The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Carcinogenic polycyclic aromatic hydrocarbons in umbilical cord blood of human neonates from Guiyu, China
Abstract
Unregulated electronic-waste recycling results in serious environmental pollution of polycyclic aromatic hydrocarbons (PAHs) in Guiyu, China. We evaluated the body burden of seven carcinogenic PAHs and potential health risks for neonates. Umbilical cord blood (UCB) samples were collected from Guiyu (n=103), and the control area of Chaonan (n=80), China. PAHs in UCB were determined by gas chromatography/mass spectrometry. The median ∑7c-PAH concentration was 108.05 ppb in UCB samples from Guiyu, vs. 79.36 ppb in samples from Chaonan. Residence in Guiyu and longer cooking time of food during the gestation period were significant factors contributing to the ∑7c-PAH level. Benzo[a]anthracene (BaA), chrysene (Chr), and benzo[a]pyrene (BaP) were found to correlate with reduced neonatal height and gestational age. Infants experiencing adverse birth outcomes, on the whole, displayed higher BaA, Chr, and BaP levels compared to those with normal outcomes. We conclude that maternal PAH exposure results in fetal accumulation of toxic PAHs, and that such prenatal exposure correlates with adverse effects on neonatal health.
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“Advances in bioanalytical methods have now revealed that PAHs and their metabolites can be found in the blood of adults,24, 25, 26, 27 children28, 29 and neonates,26, 30 as well as in urine18, 31, 32, 33 and maternal milk.26”
From The impact of airborne pollution on skin (2019) · cites this paper as [30]
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Cites
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Boström, C.-E., Gerde, P., Hanberg, A., Jernström, B., Johansson, C., Kyrklund, T., Rannug, A., Törnqvist, M., Victorin, K., & Westerholm, R. N. (2002) · Environmental Health Perspectives · doi:10.1289/ehp.02110s3451 · Cited by 848
Export of toxic chemicals – A review of the case of uncontrolled electronic-waste recycling
Wong, M. H., Wu, S., Deng, W., Yu, X., Luo, Q., Leung, A. O. W., Wong, C. S. C., Luksemburg, W. J., & Wong, A. S. (2007) · Environmental Pollution · doi:10.1016/j.envpol.2007.01.044 · Cited by 785
Ambient Air Pollution and Pregnancy Outcomes: A Review of the Literature
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The Impact of Polycyclic Aromatic Hydrocarbons and Fine Particles on Pregnancy Outcome
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Research works printed but not linked: 2
- Fan R. Preliminary study of urinary PAHs metabolites for students in Pearl River Delta and occupational population in Guiyu-an electronic waste recycling site. Doctoral dissertation, Guangzhou: Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, 2007.
- IARC, 1984, Monographs programme on the evaluation of the carcinogenic risk of chemicals to humans: polynuclear aromatic compounds, IARC Monogr Eval Carcinog Risks Hum, 34, 101
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Sorted by citations
Health consequences of exposure to e-waste: a systematic review
Grant, K., Goldizen, F. C., Sly, P. D., Bruné, M., Neira, M., van den Berg, M., & Norman, R. E. (2013) · The Lancet Global Health · doi:10.1016/s2214-109x(13)70101-3 · Cited by 811
Perkins, D. N., Bruné, M., Nxele, T., & Sly, P. D. (2014) · Annals of Global Health · doi:10.1016/j.aogh.2014.10.001 · Cited by 656
Removal of polycyclic aromatic hydrocarbons in aqueous environment by chemical treatments: A review
Rubio-Clemente, A., Torres-Palma, R. A., & Peñuela, G. A. (2014) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2013.12.126 · Cited by 326
Ahirwar, R., & Tripathi, A. K. (2020) · Environmental Nanotechnology Monitoring & Management · doi:10.1016/j.enmm.2020.100409 · Cited by 317
A review on human health consequences of metals exposure to e-waste in China
Song, Q., & Li, J. (2014) · Environmental Pollution · doi:10.1016/j.envpol.2014.11.004 · Cited by 252
Metadata
- Authors
- Guo, Y., Huo, X., Wu, K., Liu, J., Zhang, Y., & Xu, X.
- Affiliations
- Shantou University (CN)
- Corresponding author
- Xu, Xijin
- Venue
- Science of The Total Environment
- Publisher
- Elsevier BV
- Published
- 2012-06
- Volume
- 427-428
- Pages
- 35-40
- ISSN
- 0048-9697 (ISSN-L)
- OpenAlex
- W2020554241
- Cited by
- 133
- References
- 43
- Citations by year
- 2026: 9 · 2025: 5 · 2024: 9 · 2023: 8 · 2022: 11 · 2021: 16 · 2020: 9 · 2019: 9 · 2018: 10 · 2017: 11 · 2016: 10 · 2015: 6 · 2014: 8 · 2013: 12
- FWCI
- 5.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Science of The Total Environment (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Toxic Organic Pollutants Impact
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Environmental Toxicology and Ecotoxicology
- Keywords
- polycyclic aromatic hydrocarbons, umbilical cord blood, neonates, Guiyu, e-waste recycling, benzo[a]pyrene, benz[a]anthracene, chrysene, birth outcomes, gestational age, environmental pollution
- MeSH terms
- Adult, China, Environmental Exposure, Environmental Pollutants, Female, Fetal Blood, Humans, Infant, Newborn, Male, Polycyclic Aromatic Hydrocarbons, Pregnancy, Maternal Exposure, Young Adult, Electronic Waste
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