The NAD+-Dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells

Ryall, James G., Dell’Orso, Stefania, Derfoul, Assia, Juan, Aster, Zare, Hossein, Feng, Xuesong, Clermont, Daphney, Koulnis, Miroslav +3 more·2015·Cell Stem Cell

Cited by (581)

Items 501–581 of 581

  1. The Effects of Exercise on LINE-1 Regulation
    Matthew A. Romero · 2019
  2. Adult Muscle Stem Cell Self-Renewal Induced by Endurance Exercise is Mediated by Inhibition of Mitochondrial Oxygen Consumption
    Phablo Abreu, Alicia Juliana Kowaltowski · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  3. Introduction to Protein Posttranslational Modifications (PTMs)
    Xiucong Bao · 2020 · Springer theses
  4. A CHCHD10 variant causing ALS elicits an unfolded protein response through the IRE1/XBP1 pathway
    Isabella R. Straub, Woranontee Weraarpachai, Eric A. Shoubridge · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  5. Muscle-secreted G-CSF as a metabolic niche factor ameliorates loss of muscle stem cell in aged mice
    Hu Li, Qian Chen, Changyin Li, Ran Zhong, Yixia Zhao, Qianying Zhang, Wei‐Min Tong, Dahai Zhu, Yong Zhang · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  6. Efeitos da suplementação de ribosídeo de nicotinamida sobre a UPR mitocondrial na musculatura esquelética e sobre a performance aeróbia de camundongos
    Bárbara Crisol · 2018
  7. Comprehensive Analyses of miRNA and DNA Methylation in 17beta-Estradiol Exposed Juvenile Rainbow Trout Skeletal Muscle
    Prasanthi P. Koganti · 2017
  8. ADP-ribose triggers neuronal ferroptosis by rewiring purine and pyrimidine metabolism
    Haoqi Ni, Yingying He, Peng Cui, Hebing Chen, Guoqing Lv, Huiyan Lei, Feng Wang, Qichuan Zhuge, Baodong Chen, Ling Liang et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  9. Crotonylation promotes human embryonic stem cell endodermal lineage differentiation and metabolic switch
    Zhou Songyang, Jingran Zhang, Guang W. Shi, Junjie Pang, Xing Quan Zhu, Wenbin Ma, Dan Liu · 2021 · Research Square
  10. The NAD+-Dependent Histone Deacetylase Sirtuin-2 is Upregulated during Myogenesis and Promotes the Differentiation of C2C12 Myoblasts
    David A. Stanton · 2017
  11. Regenerative nutrition and gut microbiota signaling in skeletal muscle metabolism: a concise systematic review
    Michelle Silva Rocha, Lorenna Lemos de Aquino, Clarice Paiva de Oliveira, Juliana Leite Salviano, Lucas Ramos Patrício, Thiago Rodrigues dos Santos, Vinícius Bezerra Lopes, Weyller Camargo Dias, Ágda Tamires da Silva Rodrigues, Idiberto José Zotarelli-Filho · 2022 · International Journal of Nutrology
  12. Faculty Opinions recommendation of Niche Cadherins Control the Quiescence-to-Activation Transition in Muscle Stem Cells.
    Dawn Cornelison · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  13. The Mechanism of Decline of Senescent Skeletal Muscle Satellite Cell Self-Renewal and Regenerative Proliferation: The Role of Heparan Sulfate-FGF-2--FGFR1-p38αMAPK Axis, Sprouty1, miR-1, miR-133 and miR-29a
    John Papaconstantinou · 2020 · Journal of Skeletal Muscle
  14. Inhibition of Type I PRMTs Reforms Muscle Stem Cell Identity Enhancing their Therapeutic Capacity
    Claudia Dominici, Oscar David Villarreal, Junio Dort, Émilie Heckel, Yu Chang Wang, Ioannis Ragoussis, Jean‐Sébastien Joyal, Nicolas A. Dumont, Stéphane Richard · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  15. Sports nutrology and gut microbiota
    Lucas Vasconcelos Lima Diniz · 2023 · International Journal of Nutrology
  16. Inhibition of Type I PRMTs Reforms Muscle Stem Cell Identity Enhancing their Therapeutic Capacity
    Claudia Dominici, Oscar Villareal, Junio Dort, Émilie Heckel, Yu Chang Wang, Ioannis Ragoussis, Jean‐Sébastien Joyal, Nicolas A. Dumont, Stéphane Richard · 2023 · eLife
  17. eLife Assessment: Inhibition of Type I PRMTs Reforms Muscle Stem Cell Identity Enhancing their Therapeutic Capacity
    Christopher P. Cardozo · 2023 · eLife
  18. Reviewer #1 (Public Review): Inhibition of Type I PRMTs Reforms Muscle Stem Cell Identity Enhancing their Therapeutic Capacity
    2023 · eLife
  19. Reviewer #2 (Public Review): Inhibition of Type I PRMTs Reforms Muscle Stem Cell Identity Enhancing their Therapeutic Capacity
    2023 · eLife
  20. Reviewer #3 (Public Review): Inhibition of Type I PRMTs Reforms Muscle Stem Cell Identity Enhancing their Therapeutic Capacity
    2023 · eLife
  21. Author Response: Inhibition of Type I PRMTs Reforms Muscle Stem Cell Identity Enhancing their Therapeutic Capacity
    Claudia Dominici, Oscar Villareal, Junio Dort, Émilie Heckel, Yu Chang Wang, Ioannis Ragoussis, Jean‐Sébastien Joyal, Nicolas A. Dumont, Stéphane Richard · 2023 · eLife
  22. Inhibition of Type I PRMTs Reforms Muscle Stem Cell Identity Enhancing their Therapeutic Capacity
    Claudia Dominici, Oscar David Villarreal, Junio Dort, Émilie Heckel, Yu Chang Wang, Ioannis Ragoussis, Jean‐Sébastien Joyal, Nicolas A. Dumont, Stéphane Richard · 2023 · eLife
  23. Inhibition of type I PRMTs reforms muscle stem cell identity enhancing their therapeutic capacity
    Claudia Dominici, Oscar David Villarreal, Junio Dort, Émilie Heckel, Yu Chang Wang, Ioannis Ragoussis, Jean‐Sébastien Joyal, Nicolas A. Dumont, Stéphane Richard · 2023 · eLife
  24. Körperliche Aktivität, Gesundheitszustand und Trainierbarkeit – genetische und epigenetische Aspekte
    Wolfgang Laube · 2023 · Springer eBooks
  25. GLUD1 dictates muscle stem cell differentiation by controlling mitochondrial glutamate levels
    Inés Soro-Arnáiz, Sarah Cherkaoui, Gillian Fitzgerald, Jing Zhang, Paola A. Gilardoni, Adhideb Ghosh, Ori Bar‐Nur, Evi Masschelein, Pierre Maechler, Nicola Zamboni et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  26. Additional file 2 of Crotonylation of GAPDH regulates human embryonic stem cell endodermal lineage differentiation and metabolic switch
    Jingran Zhang, Guang W. Shi, Junjie Pang, Xing Quan Zhu, Feng, Qingcai, Jie Na, Wenbin Ma, Dan Liu, Zhou Songyang · 2023 · Figshare
  27. NMR-based comparative metabolomics of quiescent muscle cells
    Gunjan Purohit, Akila Ramesh, Anant Bahadur Patel, Jyotsna Dhawan · 2024 · Journal of Biosciences
  28. Gut microbiota and skeletal muscle axis in sports performance through nutrological activation of irisin and microRNAs: a systematic review
    Hugo Menezes Lopes, Mateus Antunes Nogueira, Márcia Cavalheiro Alves, Ricardo de Oliveira Carvalho, Ana Claudia Santana Cano, Vittor Cândido Soares, Frederico Teixeira Izidorio, Juliana da Silva Pereira, Marília de Andrade Salvá, Thamyres Veras Alves · 2024 · International Journal of Nutrology
  29. Changes in protein fluxes and gene expression in non‐injured muscle tissue distant from an acute myotoxic injury in male mice
    Alec Bizieff, Maggie Cheng, Kelvin Chang, Hussein Mohammed, Naveed Ziari, Edna Nyangau, Mark D. Fitch, Marc K. Hellerstein · 2024 · The Journal of Physiology
  30. Glycolytic flux controls retinal progenitor cell differentiation via regulating Wnt signaling
    Joseph Hanna, Yacine Touahri, Alissa Pak, Lauren Belfiore, Edwin van Oosten, Luke Ajay David, Sisu Han, Yaroslav Ilnytskyy, Igor Kovalchuk, Deborah Marie Kurrasch et al. · 2024 · eLife
  31. O-GlcNAcylation and Stem Cells
    Qianyu Liu, Qiang Zhu, Wen Yi · 2024 · Springer eBooks
  32. Proteome dynamics reveal Leiomodin 1 as a key regulator of myogenic differentiation
    Ellen Späth, Svenja Caren Schüler, Ivonne Heinze, Therese Dau, Alberto Minetti, Maleen Hofmann, Katja Hönzke, Julia von Maltzahn, Alessandro Ori‬‬ · 2025 · eLife
  33. Phased ERK function on muscle stem cell plasticity in axolotl
    Chao Yi, Xinxin Liu, Liqun Wang, Song Li, Ji‐Feng Fei · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  34. Investigation of epigenome changes in quiescent fission yeast cells
    Shengyuan Zeng · 2025
  35. Glycolytic flux controls retinal progenitor cell differentiation via regulating Wnt signaling
    Joseph Hanna, Yacine Touahri, Alissa Pak, Lauren Belfiore, Edwin van Oosten, Luke Ajay David, Sisu Han, Yaroslav Ilnytskyy, Igor Kovalchuk, Deborah Marie Kurrasch et al. · 2025 · eLife
  36. Nicotinamide N‐methyltransferase inhibition improves limb function in experimental peripheral artery disease
    Gengfu Dong, Jaewon Choi, Yufen Li, Diana Carolina Müller, Zhuoxin Li, Yangyi E. Luo, TERENCE EDWARD RYAN · 2025 · Physiological Reports
  37. Additional file 1 of Metabolic differences in MSTN and FGF5 dual-gene edited sheep muscle cells during myogenesis
    Chen, Mingming, Li, Yan, Xu, Xueling, Wang, Shuqi, Liu, Zhimei, Qi, Shiyu, Si, Dandan, Zhuo Man, Deng, Shoulong, Liu, Guoshi et al. · 2024 · Figshare
  38. Additional file 3 of RNA sequencing profiles reveal dynamic signaling and glucose metabolic features during bone marrow mesenchymal stem cell senescence
    Sun, Yanan, Yu, Xiao, Xingyu Gao, Zhang, Chang, Sun, Hui, Xu, Kaiyi, Wei, Dongxu, Wang, Qianwen, Zhang, Haiying, Shi, Yingai et al. · 2022 · Figshare
  39. Additional file 1 of In vitro-generated human muscle reserve cells are heterogeneous for Pax7 with distinct molecular states and metabolic profiles
    Axelle Bouche, Benoît Borner, Richard, Chloé, Ysaline Grand, Didier Hannouche, Thomas Laumonier · 2023 · Figshare
  40. Additional file 5 of Metabolic differences in MSTN and FGF5 dual-gene edited sheep muscle cells during myogenesis
    Chen, Mingming, Li, Yan, Xu, Xueling, Wang, Shuqi, Liu, Zhimei, Qi, Shiyu, Si, Dandan, Man, Zhuo, Deng, Shoulong, Liu, Guoshi et al. · 2024 · Figshare
  41. Additional file 1 of Crotonylation of GAPDH regulates human embryonic stem cell endodermal lineage differentiation and metabolic switch
    Jingran Zhang, Guang W. Shi, Junjie Pang, Zhu, Xing, 冯庆彩, Na, Jie, Ma, Wenbin, Liu, Dan, Songyang, Zhou · 2023 · Figshare
  42. Additional file 4 of RNA sequencing profiles reveal dynamic signaling and glucose metabolic features during bone marrow mesenchymal stem cell senescence
    Sun, Yanan, Yu, Xiao, Xingyu Gao, Zhang, Chang, Sun, Hui, Xu, Kaiyi, Wei, Dongxu, Wang, Qianwen, Haiying Zhang, Shi, Yingai et al. · 2022 · Figshare
  43. Additional file 1 of Myoglobin expression by alternative transcript in different mesenchymal stem cells compartments
    Rosella Scrima, Francesca Agriesti, Consiglia Pacelli, Cláudia Piccoli, Pucci, Pietro, Angela Amoresano, Olga Cela, Nappi, Luigi, Tiziana Tataranni, Mori, Giorgio et al. · 2022 · Figshare
  44. Additional file 1 of RNA sequencing profiles reveal dynamic signaling and glucose metabolic features during bone marrow mesenchymal stem cell senescence
    Sun, Yanan, Yu, Xiao, Xingyu Gao, Zhang, Chang, Sun, Hui, Xu, Kaiyi, Wei, Dongxu, Wang, Qianwen, Zhang, Haiying, Shi, Yingai et al. · 2022 · Figshare
  45. Additional file 2 of Metabolic differences in MSTN and FGF5 dual-gene edited sheep muscle cells during myogenesis
    Chen, Mingming, Li, Yan, Xu, Xueling, Wang, Shuqi, Liu, Zhimei, Qi, Shiyu, Si, Dandan, Man, Zhuo, Deng, Shoulong, Liu, Guoshi et al. · 2024 · Figshare
  46. Additional file 4 of Metabolic differences in MSTN and FGF5 dual-gene edited sheep muscle cells during myogenesis
    Chen, Mingming, Li, Yan, Xu, Xueling, Wang, Shuqi, Liu, Zhimei, Qi, Shiyu, Si, Dandan, Man, Zhuo, Deng, Shoulong, Liu, Guoshi et al. · 2024 · Figshare
  47. Additional file 3 of Metabolic differences in MSTN and FGF5 dual-gene edited sheep muscle cells during myogenesis
    Chen, Mingming, Li, Yan, Xu, Xueling, Wang, Shuqi, Liu, Zhimei, Qi, Shiyu, Si, Dandan, Man, Zhuo, Deng, Shoulong, Liu, Guoshi et al. · 2024 · Figshare
  48. Additional file 1 of Excess glucose alone depress young mesenchymal stromal/stem cell osteogenesis and mitochondria activity within hours/days via NAD+/SIRT1 axis
    Betty Linju Yen, Wang, Li-Tzu, Wang, Hsiu-Huang, Hung, Chin-Pao, Hsu, Pei-Ju, Chang, Chia-Chi, Liao, Chien-Yu, Huey‐Kang Sytwu, Yen, Men-Luh · 2024 · Figshare
  49. Additional file 2 of RNA sequencing profiles reveal dynamic signaling and glucose metabolic features during bone marrow mesenchymal stem cell senescence
    Sun, Yanan, Yu, Xiao, Xingyu Gao, Zhang, Chang, Sun, Hui, Xu, Kaiyi, Wei, Dongxu, Wang, Qianwen, Zhang, Haiying, Shi, Yingai et al. · 2022 · Figshare
  50. Distinct epigenetic and metabolic states reflect the regional identity of adult neural stem cells and prime their fate
    Valentina Scandella, Nikolaos M. R. Lykoskoufis, Hadrien Soldati, Livia Di Martino, Tony Teav, Héctor Gallart‐Ayala, Julijana Ivanišević, Simon M. G. Braun, Marlen Knobloch · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  51. Proteome dynamics reveal Leiomodin 1 as a key regulator of myogenic differentiation
    Ellen Späth, Svenja Caren Schüler, Ivonne Heinze, Therese Dau, Alberto Minetti, Maleen Hofmann, Katja Hönzke, Julia von Maltzahn, Alessandro Ori‬‬ · 2026 · eLife
  52. “Quiescence” in the resting zone of the growth plate: a systematic review
    Mahtab Avijgan, Amal Nazaraliyev, Klas Blomgren, D. Gómez-Cabrero, Phillip T. Newton · 2026 · Stem Cells
  53. Loss of Parkin Disrupts Nuclear and Mitochondrial Programs Required for Muscle Regeneration
    Melissa Gourlay, Mah Rukh Abbasi, George Cairns, Madhavee Thumiah-Mootoo, Jeremy Racine, Ha My Ly, Anna Wang, Nikita Larionov, Alexandre Blais, Mireille Khacho et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  54. Altérations épigénétiques des cellules souches musculaires au cours du vieillissement naturel : implications dans la sarcopénie
    Delphine Bauer · 2017 · theses.fr (ABES)
  55. Metabolic characterisation of skeletal muscle stem cells in distinct physiological states
    Francesca Pala · 2017 · theses.fr (ABES)
  56. Caractérisation moléculaire et cellulaire des précurseurs myogéniques du muscle hyperplasique de la truite
    Sabrina Jagot · 2018
  57. Mesenchymal stem cells regulate tissue repair via Angiopoietin-1 signaling and show improved therapeutic potential following mitichondrial preconditioning
    Zeynab Koumaiha · 2019
  58. Rôle du métabolisme sur le devenir des cellules souches musculaires et l'homéostasie du muscle squelettique
    Linda Gsaier · 2018
  59. HosA-mediated epigenetic regulation of growth, virulence, and secondary metabolism in Aspergillus fumigatus
    Zhengyu Zhou, Yuqi Zhu, Renwei Gao, Yamei Wang, Yin Chen, Ling Lu, Yuanwei Zhang · 2026 · Virulence
  60. From skeletal muscle stem cells to tissue atlases : new tools to investigate and circumvent dissociation-induced stress
    Léo Machado · 2019 · theses.fr (ABES)
  61. Investigation of the molecular diversity defining muscle stem cell heterogeneity
    Maria Benavente-Diaz · 2020 · theses.fr (ABES)
  62. Signalisation et implication des phosphoinositides dans la myopathie myotubulaire liée à l'X
    Mélanie Mansat · 2022 · theses.fr (ABES)
  63. Counteracting p38 MAPK activity is a key prerequisite to move towards clinical use of Muscle Stem Cells
    Teoman Ozturk · 2024 · theses.fr (ABES)
  64. dCas9-metabolic enzyme fusions modulate global and locus-specific gene expression
    Kellen Biesbrock, Spencer A. Haws, Harshini Cormaty, Rupa Sridharan, John M. Denu · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  65. Elevated mitochondrial Ca2+ impairs satellite cell pool expansion in response to skeletal muscle injury
    Ahmed S. Shams, Lalitha S. Denduluri, Megan K. Sumera, Ingrid R Aragon, Lauren LaScala, Jae Hwi Sung, Sydney Peng, Sarah J. Cornelius, Sana Ikramuddin, Aiden M. Boechler et al. · 2026 · Stem Cell Reports
  66. Molecular mechanisms, crosstalk and therapeutic potential of novel acylation modifications in cardiovascular and cerebrovascular diseases
    W B Li, Weile Ye, Jiaojiao Wang, Zhiping Liu · 2026 · Acta Pharmaceutica Sinica B
  67. Skeletal muscle biomass as an underappreciated fate of glucose
    Henning Wackerhage, Moritz Eggelbusch, Juha J. Hulmi, Sakari Mäntyselkä · 2026 · American Journal of Physiology-Cell Physiology
  68. Electroacupuncture ameliorates disuse muscular atrophy and inhibits the NLRP3 inflammasome and SIRT1 through miR-133a in a mouse model
    Xing Cai, Yalian Zhang, Zhong Yang, Yuan Jiang, Bin Shu · 2026 · Acupuncture in Medicine
  69. Impaired Myogenic Differentiation Is a Shared Feature Across Genetic Myopathies
    Tyler Soule, Mikhaela B. Slavin, Carly Sabine Pontifex, Mohamed Ziad Dabaja, Arthur Melnyk, Antoine Dufour, Nicolas A. Dumont, Timothy E. Shutt, Gerald Pfeffer · 2026 · International Journal of Molecular Sciences
  70. Porphyromonas gingivalis Drives Trained Immunity via the Glycolysis– SIRT1 Axis to Aggravate Colitis
    Bin Lu, Hanxin Que, Tianhao Chen, Pengcheng Ye, Mengting Wu, Yu Li, Fangchun Shou, Chengxiang Luo, Junjie Bao, Chenyue Jiang et al. · 2026 · Journal Of Clinical Periodontology
  71. Nutrient-sensing pathways in adult stem cells: Orchestrating homeostasis, aging, and disease
    Tianxiong Xiao, Zhiyao Xie, Lijun Yao, Ke Zhao, Yi Arial Zeng, Cheng Hu · 2026 · Seminars in Cell and Developmental Biology
  72. Diet and Lipidomics Mediated Regulation of Mesenchymal Stem Cell Function: Diet, Omics and Stem Cell Connection
    Büşra Başar Gökcen, Büşra Atabılen, Menşure Nur Çelik, Zeynep Büşra Aksoy, Bence László Raposa, Duygu Ağagündüz · 2026 · Biomolecules
  73. Protein Homeostasis and Mitochondrial Quality Control in Neurodegeneration
    Rosa Di Lorenzo, Rola S Zeidan, Riccardo Calvani, Vito Pesce, Emanuele Marzetti, Anna Picca · 2026 · WIREs Mechanisms of Disease
  74. SIRT1 Silences L1 Retrotransposons by Stabilizing Heterochromatin‐Modifying Complexes
    Xiaona Wang, Tianbo Li, Huanyin Tang, Meng Xiao Liu, Qinghua Peng, Xiao Huang, Zhiyong Mao, Ying Jiang, Anke Geng · 2026 · Aging Cell
  75. Lineage relationships in muscle stem cells: linking functional fate to molecular state
    Ohanes Ashekyan, Marie Catenacci, Corentin Guilhot, Tony Lin, Michael A. Rudnicki · 2026 · Frontiers in Cell and Developmental Biology
  76. Physiological Reference Mapping Reveals Context-Dependent Dysregulation of Regenerative Programs in Duchenne Muscular Dystrophy
    Laura Perin, Yan-Yun Liu, Gregory A. Brent, Anna Milanesi · 2026 · Cells
  77. Muscle satellite cell dysfunction in critical illness: niche biology, regenerative failure, and implications for recovery
    Takafumi Ono, Atsushi Asakura · 2026 · Frontiers in Cell and Developmental Biology
  78. Electrochemical metabolic profiling predicts senescence and myogenic fate in undifferentiated myoblasts
    Chang‐Dae Kim, Jin-Kyu Wi, Kyeong‐Mo Koo, Kyeong-Min Cho, Cheol‐Hwi Kim, Taehyung P. Kim · 2026 · Biosensors and Bioelectronics
  79. Intramyocellular lipid droplet–mitochondria uncoupling drives muscle atrophy via metabolite-directed epigenetic reprogramming: a review
    Lingfeng Wu, Ye Wang, Kailian Ma, Yang Liu · 2026 · Frontiers in Endocrinology
  80. Flow Cytometry Analysis of Mitochondrial Function in Muscle Stem Cells
    Lucia Acampora, Melania Murolo, Shahragim Tajbakhsh, Barbara Gayraud-Morel · 2026 · Methods in molecular biology
  81. Measurement of Oxygen Consumption Rate of Primary Mouse Skeletal Muscle Stem Cells and Their Progeny on the Seahorse Analyzer
    Audrey Saugues, Lucie Ancel, Ha My Ly, Lola Lessard, Rémi Mounier, Anita E. M. Kneppers · 2026 · Methods in molecular biology