Fragile X mental retardation protein levels are decreased in major psychiatric disorders
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Post mortem studies have shown that FMRP, the protein missing or deficient in FXS, is also deficient in the brain in patients with idiopathic ASD without a fragile X mutation.
“In addition, post mortem studies have shown that FMRP, the protein that is missing or deficient in FXS, is also deficient in the brain in patients with idiopathic ASD without a fragile X mutation [104, 105].”
From An Update on Psychopharmacological Treatment of Autism Spectrum Disorder (2022) · cites this paper as [104]
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References 10 · Cited by 69
Research works printed but not linked: 1
- Fatemi SH Folsom TD 2010b FMRP is reduced in the cerebella of subjects with autism Iranaian J Psychiatr Behav Neurosci in press
- Authors
- Fatemi, S. H., Kneeland, R. E., Liesch, S. B., & Folsom, T. D.
- Affiliations
- University of Minnesota (US)
- Corresponding author
- Fatemi, S. Hossein
- ORCID
- Fatemi, S. Hossein
- Venue
- Schizophrenia Research
- Publisher
- Elsevier BV
- Published
- 2010-12
- Volume
- 124
- Issue
- 1-3
- Pages
- 246-247
- ISSN
- 0920-9964 (ISSN-L)
- PMC
- PMC2981618
- OpenAlex
- W2043029511
- Cited by
- 69
- References
- 10
- Citations by year
- 2025: 2 · 2024: 4 · 2023: 1 · 2022: 4 · 2021: 2 · 2020: 3 · 2019: 4 · 2018: 5 · 2017: 6 · 2016: 3 · 2015: 6 · 2014: 6 · 2013: 8 · 2012: 3
- FWCI
- 3.96
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Schizophrenia Research (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R01MH086000)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Retinal Development and Disorders
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Keywords
- FMRP
- MeSH terms
- Actins, Bipolar Disorder, Cerebellum, Depressive Disorder, Major, Major Depressive Disorder, Humans, Postmortem Changes, Schizophrenia, Blotting, Western, Fragile X Mental Retardation Protein, Fragile X Messenger Ribonucleoprotein 1
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