Global occurrence and probabilistic environmental health hazard assessment of per- and polyfluoroalkyl substances (PFASs) in groundwater and surface waters
Open accessAbstract
Per- and polyfluoroalkyl substances (PFASs) have been used in consumer and military products since the 1950s but are increasingly scrutinized worldwide because of inherent chemical properties, environmental contamination, and risks to public health and the environment. The United States Environmental Protection Agency (USEPA) identified 24 PFASs of interest for further study and possible regulation. We examined 371 peer-reviewed studies published since 2001 to understand the occurrence and distribution of 24 priority PFASs in global surface waters and groundwater. We identified 77,541 and 16,246 data points for surface waters and groundwater, respectively, with total PFAS concentrations ranging from low pg/L to low mg/L levels. Most data were from Asia, Europe, and North America with some reports from Oceania. PFAS information from other geographic regions is lacking. PFASs levels are consistently higher in rivers and streams followed by lakes and reservoirs and then coastal and marine systems. When sufficient data were available, probabilistic environmental hazard assessments (PEHAs) were performed from environmental exposure distributions (EEDs) to identify potential exceedances of available guideline values for each compound by matrix, region, and aquatic system. Specifically, exceedances of USEPA drinking water lifetime health advisory levels were up to 74% for PFOS in groundwater from Oceania and 69% for PFOA in North American groundwater. Our findings support selection…
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Among water bodies without acute contamination sources, PFAS are more common in surface water than groundwater.
“Among water bodies without acute contamination sources, the PFAS content of surface water is much more extensively surveyed than that of groundwater, and PFAS are more common in surface water than groundwater (Munoz et al., 2017; Sims et al., 2022).”
From PFAS in Iowa drinking water sources: Chemical and geospatial patterns (2025) · cites this paper as Sims et al., 2022
Few studies have sought to characterize PFAS contamination profiles in public drinking water supplies that do not have a clear contamination source.
“Few studies have sought to characterize PFAS contamination profiles in public drinking water supplies that do not have a clear contamination source (Gobelius et al., 2018; Sims et al., 2022).”
From PFAS in Iowa drinking water sources: Chemical and geospatial patterns (2025) · cites this paper as Sims et al., 2022
Compared to a literature review groundwater dataset, both detection rates and concentrations in the UDB are lower than the global average.
“Compared to the groundwater dataset from a literature review [115], both the detection rates and concentrations in the UDB are lower than the global average.”
From Investigating the extent of PFAS contamination in the Upper Danube Basin across environmental compartments (2025) · cites this paper as [115]
Rivers are often the aquatic system most affected by PFAS contamination.
“Rivers are often the aquatic system most affected by PFAS contamination [115].”
From Investigating the extent of PFAS contamination in the Upper Danube Basin across environmental compartments (2025) · cites this paper as [115]
The summed concentrations of PFAS are influenced by differences in the inclusion of compounds and the methodological change from the simple additive approach in DWD (2020) to the toxicology-based evaluation in the proposed EQS (2022), which accounts for differences in PFAS toxicity.
“It is important to note that the summed concentrations of PFAS are influenced by differences in the inclusion of the compound and the methodological change from the simple additive approach in DWD (2020) to the toxicology-based evaluation in the proposed EQS (2022), which accounts for differences in PFAS toxicity [115].”
From Investigating the extent of PFAS contamination in the Upper Danube Basin across environmental compartments (2025) · cites this paper as [115]
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References 85 · Cited by 214
- Authors
- Sims, J. L., Stroski, K. M., Kim, S., Killeen, G., Ehalt, R., Simcik, M. F., & Brooks, B. W.
- Affiliations
- Baylor University (US)
- University of Minnesota (US)
- Corresponding author
- Brooks, Bryan W.
- Venue
- Science of The Total Environment
- Publisher
- Elsevier BV
- Published
- 2022-04
- Volume
- 816
- Pages
- 151535
- ISSN
- 0048-9697 (ISSN-L)
- OpenAlex
- W3211761789
- Cited by
- 214
- References
- 85
- Citations by year
- 2026: 36 · 2025: 70 · 2024: 64 · 2023: 33 · 2022: 11
- FWCI
- 2.00
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (am, 316 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Locations
- The Science of The Total Environment (acceptedVersion)
- PubMed (publishedVersion)
- Funders
- Strategic Environmental Research and Development Program (W912HQ19C0050, ER19-1350)
- Topics
- Physical Sciences › Environmental Science › Environmental Chemistry › Per- and polyfluoroalkyl substances research
- Physical Sciences › Environmental Science › Water Science and Technology › Fluoride Effects and Removal
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Chemical Analysis and Environmental Impact
- Keywords
- per- and polyfluoroalkyl substances, groundwater contamination, surface water contamination, PFOS, perfluorooctanoic acid, aquatic ecosystems
- MeSH terms
- Environmental Health, Environmental Monitoring, Fluorocarbons, Water Pollutants, Chemical, Alkanesulfonic Acids, Groundwater, Drinking Water
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