Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation
Florian, Maria Carolina, Dörr, Karin, Niebel, Anja, Daria, Deidre, Schrezenmeier, Hubert, Rojewski, Markus, Filippi, Marie-Dominique, Hasenberg, Anja +4 more·2012·Cell Stem Cell
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- Cdc42 and aging of hematopoietic stem cellsHartmut Geiger, Yi Zheng · 2013 · Current Opinion in Hematology
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