Targeting HIF1α Eliminates Cancer Stem Cells in Hematological Malignancies

Wang, Yin, Liu, Yan, Malek, Sami N., Zheng, Pan, Liu, Yang·2011·Cell stem cell

Cited by (410)

Items 201–300 of 410

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  2. HIF1α-mediated transactivation of WTAP promotes AML cell proliferation via m6A-dependent stabilization of KDM4B mRNA
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  3. Role of HDAC3-miRNA-CAGE Network in Anti-Cancer Drug-Resistance
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  4. Targeting Leukemia Stem Cell-Niche Dynamics: A New Challenge in AML Treatment
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  5. Unlocking the Secrets of Cancer Stem Cells with γ-Secretase Inhibitors: A Novel Anticancer Strategy
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  6. The Complexity of the Tumor Microenvironment and Its Role in Acute Lymphoblastic Leukemia: Implications for Therapies
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  7. Role of nitric oxide in the maintenance of pluripotency and regulation of the hypoxia response in stem cells
    Amparo Beltrán-Povea · 2015 · World Journal of Stem Cells
  8. Effect of hypoxia-inducible factors in normal and leukemic stem cell regulation and their potential therapeutic impact
    Kevin Rouault‐Pierre, Ashley Hamilton, Dominique A. Bonnet · 2015 · Expert Opinion on Biological Therapy
  9. Novel strategies for targeting leukemia stem cells: sounding the death knell for blood cancer
    A. Chávez-González, Babak Bakhshinejad, Katayoon Pakravan, M. Guzman, S. Babashah · 2016 · Cellular Oncology
  10. Differential hypoxic regulation of the microRNA-146a/CXCR4 pathway in normal and leukemic monocytic cells: impact on response to chemotherapy
    Isabella Spinello, Maria Teresa Quaranta, Rosa Paolillo, Elvira Pelosi, Annamaria Cerio, Ernestina Saulle, F. L. Coco, Ugo Testa, Catherine Labbaye · 2015 · Haematologica
  11. HIF inhibitors for ischemic retinopathies and cancers: options beyond anti-VEGF therapies
    Saima Subhani, Divya Teja Vavilala, Mridul Mukherji · 2016 · Angiogenesis
  12. Characterization of gastric cancer stem-like molecular features, immune and pharmacogenomic landscapes
    Chen Wei, Mingkai Chen, Wenying Deng, Liangyu Bie, Yijie Ma, Chi Zhang, Kangdong Liu, Wei Shen, Shuyi Wang, Chaogang Yang et al. · 2021 · Briefings in Bioinformatics
  13. Evaluation of Anti-HIF and Anti-Angiogenic Properties of Honokiol for the Treatment of Ocular Neovascular Diseases
    Divya Teja Vavilala, V. K. Chaithanya Ponnaluri, D. Kanjilal, Mridul Mukherji · 2014 · PLoS ONE
  14. Small molecule inhibitors in acute myeloid leukemia: from the bench to the clinic
    Muneera Al-Hussaini, John F. DiPersio · 2014 · Expert Review of Hematology
  15. Targeting Leukemia Stem Cells: Which Pathways Drive Self-Renewal Activity in T-Cell Acute Lymphoblastic Leukemia?
    Miriam Belmonte, Catherine Hoofd, Andrew P. Weng, Vincenzo Giambra · 2016 · Current Oncology
  16. Gli1 expression in cancer stem-like cells predicts poor prognosis in patients with lung squamous cell carcinoma
    Yan Ru Cui, Chunai Cui, Zhaoting Yang, Wei-dong Ni, Yu Jin, Yanhua Xuan · 2017 · Experimental and Molecular Pathology
  17. HIF‐1α/Actl6a/H3K9ac axis is critical for pluripotency and lineage differentiation of human induced pluripotent stem cells
    Peng Cui, Ping Zhang, Yanmin Zhang, Lihua Sun, Guanghui Cui, Xin Guo, He Wang, Xiaowei Zhang, Yu Shi, Zhendong Yu · 2020 · The FASEB Journal
  18. Anaerobicizing into Pluripotency
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  19. Can immunotherapy specifically target acute myeloid leukemic stem cells?
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  20. Biology of the bone marrow microenvironment and myelodysplastic syndromes
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  22. Targeting the HIF-1α-IGFBP2 axis therapeutically reduces IGF1-AKT signaling and blocks the growth and metastasis of relapsed anaplastic Wilms tumor
    Yan Liu, Marie V. Nelson, Christopher M. Bailey, Peng Zhang, Pan Zheng, Jeffrey S. Dome, Yang Liu, Yin Wang · 2021 · Oncogene
  23. Essential role of PLD2 in hypoxia-induced stemness and therapy resistance in ovarian tumors
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  25. Evaluation of Curcumin, a Natural Product in Turmeric, on Burkitt Lymphoma and Acute Myeloid Leukemia Cancer Stem Cell Markers
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  27. Loss of miR-31-5p drives hematopoietic stem cell malignant transformation and restoration eliminates leukemia stem cells in mice
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  28. Extracellular-signal-regulated kinase 5 modulates the antioxidant response by transcriptionally controlling Sirtuin 1 expression in leukemic cells
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  29. A HIF-1 network reveals characteristics of epithelial-mesenchymal transition in acute promyelocytic leukemia
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  30. Radioresistance and Cancer Stem Cells: Survival of the Fittest
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  35. Noncanonical roles of p53 in cancer stemness and their implications in sarcomas
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  36. Meis1 supports leukemogenesis through stimulation of ribosomal biogenesis and Myc
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  37. Loss of HIF-1α accelerates murine FLT-3ITD-induced myeloproliferative neoplasia
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  38. Deferasirox selectively induces cell death in the clinically relevant population of leukemic CD34+CD38– cells through iron chelation, induction of ROS, and inhibition of HIF1α expression
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  39. Long Non-Coding RNA Taurine Upregulated Gene 1 Targets miR-185 to Regulate Cell Proliferation and Glycolysis in Acute Myeloid Leukemia Cells in vitro
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  41. Relevance of leukemic stem cells in acute myeloid leukemia: heterogeneity and influence on disease monitoring, prognosis and treatment design
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  42. Hypoxia-Like Signatures Induced by BCR-ABL Potentially Alter the Glutamine Uptake for Maintaining Oxidative Phosphorylation
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  43. Hypoxia inducible factor-1α regulates a pro-invasive phenotype in acute monocytic leukemia
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  44. Emetine induces chemosensitivity and reduces clonogenicity of acute myeloid leukemia cells
    Josep María Cornet-Masana, Daniel Moreno-Martínez, María Carmen Lara-Castillo, Meritxell Nomdedéu, Amaia Etxabe, Niccoló Tesi, Marta Pratcorona, Jordi Esteve, Ruth M. Risueño · 2016 · Oncotarget
  45. Cited2 in hematopoietic stem cell function
    Jinwei Du, Yu‐Chung Yang · 2013 · Current Opinion in Hematology
  46. The hypoxic microenvironment: A determinant of cancer stem cell evolution
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  47. Evaluating ivosidenib for the treatment of relapsed/refractory AML: design, development, and place in therapy
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  48. High-CLDN4 ESCC cells harbor stem-like properties and indicate for poor concurrent chemoradiation therapy response in esophageal squamous cell carcinoma
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  49. Iron removal enhances vitamin C-induced apoptosis and growth inhibition of K-562 leukemic cells
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  50. Synergistic binding of actinomycin D and echinomycin to DNA mismatch sites and their combined anti-tumour effects
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  51. Crosstalk between hypoxic cellular micro-environment and the immune system: a potential therapeutic target for infectious diseases
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  53. Hypoxia-Mediated Regulation of Stem Cell Fate
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  54. Hif-1α Deletion May Lead to Adverse Treatment Effect in a Mouse Model of MLL-AF9-Driven AML
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  55. Sustain, Adapt, and Overcome—Hypoxia Associated Changes in the Progression of Lymphatic Neoplasia
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  56. Hypoxic stress and hypoxia-inducible factors in leukemias
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  60. Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells
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