Multivariate optimization of a liquid–liquid extraction of the EPA-PAHs from natural contaminated waters prior to determination by liquid chromatography with fluorescence detection

Brum, Daniel Mares; Cassella, Ricardo J.; Pereira Netto, Annibal D.

doi:10.1016/j.talanta.2007.09.013

Multivariate optimization of a liquid–liquid extraction of the EPA-PAHs from natural contaminated waters prior to determination by liquid chromatography with fluorescence detection

This paper reports the multivariate optimization of a liquid-liquid extraction procedure for the determination of 15 EPA-polycyclic aromatic hydrocarbons (PAHs) by high-performance liquid chromatography with fluorescence detection. A Doehlert design was used to find optimum conditions for the pro…