Targeting HIF1α Eliminates Cancer Stem Cells in Hematological Malignancies
Wang, Yin, Liu, Yan, Malek, Sami N., Zheng, Pan, Liu, Yang·2011·Cell stem cell
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Items 201–300 of 410
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- The Complexity of the Tumor Microenvironment and Its Role in Acute Lymphoblastic Leukemia: Implications for TherapiesCarolina Simioni, Ilaria Conti, Gabriele Varano · 2021 · Frontiers in Oncology
- Role of nitric oxide in the maintenance of pluripotency and regulation of the hypoxia response in stem cellsAmparo Beltrán-Povea · 2015 · World Journal of Stem Cells
- Effect of hypoxia-inducible factors in normal and leukemic stem cell regulation and their potential therapeutic impactKevin Rouault‐Pierre, Ashley Hamilton, Dominique A. Bonnet · 2015 · Expert Opinion on Biological Therapy
- Novel strategies for targeting leukemia stem cells: sounding the death knell for blood cancerA. Chávez-González, Babak Bakhshinejad, Katayoon Pakravan, M. Guzman, S. Babashah · 2016 · Cellular Oncology
- Differential hypoxic regulation of the microRNA-146a/CXCR4 pathway in normal and leukemic monocytic cells: impact on response to chemotherapyIsabella Spinello, Maria Teresa Quaranta, Rosa Paolillo, Elvira Pelosi, Annamaria Cerio, Ernestina Saulle, F. L. Coco, Ugo Testa, Catherine Labbaye · 2015 · Haematologica
- HIF inhibitors for ischemic retinopathies and cancers: options beyond anti-VEGF therapiesSaima Subhani, Divya Teja Vavilala, Mridul Mukherji · 2016 · Angiogenesis
- Characterization of gastric cancer stem-like molecular features, immune and pharmacogenomic landscapesChen Wei, Mingkai Chen, Wenying Deng, Liangyu Bie, Yijie Ma, Chi Zhang, Kangdong Liu, Wei Shen, Shuyi Wang, Chaogang Yang et al. · 2021 · Briefings in Bioinformatics
- Evaluation of Anti-HIF and Anti-Angiogenic Properties of Honokiol for the Treatment of Ocular Neovascular DiseasesDivya Teja Vavilala, V. K. Chaithanya Ponnaluri, D. Kanjilal, Mridul Mukherji · 2014 · PLoS ONE
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- Targeting Leukemia Stem Cells: Which Pathways Drive Self-Renewal Activity in T-Cell Acute Lymphoblastic Leukemia?Miriam Belmonte, Catherine Hoofd, Andrew P. Weng, Vincenzo Giambra · 2016 · Current Oncology
- Gli1 expression in cancer stem-like cells predicts poor prognosis in patients with lung squamous cell carcinomaYan Ru Cui, Chunai Cui, Zhaoting Yang, Wei-dong Ni, Yu Jin, Yanhua Xuan · 2017 · Experimental and Molecular Pathology
- HIF‐1α/Actl6a/H3K9ac axis is critical for pluripotency and lineage differentiation of human induced pluripotent stem cellsPeng Cui, Ping Zhang, Yanmin Zhang, Lihua Sun, Guanghui Cui, Xin Guo, He Wang, Xiaowei Zhang, Yu Shi, Zhendong Yu · 2020 · The FASEB Journal
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- Can immunotherapy specifically target acute myeloid leukemic stem cells?Sylvia Snauwaert, Bart Vandekerckhove, Tessa C. C. Kerre · 2013 · OncoImmunology
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- Targeting the HIF-1α-IGFBP2 axis therapeutically reduces IGF1-AKT signaling and blocks the growth and metastasis of relapsed anaplastic Wilms tumorYan Liu, Marie V. Nelson, Christopher M. Bailey, Peng Zhang, Pan Zheng, Jeffrey S. Dome, Yang Liu, Yin Wang · 2021 · Oncogene
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- Loss of miR-31-5p drives hematopoietic stem cell malignant transformation and restoration eliminates leukemia stem cells in miceBiying Zhu, Wenbin Zhong, Xiuye Cao, Guoping Pan, Meng‐Yang Xu, Jie Zheng, Huanzhao Chen, Xiaoqin Feng, Chengwei Luo, Chen Lu et al. · 2022 · Science Translational Medicine
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- Deferasirox selectively induces cell death in the clinically relevant population of leukemic CD34+CD38– cells through iron chelation, induction of ROS, and inhibition of HIF1α expressionSaar Shapira, Pia Raanani, Aladin Samara, Arnon Nagler, Ido Lubin, Nadir Arber, Galit Granot · 2018 · Experimental Hematology
- Long Non-Coding RNA Taurine Upregulated Gene 1 Targets miR-185 to Regulate Cell Proliferation and Glycolysis in Acute Myeloid Leukemia Cells in vitroWeide Zhang, Yuhua Liu, Jing Zhang · 2020 · OncoTargets and Therapy
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- Hypoxia-Like Signatures Induced by BCR-ABL Potentially Alter the Glutamine Uptake for Maintaining Oxidative PhosphorylationPallavi Sontakke, Katarzyna M. Koczula, Jennifer Jaques, Albertus T.J. Wierenga, Annet Z. Brouwers-Vos, Maurien G. M. Pruis, Ulrich L. Günther, Edo Vellenga, Jan Jacob Schuringa · 2016 · PLoS ONE
- Hypoxia inducible factor-1α regulates a pro-invasive phenotype in acute monocytic leukemiaJessica Migliavacca, Stefano Percio, Roberta Valsecchi, Elisabetta Ferrero, Antonello Enrico Spinelli, Maurilio Ponzoni, Cristina Tresoldi, Linda Pattini, Rosa Bernardi, Nadia Coltella · 2016 · Oncotarget
- Emetine induces chemosensitivity and reduces clonogenicity of acute myeloid leukemia cellsJosep María Cornet-Masana, Daniel Moreno-Martínez, María Carmen Lara-Castillo, Meritxell Nomdedéu, Amaia Etxabe, Niccoló Tesi, Marta Pratcorona, Jordi Esteve, Ruth M. Risueño · 2016 · Oncotarget
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- Iron removal enhances vitamin C-induced apoptosis and growth inhibition of K-562 leukemic cellsMitsuyo Tsuma-Kaneko, Masakazu Sawanobori, Shohei Kawakami, Tomoko Uno, Yoshihiko Nakamura, Makoto Onizuka, Kiyoshi Ando, Hiroshi Kawada · 2018 · Scientific Reports
- Synergistic binding of actinomycin D and echinomycin to DNA mismatch sites and their combined anti-tumour effectsRoshan Satange, Chih-Chun Chang, Long‐Yuan Li, Sheng‐Hao Lin, Stephen Neidle, Ming‐Hon Hou · 2023 · Nucleic Acids Research
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