Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids

Artegiani, Benedetta, van Voorthuijsen, Lisa, Lindeboom, Rik G.H., Seinstra, Daniëlle, Heo, Inha, Tapia, Pablo, López-Iglesias, Carmen, Postrach, Daniel +10 more·2019·Cell Stem Cell
DOI 10.1016/j.stem.2019.04.017

Cited by (218)

Items 201–218 of 218

  1. Nanopuncturing‐Enabled Efficient Gene Editing for Isogenic Human iPSC‐Derived Organoid Engineering
    Muhammad Waseem Ghani, Yutong Kong, Ambreen Iqbal, Weidong Shao, Deyuan Yang, Gaole Dai, Yuan Wang, Lei Qiu, Xiaoliang Yang, Chunyan Li et al. · 2025 · Advanced Functional Materials
  2. Additional file 1 of Human liver single nucleus and single cell RNA sequencing identify a hepatocellular carcinoma-associated cell-type affecting survival
    Marcus Alvarez, Jihane N. Benhammou, Nicholas Darci-Maher, Samuel W. French, Steven B. Han, Janet S. Sinsheimer, Vatche Garen Agopian, Pisegna, Joseph R., Päivi Pajukanta · 2022 · Figshare
  3. Preclinical mouse models for studying cholangiocarcinoma
    Shanru Yang, Chaodi Bao, Yuan Li, Yangxiang Ou, Yifan Jiang, Wenjie Xu, Dongfang Zheng, Na Li, Mengjie Yang, Fuyan Wang et al. · 2026 · Liver Research
  4. Functional characterization of BAP1 mutations in genome edited cholangiocarcinoma organoids: Role in cell death and drug responses
    Wunan Mi, Shaojun Shi, Imre Firmin Schene, Indi P. Joore, Henk P. Roest, Sabine A. Fuchs, Luc J. W. van der Laan, Monique M. A. Verstegen · 2026 · iScience
  5. CELLULAR BIOTECHNOLOGIES IN THE MODELING OF CARCINOGENESIS AND THEIR POTENTIAL IN PRECISION MEDICINE
    Наханов Азиз Куралбаевич, Sabit Kabdyshevich Kokanov, A. A. Terebay, L. G. Marakhovskaya · 2026 · Biosafety and Biotechnology
  6. Hepatocyte-targeted Bap1 reduction in the liver primes an inflammatory transcriptional response
    William Nenad, Peyton C. Kuhlers, Ian R. Sturgill, Irene Biju, Max Bucklan, Lindsey Hernandez, Lee‐Ching Zhu, Katherine A. Hoadley, Jesse R. Raab · 2026 · G3 Genes Genomes Genetics
  7. How to efficiently establish animal models of cholangiocarcinoma: challenges and inspiration
    Ruiqiang Gou, Ping Yue, Peng Liu, Jinyu Zhao, Chunfei Huang, Kiyohito Tanaka, Peng Foo Wong, Rungsun Rerknimitr, Jong Ho Moon, Tan T Cheung et al. · 2026 · Medical Review
  8. Organoid Perturbations as Tools to Explore Cellular Function and Plasticity
    Katharina Eva Kohl, Georg A. Busslinger · 2026 · Annual Review of Genomics and Human Genetics
  9. Identification and characterization of key epigenetic drivers of breast cancer
    Mariana Gomes da Silva Araujo · 2024 · theses.fr (ABES)
  10. Fusion oncogenes in cancer: organoid models and novel therapeutic approaches
    Lucia Bracesco, Delilah F. G. Hendriks, Benedetta Artegiani · 2026 · BMC Biology
  11. Distinct functions of PBRM1 and BAP1 reconcile the course of kidney cancer evolution and disease progression
    Daqi Deng, Hugang Feng, Annika Fendler, Yuliia Dovga, Fiona Byrne, Charlotte Spencer, Alice C. Martin, Ángel Fernández-Sanromán, Omar Bouricha, Scott T.C. Shepherd et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  12. Integrating experimental biology, computational methods, and artificial intelligence in anticancer drug discovery: Bridging the translational gap
    Cromwel Tepap Zemnou, Ramelle Ngakam, Schelsea Siham Delore Tepap, Fredy Brice Nemg Simo, Fernando Berton Zanchi, Armel Jackson Seukep, Arnaud Fondjo Kouam, Nguyen Tien Huy · 2026 · Computers in Biology and Medicine
  13. Inducing physiological polarity and performing gene editing using CRISPR–Cas9 in human trophoblast organoids
    Liheng Yang, Joshua Hatterschide, Rizban E Worota, Kaila A Cooley, Carolyn B. Coyne · 2026 · Nature Protocols
  14. From liver organoids to regulatory platforms for precision hepatology: Advances and challenges
    Xi Xu, Caimeng Zhuang, Yuchen Liu, Yang Zhang, Yannan Fang, Frank J. Gonzalez, Tingting Yan, Haiping Hao · 2026 · The Innovation Drug Discovery
  15. The epigenetic KMT5C-HDAC1 axis promotes hepatocellular carcinoma stemness and progression through SERPINA4 repression and chromatin compaction
    Hongbin Huang, Caini Huang, Pangfei Yang, Shiping Xian, Yang Liu, Ruiyang Liu, Zhiju Zhao, Fei Xiao · 2026 · Oncogene
  16. Doxycycline Modulates Uveal-Melanoma-Associated Marker Expression in BAP1-Repressed Human Ocular Organoids
    Ethan Anthony Chiu, Timothy A. Blenkinsop · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  17. Liver organoids: modelling complexity in homeostasis and disease
    Anna M. Dowbaj, Meritxell Huch · 2026 · FEBS Letters
  18. Powering the liver toxicity assessment in the organoid era
    Xinlan Yu, Li Shen, Xianchao Zhou, Jian He · 2026 · Clinical Science