Obstructive sleep apnea, cognition and Alzheimer's disease: A systematic review integrating three decades of multidisciplinary research

Bubu, Omonigho M.; Andrade, Andreia G.; Umasabor-Bubu, Ogie Q.; Hogan, Megan M.; Turner, Arlener D.; de Leon, Mony J.; Ogedegbe, Gbenga; Ayappa, Indu; Jean-Louis G, Girardin; Jackson, Melinda L.; Varga, Andrew W.; Osorio, Ricardo S.

doi:10.1016/j.smrv.2019.101250

Obstructive sleep apnea, cognition and Alzheimer's disease: A systematic review integrating three decades of multidisciplinary research

SUMMARY Increasing evidence links cognitive-decline and Alzheimer’s disease (AD) to various sleep disorders, including obstructive sleep apnea (OSA). With increasing age, there are substantial differences in OSA’s prevalence, associated comorbidities and phenotypic presentation. An important ques…