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Cited by 114Neuroendocrine Tumor Research AdvancesPancreatic function and diabetesPancreatic and Hepatic Oncology Research

Insulinoma

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Mathur, Aarti, Gorden, Philip, Libutti, Steven K.·2009·Surgical Clinics of North America
DOI 10.1016/j.suc.2009.06.009PMC PMC3470467
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Abstract

Insulinoma is a rare neuroendocrine tumor with an incidence of 4 per 1 million persons per year, which may occur as a unifocal sporadic event in patients without an inherited syndrome or as a part of multiple endocrine neoplasia type 1. Key neuroglycopenic and hypoglycemic symptoms in conjunction with biochemical proof establish the diagnosis. Once the diagnosis is established, the insulinoma is preoperatively localized within the pancreas with the goal of surgical excision for cure. This review discusses the historical background, diagnosis, and management of sporadic insulinoma.

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References 70 · Cited by 114

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Authors
Mathur, A., Gorden, P., & Libutti, S. K.
Affiliations
  • National Institutes of Health (US)
  • Albert Einstein College of Medicine (US)
Corresponding author
Libutti, Steven K.
ORCID
Venue
Surgical Clinics of North America
Publisher
Elsevier BV
Published
2009-10
Volume
89
Issue
5
Pages
1105-1121
ISSN
0039-6109 (ISSN-L)
DOI
10.1016/j.suc.2009.06.009
PMC
PMC3470467
OpenAlex
W4236418830
Cited by
114
References
70
Citations by year
2026: 3 · 2025: 10 · 2024: 4 · 2023: 17 · 2022: 8 · 2021: 5 · 2020: 10 · 2019: 3 · 2018: 5 · 2017: 7 · 2016: 4 · 2015: 9 · 2014: 8 · 2013: 7 · 2012: 4
FWCI
0.57
Type
journal article
Language
en
Open access
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Surgical Clinics of North America (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institutes of Health (Z99 DK999999, Z99 OD999999, Z99 DA999999)
Topics
  • Health Sciences › Medicine › Epidemiology › Neuroendocrine Tumor Research Advances
  • Health Sciences › Medicine › Surgery › Pancreatic function and diabetes
  • Health Sciences › Medicine › Oncology › Pancreatic and Hepatic Oncology Research
Keywords
insulinoma, neuroendocrine tumors, multiple endocrine neoplasia type 1, hypoglycemia, neuroglycopenic symptoms, surgical excision, diagnosis
MeSH terms
Combined Modality Therapy, Diagnosis, Differential, Diagnostic Imaging, Humans, Insulinoma, Neoplasm Metastasis, Pancreatic Neoplasms, Liver Transplantation

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