The nature and timing of social deficits in child and adolescent offspring of parents with schizophrenia: preliminary evidence for precursors of negative symptoms
Open accessAbstract
Children with social dysfunction and a first-degree relative with schizophrenia are at elevated risk for schizophrenia; however, the nature of this dysfunction is unclear. It was hypothesized that familial high-risk (HR) children and adolescents (n=17) would have social skill deficits relative to healthy controls (HC; n=35). HR participants had a bimodal distribution of social skill scores (47% excellent; 53% poor). HR participants had worse social skills, assertion and empathy scores, suggesting possible developmental precursors to the social amotivation domain of negative symptoms. Characterizing HR children's social deficits could assist identification of those at risk for schizophrenia.
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Children at familial risk for developing psychosis present with poor social skills at all stages of development.
“children at familial risk for developing psychosis present with poor social skills at all stages of development (182).”
From A transdiagnostic perspective on social anhedonia (2019) · cites this paper as [182]
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References 19 · Cited by 14
- Authors
- Horton, L. E., Smith, A. A., & Haas, G. L.
- Affiliations
- University of Pittsburgh Medical Center (US)
- VA Pittsburgh Healthcare System (US)
- Corresponding author
- Horton, Leslie E.
- Venue
- Schizophrenia Research
- Publisher
- Elsevier BV
- Published
- 2014-10
- Volume
- 159
- Issue
- 1
- Pages
- 27-30
- ISSN
- 0920-9964 (ISSN-L)
- PMC
- PMC4243614
- OpenAlex
- W2137103219
- Cited by
- 14
- References
- 19
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 2 · 2022: 3 · 2021: 1 · 2020: 1 · 2019: 2 · 2018: 1 · 2017: 1
- FWCI
- 0.25
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Schizophrenia Research (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- NARSAD Independent Investigator (1098)
- Department of Psychiatry of the University of Pittsburgh School of Medicine
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Keywords
- schizophrenia
- MeSH terms
- Adolescent, Child, Child, Preschool, Female, Humans, Male, Parents, Psychiatric Status Rating Scales, Schizophrenia, Social Behavior Disorders, Child of Impaired Parents, Age of Onset, Young Adult, Social Skills
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