Modeling of TREX1-dependent autoimmune disease using human stem cells highlights L1 accumulation as a source of neuroinflammation

Thomas, Charles A., Tejwani, Leon, Trujillo, Cleber A., Negraes, Priscilla D., Herai, Roberto H., Mesci, Pinar, Macia, Angela, Crow, Yanick J. +1 more·2017·Cell Stem Cell

Cited by (337)

Items 201–300 of 337

  1. Transposable elements in health and disease: Molecular basis and clinical implications
    Yaqiang Hong, Nian Liu · 2025 · Chinese Medical Journal
  2. Animal Models for the Study of Nucleic Acid Immunity: Novel Tools and New Perspectives
    Isabelle K. Vila, Maxence Frétaud, Dimitriοs Vlachakis, Nadine Laguette, Christelle Langevin · 2020 · Journal of Molecular Biology
  3. Generating and characterizing human telencephalic brain organoids from stem cell-derived single neural rosettes
    H. M. Arif Ullah, Qiju Huang, Simone Chiola, Yueqi Wang, Alex Shcheglovitov · 2025 · Nature Protocols
  4. Advances in transposable elements: from mechanisms to applications in mammalian genomics
    Mei Han, Matthew H. Perkins, Leonardo Santana Novaes, Tao Xu, Hao Chang · 2023 · Frontiers in Genetics
  5. A genome-wide strategy to identify causes and consequences of retrotransposon expression finds activation by BRCA1 in ovarian cancer
    Maisa I. Alkailani, Gareth Palidwor, Ariane Poulin, Raghav Mohan, David Pépin, Barbara C. Vanderhyden, Derrick Gibbings · 2021 · NAR Cancer
  6. Migraine, chronic kidney disease and kidney function: observational and genetic analyses
    Wenqiang Zhang, Li Zhang, Luo Yang, Chenghan Xiao, Xueyao Wu, Peijing Yan, Huijie Cui, Chao Yang, Jingwei Zhu, Xuan Wu et al. · 2023 · Human Genetics
  7. Autism spectrum disorders: Challenges and perspectives
    Alysson Renato Muotri · 2018 · Developmental Neurobiology
  8. Cell-type-specific transposon demethylation and TAD remodeling in aging mouse brain
    Qiurui Zeng, Wenliang Wang, Wei Tian, Amit Klein, Anna Bartlett, Hanqing Liu, Joseph R. Nery, Rosa Castanon, Julia K. Osteen, Nicholas D. Johnson et al. · 2026 · Cell
  9. Non-coding RNAs in stroke pathology, diagnostics, and therapeutics
    Nikita Potemkin, Andrew N. Clarkson · 2022 · Neurochemistry International
  10. Transcriptional Landscape of Repetitive Elements in Psoriatic Skin from Large Cohort Studies: Relevance to Psoriasis Pathophysiology
    Vidya S. Krishnan, Sulev Kõks · 2023 · International Journal of Molecular Sciences
  11. The TREX1 Dinosaur Bites the Brain through the LINE
    Jose Luis Garcia-Perez, Marta Eugenia Alarcón-Riquelme · 2017 · Cell stem cell
  12. Genome Replication Is Associated With Release of Immunogenic DNA Waste
    Nadja Schubert, Tina Schumann, Elena Daum, Karolin Flade, Yan Ge, Lara Hagedorn, Winfried Edelmann, Luise Müller, Marc Schmitz, Gunnar Kuut et al. · 2022 · Frontiers in Immunology
  13. Toward Elucidating Epigenetic and Metabolic Regulation of Stem Cell Lineage Plasticity in Skin Aging
    Ying Lyu, Yejing Ge · 2022 · Frontiers in Cell and Developmental Biology
  14. The Sixth Sense: Self-nucleic acid sensing in the brain
    Tyler J. Dorrity, Heegwon Shin, Jake A. Gertie, Hachung Chung · 2024 · Advances in immunology
  15. Manipulating cell fate while confronting reproducibility concerns
    Jeannette M. Osterloh, Kevin Mullane · 2018 · Biochemical Pharmacology
  16. Cerebral Microangiopathy in Leukoencephalopathy With Cerebral Calcifications and Cysts: A Pathological Description
    Guy Helman, Angela Nicole Viaene, Asako Takanohashi, Marjolein Breur, Rebecca S. Berger, Sarah Woidill, John R. Cottrell, Raphael Schiffmann, Yanick Joseph Crow, Cas Simons et al. · 2020 · Journal of Child Neurology
  17. TREX1 Deficiency Induces ER Stress-Mediated Neuronal Cell Death by Disrupting Ca2+ Homeostasis
    Debasish Halder, Su-Jin Jeon, Ji‐Yong Yoon, Jeong-Ju Lee, Soo Young Jun, Min-Hyuk Choi, Bohyeon Jeong, Duk Hyun Sung, Da Yong Lee, Byoung Joon Kim et al. · 2022 · Molecular Neurobiology
  18. Sort Your Self Out!
    Carolina Uggenti, Yanick Joseph Crow · 2018 · Cell
  19. Differential Responses of LINE-1 in the Dentate Gyrus, Striatum and Prefrontal Cortex to Chronic Neurotoxic Methamphetamine: A Study in Rat Brain
    Anna Moszczyńska · 2020 · Genes
  20. Modeling Inflammation on Neurodevelopmental Disorders Using Pluripotent Stem Cells
    Beatriz Freitas, Patrícia Cristina Baleeiro Beltrão-Braga, Maria Carolina Marchetto · 2020 · Advances in neurobiology
  21. High clinical heterogeneity in a Chinese pedigree of retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S)
    Nina Xie, Qiying Sun, Jinxia Yang, Yangjie Zhou, Hongwei Xu, Yafang Zhou, Yafang Zhou · 2021 · Orphanet Journal of Rare Diseases
  22. Long INterspersed nuclear Elements (LINEs) in brain and non-brain tissues of the rat
    Gianfranco Giorgi, Marco Virgili, Barbara Monti, Brunella Del Re · 2018 · Cell and Tissue Research
  23. Advances and applications of brain organoids in central nervous system disorders: Bridging the gap from laboratory to clinic
    Changle Fang, Qiulin Wang, Qiu‐Xia Xiao, Xiao-Xing Cai, Ruo‐Lan Du, Lu‐Lu Xue, Xiaohe Tian, Liu‐Lin Xiong · 2025 · Neural Regeneration Research
  24. HIV suppressors against LINE-1: one functions as two
    Juan Du, Ke Zhao · 2021 · Critical Reviews in Biochemistry and Molecular Biology
  25. LINE-1 retrotransposon activation drives age-associated inflammation via cytoplasmic cDNA-STING/type I interferon signalling: therapeutic potential of reverse transcriptase inhibition
    Arshad Mehmood, Yuezhen Xue, Habab Merghani Yassin, Mohammad Aref Zubair, Syed Adnan Rahmat, Aftab Ahmad · 2025 · Współczesna Onkologia
  26. An Exploration of Organoid Technology: Present Advancements, Applications, and Obstacles
    Isha Mishra, Komal Gupta, Raghav Mishra, Kajal Chaudhary, Vikram Sharma · 2023 · Current Pharmaceutical Biotechnology
  27. Suppressors of cGAS‐STING are downregulated during fin‐limb regeneration and aging in aquatic vertebrates
    Sabateeshan Mathavarajah, Andrew W. Thompson, Matthew R. Stoyek, Thomas Alexander Quinn, Stéphane Roy, Ingo Braasch, Graham Dellaire · 2023 · Journal of Experimental Zoology Part B Molecular and Developmental Evolution
  28. Asteroid impact: the potential of astrocytes to modulate human neural networks within organoids
    Sailee S. Lavekar, Megh Dipak Patel, Maria Dolores Montalvo Parra, Robert Krencik · 2023 · Frontiers in Neuroscience
  29. T‐Rex escaped from the cytosolic park: Re‐thinking the impact of TREX1 exonuclease deficiencies on genomic stability
    Hervé Técher · 2024 · BioEssays
  30. Long-Term Potentiation and Closed-Loop Learning in Paired Brain Organoids for CNS Drug Discovery
    Corey M. Rountree, Eva Schmidt, Nicholas Coungeris, Victoria Alstat, Andrew S. LaCroix, Megan Morris, Michael John Moore, J. Lowry Curley · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  31. Dormant viral pathways underlie space-induced neural senescence
    Aline Maria Araújo Martins, Hideyuki Nakashima, Ángela Macia, Taichi Umeyama, Satoshi Miyashita, Livia LS Nascimento, Luisa Bulcao Vieira Coelho, Pinar Mesci, Erik Viirre, Nicole Suarez et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  32. Pharmacological evaluation of drug therapies in Aicardi-Goutières syndrome: insights from patient-derived neural stem cells
    Stefania Braidotti, Rosalba Monica Ferraro, Raffaella Franca, Elena Cat Genova, Francesco Giambuzzi, Andrea Mancini, Valentina Marinozzi, Letizia Pugnetti, Giulia Zudeh, Alessandra Tesser et al. · 2025 · Frontiers in Pharmacology
  33. Insights into Noncanonical and Diversified Functions of ABCF1: From Health to Disease
    Junyi Duan, Prince Saini, Yick W. Fong · 2025 · Journal of Molecular Biology
  34. Role of LINE-1 in the nervous system and neurological disorders
    Huiling Hu, Xiaoxia Lu, Rihui Zhong, Xiuli Liu, Jie Wei, Chaohui Duan, Nannan Sun · 2025 · Chinese Medical Journal
  35. LINE-1 retrotransposition in a mouse TDP-43 model of neurodegeneration marks motor cortex neurons for cell-intrinsic and cell non-autonomous programmed cell death
    Shreevidya Korada, Oliver H. Tam, Hunter C. Greco, Molly Hammell, Josh Dubnau, Roger B. Sher · 2025 · PLoS Genetics
  36. Generalized nuclear localization of retroelement transcripts
    Simanti Das, Amanda E. Jones, John Abrams · 2022 · Mobile DNA
  37. Proceedings of the inaugural Dark Genome Symposium: November 2022
    Jef D. Boeke, Kathleen H. Burns, Katherine Bakshian Chiappinelli, Marie Classon, John M. Coffin, Daniel DeCarvalho, Joseph D. Dukes, Benjamin D. Greenbaum, George Kassiotis, Sarah K. Knutson et al. · 2023 · Mobile DNA
  38. Condensin-mediated restriction of retrotransposable elements facilitates brain development in Drosophila melanogaster
    Bert I. Crawford, Mary Jo Talley, Joshua Russman, James Riddle, Sabrina Torres, Troy Williams, Michelle S. Longworth · 2024 · Nature Communications
  39. Transposable Elements Cross Kingdom Boundaries and Contribute to Inflammation and Ageing
    Timothy J. Chalmers, Lindsay E. Wu · 2020 · BioEssays
  40. Steady-state neuron-predominant LINE-1 encoded ORF1p protein and LINE-1 RNA increase with aging in the mouse and human brain
    Bonnifet, Tom, Sinnassamy, Sandra, Massiani-Beaudoin, Olivia, Mailly, Philippe, Monnet, Heloise, Loew, Damarys, Lombard, Berangere, Servant, Nicolas, Joshi, Rajiv L, Fuchs, Julia · 2025 · eLife
  41. A scoping review of stem cell models of leukodystrophies: advances in understanding pathophysiological mechanisms
    Alexandra Chapleau, Stefanie Perrier, Thomas M. Durcan, Geneviève Bernard · 2025 · npj Genomic Medicine
  42. A zebrafish reporter line reveals immune and neuronal expression of endogenous retrovirus
    Holly A. Rutherford, Amy Clarke, Emily V. Chambers, Jessica J. Petts, Euan G. Carson, Hannah M. Isles, Alejandra Duque‐Jaramillo, Stephen A. Renshaw, Jean‐Pierre Levraud, Noémie Hamilton · 2022 · Disease Models & Mechanisms
  43. Snapshots of genetic copy-and-paste machinery in action
    Gaël Cristofari · 2024 · Nature
  44. Beyond Trypanosoma cruzi: LINE-1 Activation as a Driver of Chronic Inflammation in Chagas Disease
    Marina O.S. Dias, Aline Silva Moraes, Tatiana Shiroma, Vitória França dos Santos Pessoa, Antonio Ermoges, Tamires Emanuele Vital, Luciana Hagström, Davi Emanuel Ribeiro de Sousa, Márcio Botelho de Castro, Bruno Stéfano Lima Dallago et al. · 2025 · International Journal of Molecular Sciences
  45. RNA Editing in Interferonopathies
    Loredana Frassinelli, Silvia Galardi, Silvia Anna Ciafrè, Alessandro Michienzi · 2020 · Methods in molecular biology
  46. Mendelian disorders of immunity related to an upregulation of type I interferon
    Marie‐Louise Frémond, Yanick Joseph Crow · 2020 · Elsevier eBooks
  47. Genetics, TREX1 Mutations
    Seyed Alireza Hosseini, Anatália Labilloy · 2019 · StatPearls
  48. Activation of endogenous retroviruses during brain development causes neuroinflammation
    Marie E. Jönsson, R. Garza, Yogita Sharma, Rebecca Petri, E. Södersten, Jenny G. Johansson, P. Johansson, Diahann A. M. Atacho, Karolina Pircs, Sofia Madsen et al. · 2020 · bioRxiv
  49. Nuclear Translocation of S100A9 Triggers Senescence of Human Amnion Fibroblasts by De‐Repressing LINE1 Via Heterochromatin Erosion at Parturition
    Fan Zhang, Meng‐Die Li, Fan Pan, Wen‐Jia Lei, Yang Xi, Li‐Jun Ling, Leslie Myatt, Kang Sun, Wangsheng Wang · 2025 · Advanced Science
  50. SLFN11 Restricts LINE-1 Mobility
    Zhongjie Ye, Yuqing Duan, Ao Zhang, Zixiong Zhang, Saisai Guo, Qian Liu, Dongrong Yi, Xinlu Wang, Jianyuan Zhao, Quanjie Li et al. · 2025 · Cells
  51. The interferon-stimulated gene product HERC5 inhibits human LINE-1 retrotransposition with an ISGylation-independent mechanism
    Kei Nishimori, Ahmad Luqman-Fatah, Yuzo Watanabe, Mari Takahashi, Takuhiro Ito, Fuyuki Ishikawa, Tomoichiro Miyoshi · 2026 · Nucleic Acids Research
  52. The role of transposable elements activity in genomic instability and their relationship to aging process
    Jingran Hu, Tianhao Mao, Kainan Huang, Shangzhi Yang, Wenrui Yu, Jiacheng Huang, Shiqi Jin, Chuanyu Sun, Zeyidan Jiapaer, Xiaohai Wang · 2026 · Cell Cycle
  53. Effects of Sevoflurane on the Development of a Human Brain Microphysiological System
    Qun Li, Lixuan Ding, Itzy E. Morales Pantoja, Navid Modiri, Lena Smirnova, Cyrus David Mintz · 2026 · International Journal of Molecular Sciences
  54. LINE-1 retrotransposons: Multifaceted functions and regulatory mechanisms in health and disease
    Xingyue Liu, Caizhou Zhong, Shenglan Wang, 黄清育, Zheng Li · 2026 · Molecular Therapy — Nucleic Acids
  55. Type I Interferonopathies: Fifteen Years On, From Concept to Therapeutic Perspectives
    Dilara Ünal, Isabelle Melki, Marie‐Louise Frémond · 2026 · Current Rheumatology Reports
  56. Dendritic Cell Differentiation from Human Induced Pluripotent Stem Cells: Challenges and Progress
    Nélio Alessandro de Jesus Oliveira, Handan Sevim · 2022 · Stem Cells and Development
  57. Age-Related Variation in DNA Methylation
    Kelsey Keith, Jean‐Pierre J. Issa, Shoghag B. Panjarian · 2022 · Springer eBooks
  58. Derivation of cortical interneurons from human pluripotent stem cells to model neurodevelopmental disorders
    Kesavan Meganathan, Ramachandran Prakasam, Komal Kaushik, Irene Antony, Gareth Chapman, Kristen L. Kroll · 2022 · Elsevier eBooks
  59. Prospects for the study of transposons in the pathogenesis of autoimmune diseases
    Rustam Nailevich Mustafin · 2022 · Kazan medical journal
  60. Brainstem organoids from human pluripotent stem cells contain neural crest population
    Nobuyuki Eura, Takeshi K. Matsui, Joachim Luginbühl, Masaya Matsubayashi, Hitoki Nanaura, Tomo Shiota, Kaoru Kinugawa, Naohiko Iguchi, Takao Kiriyama, Canbin Zheng et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  61. LINE-1 replication in a mouse TDP-43 model of neurodegeneration marks motor cortex neurons for cell-intrinsic and non-cell autonomous programmed cell death
    Shreevidya Korada, Oliver H. Tam, Hunter C. Greco, Molly Hammell, Josh Dubnau, Roger B. Sher · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  62. Cerebral organoids: a promising model in cellular technologies
    Т. А. Шнайдер · 2018 · Vavilov Journal of Genetics and Breeding
  63. Nef Suppresses LINE-1 Retrotransposition through Two Distinct Mechanisms
    Yu Wang, Ke Zhao, Yifei Zhao, Zihan Zhao, Shaohua Wang, Juan Du · 2022 · Journal of Virology
  64. Transcription-Replication Conflicts and Incomplete Replication as a Cause of Micronuclei-Driven Chromoanagenesis
    Hervé Técher, Philippe Pasero · 2025 · Methods in molecular biology
  65. Gigaxonin Potentiates Antiviral Innate Immune Responses by Targeting cGAS and TREX1
    Ben‐Zhe Ji, Jie Wang, Yi Tu, Shan Zhang, Yong‐Sheng Wei, Yan He, Bin Zhang, Qing‐Qing Zhao, Hao‐Min Hu, Yu Liu · 2025 · Advanced Science
  66. LINE‐1 Retroelement Activation and Neuroinflammation in Persons With Fanconi Anemia
    Allison L. Bartlett, Kristie N. Ramos, Jamen R. Bartlett, Kenneth S. Ramos, Nathan Luebbering, Kasiani C. Myers, Parinda A. Mehta, Stella M. Davies · 2025 · Pediatric Blood & Cancer
  67. The intersection of TREX1, cGAS, STING and the DNA damage theory of aging
    Kate M. Jones, Samuel D. Chauvin, Jonathan J. Miner · 2025 · Frontiers in Aging
  68. Plasma EV LINE-1 mRNA as a diagnostic biomarker for differentiating Alzheimer’s disease from non-Alzheimer’s dementias
    Ming Li, Qian Yu, Shuyi Yu, Qian Cheng, Siyu Wu, Yan Jin, Zhikang Cui, Hang Chen, Xinyu Zhao, Xiaoben Wu et al. · 2026 · Alzheimer s Research & Therapy
  69. Retrotransposons in embryogenesis and neurodevelopment
    Mary Jo Talley, Michelle S. Longworth · 2024 · Biochemical Society Transactions
  70. Identification of LINE retrotransposons and long non-coding RNAs expressed in the octopus brain
    Giuseppe Petrosino, Giovanna Ponte, Massimiliano Volpe, Ilaria Zarrella, Concetta Langella, Giulia Di Cristina, Sara Finaurini, Monia Teresa Russo, Swaraj Basu, Francesco Musacchia et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  71. Transposable Elements in Human Diseases: Evolutionary and Therapeutic Perspectives
    Kavi Shah, Ahmet Can Berkyurek · 2022 · Preprints.org
  72. Steady-state neuron-predominant LINE-1 encoded ORF1p protein and LINE-1 RNA increase with aging in the mouse and human brain
    Tom Bonnifet, Sandra Sinnassamy, Olivia Massiani-Beaudoin, Philippe Mailly, Héloïse Monnet, Damarys Loew, Bérangère Lombard, Nicolas Servant, Rajiv L. Joshi, Julia Fuchs · 2024 · eLife
  73. Inhibition of cytosolic DNA sensing and transposon activity safeguards pluripotency
    Ferran Garcia-Llagostera, Audrey L. K. Putman, Alexandros Choromidis, Bryony J. Leeke, Klaudia Stanik, Antonia Ramos, Benjamin Moyon, Jesús Gil, Alexis R. Barr, Michelle Percharde · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  74. Cell-Type-Specific Transposable Element Demethylation and TAD Remodeling in the Aging Mouse Brain
    Qiurui Zeng, Wei Tian, Amit Klein, Anna Bartlett, Hanqing Liu, Joseph R. Nery, Rosa Castanon, Julia K. Osteen, Nicholas D. Johnson, Wenliang Wang et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  75. Inhibition of retrotransposition improves health and extends lifespan of SIRT6 knockout mice
    Matthew Simon, Michael Van Meter, Julia Ablaeva, Zhonghe Ke, Raul S. González, Taketo Taguchi, Marco De Cecco, Katerina I. Leonova, Valeria Kogan, Stephen L. Helfand et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  76. Endogenous DAMPs, Category II: Constitutively Expressed, Injury-Modified Molecules (Cat. II DAMPs)
    Walter Gottlieb Land · 2018 · Springer eBooks
  77. Disease Modeling of Hematological and Immunological Disorders Using Induced Pluripotent Stem Cells
    Megumu K. Saito · 2019 · Current human cell research and applications
  78. Improved ThwaRTing of Genome Symbionts
    John L. Goodier · 2019 · Cell chemical biology
  79. Fundamentals of extrachromosomal circular DNA in human cells - Genetic activities as regards cancer promotion alongside chromosomal DNA
    Reinhard H. Dennin · 2020 · World Journal of Advanced Research and Reviews
  80. Exosome derived from mesenchymal stem cells enhance autophagy and inhibit iNOS/TXNIP/NLRP3 inflammasome axis in injured spinal cord
    Bin Lv, Lei Wang, Anquan Huang, Tianming Zou, Jishan Yuan · 2020
  81. Implications of Endogenous Retroelements in the Etiopathogenesis of Systemic Lupus Erythematosus
    Kennedy C. Ukadike, Tomas Mustelin · 2021 · Journal of Clinical Medicine
  82. Pluripotent stem cell–derived brain-region-specific organoids
    Phuong Trang Nguyen, Hongjun Song, Guo‐li Ming · 2021 · Elsevier eBooks
  83. Recent Advances in Brains Organoids: Opportunities and Challenges
    Jing Yit Pua, Izzah Madihah Rosli, Mei Xuan Ooi, Mohd Nor Azim Ab Patar · 2022 · Stem cell biology and regenerative medicine
  84. Interferon regulatory factor 3 upregulates the Treg recruitment factor CCL22 in response to double-stranded DNA in cancer cells
    Jihyun Kim, Jocelyn Pena, Hannah P. McQueen, Lingwei Kong, Dina Michael, Pamela R. Cook · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  85. Faculty Opinions recommendation of L1 drives IFN in senescent cells and promotes age-associated inflammation.
    Michael Zhang, Zhenyu Xuan · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  86. Faculty Opinions recommendation of Cell fitness screens reveal a conflict between LINE-1 retrotransposition and DNA replication.
    Daniel Diniz De Carvalho, Charles A. Ishak · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  87. Faculty Opinions recommendation of L1 drives IFN in senescent cells and promotes age-associated inflammation.
    Jean Pieters, Ravindra Mode · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  88. Nuclear translocation of LINE-1 encoded ORF1p alters nuclear envelope integrity and disrupts nucleocytoplasmic transport in human neurons
    Rania Znaidi, Olivia Massiani-Beaudoin, Philippe Mailly, Héloïse Monnet, The Brainbank Neuro-CEB Neuropathology Network, Rajiv L. Joshi, Julia Fuchs · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  89. L1Hs and MPP8 Genes Expression Correlation with Several Types of Carcinoma Tumors
    Wisam Abdan Wawi AL Abdullah · 2023 · International Journal of Medical Science and Clinical Research Studies
  90. Condensin-mediated restriction of retrotransposable elements facilitates brain development in Drosophila melanogaster
    Bert I. Crawford, Mary Jo Talley, Joshua Russman, James Riddle, Sabrina Torres, Troy Williams, Michelle S. Longworth · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  91. Additional file 6 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Fumihiko Urano, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner et al. · 2021 · Figshare
  92. Additional file 13 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Fumihiko Urano, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner et al. · 2021 · Figshare
  93. Additional file 5 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Fumihiko Urano, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner et al. · 2021 · Figshare
  94. Additional file 10 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Fumihiko Urano, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner et al. · 2021 · Figshare
  95. Additional file 1 of Brain organoid: a 3D technology for investigating cellular composition and interactions in human neurological development and disease models in vitro
    Oluwafemi Solomon Agboola, Xinglin Hu, Zhiyan Shan, Yanshuang Wu, Lei Lei · 2021 · Figshare
  96. Additional file 4 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Fumihiko Urano, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner et al. · 2021 · Figshare
  97. Additional file 8 of Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7
    Kesavan Meganathan, Ramachandran Prakasam, Dustin Baldridge, Paul M. Gontarz, Bo Zhang, Fumihiko Urano, Azad Bonni, Susan E. Maloney, Tychele N. Turner, James E. Huettner et al. · 2021 · Figshare
  98. Targeting the paralog protein for degradation accounts for the opposite roles of NRBP1 and NRBP2 in regulating LINE1 retrotransposition
    Wei Yang, Shaobo Cong, Jennifer Schwarz, Thilo Schulze, Sara Ullrich, Kristina Falkenstein, Denis Ott, Pia Eixmann, Angelica Trentino, Antje Thien et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  99. The advancements of organoids push the boundaries of glioblastoma research
    Gang Cui, Song Xue, Xiaoshan Wang, Wei Song · 2024 · Postgraduate Medical Journal
  100. De-repression of Transposable Elements by Histone Hyperacetylation Leads to Sterile Inflammation in Preeclampsia
    Madapura M. Pradeepa, Manthan Patel, Ahmed Ali, Adrianna Dąbrowska, Fanny Boulet, Rashmi Kulkarni, Charlie Ince, Ajay Sinha · 2025 · Research Square