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A history of intragastric balloons
Abstract
The history of intragastric balloons (IGBs) began in 1985 with the Garren-Edwards Bubble. It was approved by the U.S. Food and Drug Administration (FDA) for temporary use as a weight loss device, but its manufacture was discontinued in 1988, and approval was withdrawn in 1992 because of significant complications and limited and recidivistic weight loss. A number of IGBs have appeared since that time, mostly originating in Europe or South America, but none has acquired FDA approval until recently; the ReShape Duo Integrated Dual Balloon System (ReShape Medical Inc., San Clemente, California) received FDA approval in August 2015. The conclusions of an important 1987 international conference on IGBs and the characteristics, effectiveness, and problems of most other IGBs are described in this text. The common purpose of these devices as preliminary interventions before gastric bariatric surgery and their favorable effects on this purpose are emphasized and may have played a key role in the FDA's change of outlook of the IGB.
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“Initially introduced in 1984, the first FDA-approved balloon, the Garren-Edwards Gastric Bubble (GEGB), was discontinued after seven years due to significant adverse effects, including gastric erosion, ulcers, small bowel obstruction, and inadequate weight reduction [68,69].”
From Impact of Bariatric Surgery and Endoscopic Therapies on Liver Health in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Review (2025) · cites this paper as [68]
In the citing paper
“APRI scores improved with EndoBarrier (45–55%) [102], POSE (31%) [68], and IGB (37.8%) [73].”
From Impact of Bariatric Surgery and Endoscopic Therapies on Liver Health in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Review (2025) · cites this paper as [68]
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Rojano‐Rodriguez, M., Rentería-Palomo, E., Reséndiz-Barragán, A. M., Salinas-Cornejo, G. D. L. Á., & Romero‐Loera, L. S. (2020) · Springer eBooks · doi:10.1007/978-3-030-27897-7_11
Obalon Intragastric Balloon System Overview
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[Intragastric balloon for weight reduction: rationale, benefits, risks and indications].
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DIAGNÓSTICOS E INTERVENÇÕES DE ENFERMAGE
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Metadata
- Authors
- Gleysteen, J. J.
- Affiliations
- University of Alabama at Birmingham (US)
- Corresponding author
- Gleysteen, John J.
- Venue
- Surgery for Obesity and Related Diseases
- Publisher
- Elsevier BV
- Published
- 2016-02
- Volume
- 12
- Issue
- 2
- Pages
- 430-435
- ISSN
- 1550-7289 (ISSN-L)
- OpenAlex
- W2186040095
- Cited by
- 113
- References
- 33
- Citations by year
- 2026: 6 · 2025: 10 · 2024: 5 · 2023: 15 · 2022: 12 · 2021: 13 · 2020: 15 · 2019: 8 · 2018: 14 · 2017: 12 · 2016: 3
- FWCI
- 9.03
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- Locations
- Surgery for Obesity and Related Diseases (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Medicine › Pharmacology (medical) › Pharmacology and Obesity Treatment
- Health Sciences › Medicine › Surgery › Body Contouring and Surgery
- Keywords
- intragastric balloon
- MeSH terms
- Humans, Obesity, Morbid, Weight Loss, Gastric Balloon, History, 20th Century, History, 21st Century
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.