The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Extracellular Vesicles: Unique Intercellular Delivery Vehicles
Open accessAbstract
Extracellular vesicles (EVs) are a heterogeneous collection of membrane-bound carriers with complex cargos, including proteins, lipids and nucleic acids. While release of EVs was previously thought to be only a mechanism to discard nonfunctional cellular components, increasing evidence implicates EVs as key players in intercellular and even interorganismal communication. EVs confer stability and can direct their cargoes to specific cell types. EV cargoes also appear to act in a combinatorial manner to communicate directives to other cells. This review will focus on recent findings and knowledge gaps in the area of EV biogenesis, release, and uptake. In addition, we highlight examples whereby EV cargoes control basic cellular functions, including motility and polarization, immune responses, and development, as well as contribute to diseases, such as cancer and neurodegeneration.
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Cites
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Cited by
Current knowledge on exosome biogenesis and release
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Metadata
- Authors
- Maas, S. L. N., Breakefield, X. O., & Weaver, A. M.
- Venue
- Trends in Cell Biology
- Publisher
- Elsevier BV
- Published
- 2017-03
- Volume
- 27
- Issue
- 3
- Pages
- 172-188
- ISSN
- 0962-8924 (ISSN-L)
- OpenAlex
- W2565271826
- Cited by
- 1,429
- References
- 22
- FWCI
- 6.90
- Type
- journal article
- Language
- en
- Open access
- green
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