doi:10.1038/nature11142 · Cited by 462
Self-citationSharon, E., Kalma, Y., Sharp, A., Raveh-Sadka, T., Levo, M., Zeevi, D., Keren, L., Yakhini, Z., Weinberger, A., & Segal, E. (2012) · Nature Biotechnology · doi:10.1038/nbt.2205 · Cited by 457
Self-citation
Metadata
- Authors
- Segal, E., & Widom, J.
- Venue
- Current Opinion in Structural Biology
- Publisher
- Elsevier BV
- Published
- 2009-02
- Volume
- 19
- Issue
- 1
- Pages
- 65-71
- ISSN
- 0959-440X (ISSN-L)
- OpenAlex
- W1996065618
- Cited by
- 419
- References
- 44
- FWCI
- 2.11
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Poly(dA:dT) tracts: major determinants of nucleosome organization. https://app.cochat.ai/papers/10.1016/j.sbi.2009.01.004
- The paper
- Segal, E., & Widom, J. (2009). Poly(dA:dT) tracts: major determinants of nucleosome organization. Current Opinion in Structural Biology. https://doi.org/10.1016/j.sbi.2009.01.004
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
