Peripubertal treatment with cannabidiol prevents the emergence of psychosis in an animal model of schizophrenia
Abstract
Fed Univ Sao Paulo UNIFESP EPM, Dept Psychiat, LiNC Interdisciplinary Lab Clin Neurosci, Sao Paulo, Brazil
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Peripubertal treatment with CBD inhibited the development of hyperlocomotion induced by prenatal treatment with poly I:C.
“Interestingly, in promising a recent study we found that peripubertal treatment with CBD inhibited the development of hyperlocomotion induced by prenatal treatment with poly I:C, indicating that this cannabinoid may have long-lasting properties of a peripubertal treatment as an intervention to prevent psychosis exhibited in the adulthood (72).”
From Translational investigation of the therapeutic potential of Cannabidiol (CBD): Toward a new age (2018) · cites this paper as [72]
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References 8 · Cited by 26
- Authors
- Peres, F. F., Diana, M. C., Suiama, M. A., Justi, V., Almeida, V., Bressan, R. A., Zuardi, A. W., Hallak, J. E., Crippa, J. A., & Abilio, V. C.
- Affiliations
- Universidade Federal de São Paulo (BR)
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (BR)
- Corresponding author
- Peres, F.F.
- Venue
- Schizophrenia Research
- Publisher
- Elsevier BV
- Published
- 2016-04
- Volume
- 172
- Issue
- 1-3
- Pages
- 220-221
- ISSN
- 0920-9964 (ISSN-L)
- OpenAlex
- W2266843423
- Cited by
- 26
- References
- 8
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2022: 1 · 2021: 2 · 2020: 6 · 2019: 3 · 2018: 6 · 2017: 2 · 2016: 2
- FWCI
- 3.50
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Schizophrenia Research (publishedVersion)
- PubMed (publishedVersion)
- UNIFESP Institutional Repository (Universidade Federal de São Paulo) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology › Cannabis and Cannabinoid Research
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Clinical Psychology › Psychedelics and Drug Studies
- Keywords
- cannabidiol, psychosis prevention
- MeSH terms
- Aging, Animals, Cannabidiol, Disease Models, Animal, Exploratory Behavior, Mice, Inbred C57BL, Motor Activity, Poly I-C, Psychological Tests, Psychotic Disorders, Schizophrenia, Schizophrenic Psychology, Social Behavior, Antipsychotic Agents, Treatment Outcome
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