Cited by 175Cardiac electrophysiology and arrhythmiasIon channel regulation and functionCardiac Arrhythmias and Treatments

The DOI matches its Crossref record; 59 of the 59 references it cites were found in a registry or an index.

Studying Cardiac Arrhythmias in the Mouse—A Reasonable Model for Probing Mechanisms?

Nerbonne, J·2004·Trends in Cardiovascular Medicine

DOI 10.1016/j.tcm.2003.12.006

Open this paper in CoChat — free account

Abstract

The normal mechanical functioning of the heart depends on proper electrical functioning, reflected in the sequential activation of pacemaker cells, and the normal propagation of activity through the ventricles. Myocardial electrical activity is evident in the form of action potentials, reflecting the activation (and inactivation) of depolarizing (Na(+), Ca(2+)) and repolarizing (K(+)) current channels. There are multiple types of myocardial K(+) channels, contributing to regional differences in action potential waveforms and to the generation of normal cardiac rhythms. The conduction and propagation of activity through the myocardium depends on electrical coupling between cells, mediated by gap junction channels. In the diseased myocardium, action potential waveforms and conduction are affected markedly, owing to changes in the functional expression of repolarizing K(+) and other channels. These changes can lead to desynchronization of the heart and to arrhythmia generation. There is presently greater interest in defining the cellular, molecular, and systemic mechanisms contributing to the generation and the maintenance of cardiac arrhythmias. Although a variety of experimental (animal) model systems have been (and are being) exploited in these efforts, the mouse is being used increasingly, due to the ease with which molecular genetic strategies can be applied. The important issue is whether the mouse is an appropriate model system to explore arrhythmia mechanisms.

Integrity signals

Registry

Crossref · 10.1016/j.tcm.2003.12.006

Cites

59 of 59 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Handbook of Physiology.
Plum, F. (1960) · Archives of Neurology · doi:10.1001/archneur.1960.03840090124020 · Cited by 10,388
A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel
Sanguinetti, M. C., Jiang, C., Curran, M. E., & Keating, M. T. (1995) · Cell · doi:10.1016/0092-8674(95)90340-2 · Cited by 2,422
Coassembly of KVLQT1 and minK (IsK) proteins to form cardiac IKS potassium channel
Sanguinetti, M. C., Curran, M. E., Zou, A., Shen, J., Specter, P. S., Atkinson, D. L., & Keating, M. T. (1996) · Nature · doi:10.1038/384080a0 · Cited by 1,765
KvLQT1 and IsK (minK) proteins associate to form the IKS cardiac potassium current
Barhanin, J., Lesage, F., Guillemare, E., Fink, M., Lazdunski, M., & Romey, G. (1996) · Nature · doi:10.1038/384078a0 · Cited by 1,613
Molecular and Cellular Mechanisms of Myocardial Stunning
Bolli, R., & Marbán, E. (1999) · Physiological Reviews · doi:10.1152/physrev.1999.79.2.609 · Cited by 1,051
Molecular and Cellular Mechanisms of Cardiac Arrhythmias
Keating, M. T., & Sanguinetti, M. C. (2001) · Cell · doi:10.1016/s0092-8674(01)00243-4 · Cited by 1,003
KCNQ1 Gain-of-Function Mutation in Familial Atrial Fibrillation
Chen, Y.-H., Xu, S.-J., Bendahhou, S., Wang, X.-L., Wang, Y., Xu, W.-Y., Jin, H., Sun, H., Su, X.-Y., Zhuang, Q.-N., et al. (2003) · Science · doi:10.1126/science.1077771 · Cited by 989
Modulation of A-type potassium channels by a family of calcium sensors
An, W., Bowlby, M. R., Betty, M., Cao, J., Ling, H., Mendoza, G., Hinson, J., Mattsson, K. I., Strassle, B. W., Trimmer, J. S., et al. (2000) · Nature · doi:10.1038/35000592 · Cited by 959
Electrophysiological remodeling in hypertrophy and heart failure
Tomaselli, G. F. (1999) · Cardiovascular Research · doi:10.1016/s0008-6363(99)00017-6 · Cited by 747
Potassium leak channels and the KCNK family of two-p-domain subunits
Goldstein, S. A. N., Böckenhauer, D., O'Kelly, I., & Zilberberg, N. (2001) · Nature reviews. Neuroscience · doi:10.1038/35058574 · Cited by 721
Conduction Slowing and Sudden Arrhythmic Death in Mice With Cardiac-Restricted Inactivation of Connexin43
Gutstein, D. E., Morley, G. E., Tamaddon, H. S., Vaidya, D. M., Schneider, M. D., Chen, J., Chien, K. R., Stuhlmann, H., & Fishman, G. I. (2001) · Circulation Research · doi:10.1161/01.res.88.3.333 · Cited by 680
A view of sur/KIR6.X, KATP channels.
Babenko, A. P., Aguilar-Bryan, L., & Bryan, J. (1998) · Annual Review of Physiology · doi:10.1146/annurev.physiol.60.1.667 · Cited by 533
Evidence for Two Components of Delayed Rectifier K + Current in Human Ventricular Myocytes
Li, G., Feng, J., Yue, L., Carrier, M., & Nattel, S. (1996) · Circulation Research · doi:10.1161/01.res.78.4.689 · Cited by 470
Role of the Kv4.3 K+Channel in Ventricular Muscle
Dixon, J. E., Shi, W., Wang, H., McDonald, C., Yu, H., Wymore, R. S., Cohen, I. S., & McKinnon, D. H. (1996) · Circulation Research · doi:10.1161/01.res.79.4.659 · Cited by 433
A Defect in the Kv Channel-Interacting Protein 2 (KChIP2) Gene Leads to a Complete Loss of Ito and Confers Susceptibility to Ventricular Tachycardia
Kuo, H.-C., Cheng, C., Clark, R. B., Lin, J. J., LIN, J. L.-C., Hoshijima, M., Nguyen-Tran, V. T. B., Gu, Y., Ikeda, Y., Chu, P., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00588-8 · Cited by 412
Inner Ear Defects Induced by Null Mutationof the isk Gene
Vetter, D. E., Mann, J. R., Wangemann, P., Liu, J., McLaughlin, K. J., Lesage, F., Marcus, D. C., Lazdunski, M., Heinemann, S. F., & Barhanin, J. (1996) · Neuron · doi:10.1016/s0896-6273(00)80255-x · Cited by 402
Four Kinetically Distinct Depolarization-activated K+ Currents in Adult Mouse Ventricular Myocytes
Xu, H., Guo, W., & Nerbonne, J. M. (1999) · The Journal of General Physiology · doi:10.1085/jgp.113.5.661 · Cited by 309
Self-citation
Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice
Lee, M. P., Ravenel, J. D., Hu, R.-J., Lustig, L. R., Tomaselli, G. F., Berger, R. D., Brandenburg, S. A., Litzi, T. J., Bunton, T. E., Limb, C. J., et al. (2000) · Journal of Clinical Investigation · doi:10.1172/jci10897 · Cited by 297
Functional Knockout of the Transient Outward Current, Long-QT Syndrome, and Cardiac Remodeling in Mice Expressing a Dominant-Negative Kv4 α Subunit
Barry, D. M., Xu, H., Schuessler, R. B., & Nerbonne, J. M. (1998) · Circulation Research · doi:10.1161/01.res.83.5.560 · Cited by 291
Self-citation
Regulation of KChIP2 potassium channel β subunit gene expression underlies the gradient of transient outward current in canine and human ventricle
Rosati, B., Pan, Z., Lypen, S., Wang, H., Cohen, I. S., Dixon, J. E., & McKinnon, D. H. (2001) · The Journal of Physiology · doi:10.1111/j.1469-7793.2001.0119b.x · Cited by 279
Inward Rectifiers in the Heart: An Update on IK1
Lopatin, A. N., & Nichols, C. G. (2001) · Journal of Molecular and Cellular Cardiology · doi:10.1006/jmcc.2001.1344 · Cited by 266
Targeted disruption of the Kcnq1 gene produces a mouse model of Jervell and Lange– Nielsen Syndrome
Casimiro, M. C., Knollmann, B. C., Ebert, S. N., Vary, J. C., Greene, A. E., Franz, M. R., Grinberg, A., Huang, S. P., & Pfeifer, K. E. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.041398998 · Cited by 260
Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome
Nuyens, D., Štengl, M., Dugarmaa, S., Rossenbacker, T., Compernolle, V., Rudy, Y., Smits, J. F. M., Flameng, W. J., Clancy, C. E., Moons, L., et al. (2001) · Nature Medicine · doi:10.1038/nm0901-1021 · Cited by 251
Genetic Manipulation of Cardiac K + Channel Function in Mice
Nerbonne, J. M., Nichols, C. G., Schwarz, T. L., & Escande, D. (2001) · Circulation Research · doi:10.1161/hh2301.100349 · Cited by 227
Self-citation
Myocardial Architecture and Ventricular Arrhythmogenesis
Peters, N. S., & Wit, A. L. (1998) · Circulation · doi:10.1161/01.cir.97.17.1746 · Cited by 220
Molecular basis of transient outward K+ current diversity in mouse ventricular myocytes
Guo, W., Xu, H., London, B., & Nerbonne, J. M. (1999) · The Journal of Physiology · doi:10.1111/j.1469-7793.1999.00587.x · Cited by 206
Self-citation
The role of myocardial gap junctions in electrical conduction and arrhythmogenesis
Kanno, S., & Saffitz, J. E. (2001) · Cardiovascular Pathology · doi:10.1016/s1054-8807(01)00078-3 · Cited by 203
Functional and Molecular Aspects of Voltage‐Gated K+ Channel β Subunits
Pongs, O., Leicher, T., BERGER, M., Roeper, J., Bähring, R., Wray, D., Giese, K.-P., Silva, A. J., & Storm, J. F. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb11296.x · Cited by 198
Replacement by Homologous Recombination of the minK Gene With lacZ Reveals Restriction of minK Expression to the Mouse Cardiac Conduction System
Kupershmidt, S., Yang, T., Anderson, M. E., Wessels, A., Niswender, K. D., Magnuson, M. A., & Roden, D. M. (1999) · Circulation Research · doi:10.1161/01.res.84.2.146 · Cited by 183
Enhanced Dispersion of Repolarization and Refractoriness in Transgenic Mouse Hearts Promotes Reentrant Ventricular Tachycardia
Baker, L. C., London, B., Choi, B., Koren, G., & Salama, G. (2000) · Circulation Research · doi:10.1161/01.res.86.4.396 · Cited by 176
Heterogeneous Expression of Gap Junction Channels in the Heart Leads to Conduction Defects and Ventricular Dysfunction
Gutstein, D. E., Morley, G. E., Vaidya, D. M., Liu, F., Chen, F. L., Stuhlmann, H., & Fishman, G. I. (2001) · Circulation · doi:10.1161/hc3601.093990 · Cited by 175
Long QT and ventricular arrhythmias in transgenic mice expressing the N terminus and first transmembrane segment of a voltage-gated potassium channel
London, B., Jeron, A., Zhou, J., Buckett, P. D., Han, X., Mitchell, G. F., & Koren, G. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.6.2926 · Cited by 173
Functional Consequences of Elimination of I to, f and I to, s
Guo, W., Li, H., London, B., & Nerbonne, J. M. (2000) · Circulation Research · doi:10.1161/01.res.87.1.73 · Cited by 167
Self-citation
Attenuation of the Slow Component of Delayed Rectification, Action Potential Prolongation, and Triggered Activity in Mice Expressing a Dominant-Negative Kv2 α Subunit
Xu, H., Barry, D. M., Li, H., Brunet, S., Guo, W., & Nerbonne, J. M. (1999) · Circulation Research · doi:10.1161/01.res.85.7.623 · Cited by 156
Self-citation
Role of Heteromultimers in the Generation of Myocardial Transient Outward K + Currents
Guo, W., Li, H., Aimond, F., Johns, D. C., Rhodes, K. J., Trimmer, J. S., & Nerbonne, J. M. (2002) · Circulation Research · doi:10.1161/01.res.0000012664.05949.e0 · Cited by 154
Self-citation
Involvement of IsK-Associated K + Channel in Heart Rate Control of Repolarization in a Murine Engineered Model of Jervell and Lange-Nielsen Syndrome
Drici, M., Arrighi, I., Chouabe, C., Mann, J. R., Lazdunski, M., Romey, G., & Barhanin, J. (1998) · Circulation Research · doi:10.1161/01.res.83.1.95 · Cited by 134
Cardiac Arrhythmias: From (Transgenic) Mice to Men
London, B. (2001) · Journal of Cardiovascular Electrophysiology · doi:10.1046/j.1540-8167.2001.01089.x · Cited by 123
Cloning and Expression of a Novel K+ Channel Regulatory Protein, KChAP
Wible, B. A., Yang, Q., Kuryshev, Y. A., Accili, E. A., & Brown, A. M. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.19.11745 · Cited by 121
The transient outward current in mice lacking the potassium channel gene Kv1.4
London, B., Wang, D. W., Hill, J. A., & Bennett, P. B. (1998) · The Journal of Physiology · doi:10.1111/j.1469-7793.1998.171bo.x · Cited by 115
A superfamily of small potassium channel subunits: form and function of the MinK-related peptides (MiRPs)
Abbott, G. W., & GOLDSTEIN, S. A. N. (1998) · Quarterly Reviews of Biophysics · doi:10.1017/s0033583599003467 · Cited by 115
Inhibition of Cardiac Delayed Rectifier K + Current by Overexpression of the Long-QT Syndrome HERG G628S Mutation in Transgenic Mice
Babij, P., Askew, G. R., Nieuwenhuijsen, B. W., Su, C.-M., Bridal, T. R., Jow, B., Argentieri, T. M., Kulik, J., DeGennaro, L. J., Spinelli, W., et al. (1998) · Circulation Research · doi:10.1161/01.res.83.6.668 · Cited by 115
Electrical Heterogeneity in the Heart: Physiological, Pharmacological and Clinical Implications
Antzelevitch, C. N., & Dumaine, R. (2002) · Comprehensive physiology · doi:10.1002/cphy.cp020117 · Cited by 113
Targeted Expression of a Dominant-Negative K v 4.2 K + Channel Subunit in the Mouse Heart
Wickenden, A. D., Lee, P. C., Sah, R., Huang, Q., Fishman, G. I., & Backx, P. H. (1999) · Circulation Research · doi:10.1161/01.res.85.11.1067 · Cited by 106
Targeted Replacement of Kv1.5 in the Mouse Leads to Loss of the 4-Aminopyridine–Sensitive Component of I K,slow and Resistance to Drug-Induced QT Prolongation
London, B., Guo, W., Pan, X.-H., Lee, J. S., Shusterman, V., Rocco, C. J., Logothetis, D. E., Nerbonne, J. M., & Hill, J. A. (2001) · Circulation Research · doi:10.1161/hh0901.090929 · Cited by 105
Self-citation
Concordant expression of KChIP2 mRNA, protein and transient outward current throughout the canine ventricle
Rosati, B., Grau, F. R., Rodriguez, S., Li, H., Nerbonne, J. M., & McKinnon, D. H. (2003) · The Journal of Physiology · doi:10.1111/j..2003.t01-1-00815.x · Cited by 103
Self-citation
Elimination of the transient outward current and action potential prolongation in mouse atrial myocytes expressing a dominant negative Kv4 α subunit
Xu, H., Li, H., & Nerbonne, J. M. (1999) · The Journal of Physiology · doi:10.1111/j.1469-7793.1999.0011o.x · Cited by 95
Self-citation
Effect of pacing and mexiletine on dispersion of repolarisation and arrhythmias in ΔKPQ SCN5A (long QT3) mice
Fabritz, L. (2003) · Cardiovascular Research · doi:10.1016/s0008-6363(02)00839-8 · Cited by 79
Heterogeneous Expression of Voltage‐Gated Potassium Channels in the Heart: Roles in Normal Excitation and Arrhythmias
Nerbonne, J. M., & Guo, W. (2002) · Journal of Cardiovascular Electrophysiology · doi:10.1046/j.1540-8167.2002.00406.x · Cited by 74
Self-citation
Transgenic mice overexpressing human KvLQT1 dominant-negative isoform Part I: Phenotypic characterisation
Demolombe, S. (2001) · Cardiovascular Research · doi:10.1016/s0008-6363(01)00231-0 · Cited by 69
Cardiac repolarization : bridging basic and clinical science
Gussak, I. B. (2003) · Humana Press eBooks · Cited by 61
Regional upregulation of Kv2.1-encoded current,I K,slow2, in Kv1DN mice is abolished by crossbreeding with Kv2DN mice
Zhou, J., Kodirov, S. A., Murata, M., Buckett, P. D., Nerbonne, J. M., & Koren, G. (2003) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00576.2002 · Cited by 61
Self-citation
Implications of ventricular arrhythmia vulnerability during murine electrophysiology studies
Maguire, C. T., Wakimoto, H., Patel, V. V., Hammer, P. E., Gauvreau, K., & Berul, C. I. (2003) · Physiological Genomics · doi:10.1152/physiolgenomics.00034.2003 · Cited by 58
Inducible polymorphic ventricular tachyarrhythmias in a transgenic mouse model with a long Q-T phenotype
Jeron, A., Mitchell, G. F., Zhou, J., Murata, M., London, B., Buckett, P. D., Wiviott, S. D., & Koren, G. (2000) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.2000.278.6.h1891 · Cited by 50
AdultKCNE1-Knockout Mice Exhibit a Mild Cardiac Cellular Phenotype
Charpentier, F., Mérot, J., Riochet, D., Marec, H. L., & Escande, D. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.9554 · Cited by 45
Characterization of mice with a combined suppression ofI to and I K,slow
Brunner, M. P., Guo, W., Mitchell, G. F., Buckett, P. D., Nerbonne, J. M., & Koren, G. (2001) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.2001.281.3.h1201 · Cited by 45
Self-citation
Remodeling the Cardiac Sarcomere Using Transgenesis
Robbins, J. M. (2000) · Annual Review of Physiology · doi:10.1146/annurev.physiol.62.1.261 · Cited by 42
Attenuation of IK,slow1 and IK,slow2 in Kv1/Kv2DN mice prolongs APD and QT intervals but does not suppress spontaneous or inducible arrhythmias
Kodirov, S. A., Brunner, M. P., Nerbonne, J. M., Buckett, P. D., Mitchell, G. F., & Koren, G. (2004) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00303.2003 · Cited by 36
Self-citation
Physiology and Molecular Biology of Ion Channels Contributing to Ventricular Repolarization
Nerbonne, J. M., & Kass, R. S. (2003) · Contemporary cardiology · doi:10.1007/978-1-59259-362-0_3 · Cited by 23
Self-citation
Sarcolemmal KATP Channels in the Heart: Molecular Mechanisms Brought to Light, but Physiologic Consequences Still in the Dark
Flagg, T. P., & Nichols, C. G. (2001) · Journal of Cardiovascular Electrophysiology · doi:10.1046/j.1540-8167.2001.01195.x · Cited by 13

Sorted by citations

Voltage-gated potassium channels as therapeutic targets
Wulff, H., Castle, N. A., & Pardo, L. A. (2009) · Nature Reviews Drug Discovery · doi:10.1038/nrd2983 · Cited by 810
Small and large animal models in cardiac contraction research: advantages and disadvantages
Milani-Nejad, N., & Janssen, P. M. L. (2014) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2013.10.007 · Cited by 484
Cardiomyocytes from human pluripotent stem cells: from laboratory curiosity to industrial biomedical platform
Denning, C., Borgdorff, V., Crutchley, J., Firth, K. S. A., George, V., Kalra, S., Kondrashov, A., Hoang, M. D., Mosqueira, D., Patel, A., et al. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2015.10.014 · Cited by 293
“associated with increased force of contraction in humans but decreased force in mice [17].”
Background
Zebrafish model for human long QT syndrome
Arnaout, R., Ferrer, T., Huisken, J., Spitzer, K. W., Stainier, D. Y. R., Tristani‐Firouzi, M., & Chi, N. C. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0702724104 · Cited by 240
Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling and Precision Medicine: A Scientific Statement From the American Heart Association
Musunuru, K., Sheikh, F., Gupta, R. M., Houser, S. R., Maher, K., Milan, D. J., Terzic, A., & Wu, J. C. (2018) · Circulation Genomic and Precision Medicine · doi:10.1161/hcg.0000000000000043 · Cited by 237

See all 175

Authors: Nerbonne, J.
Affiliations: Washington University in St. Louis (US)
Corresponding author: Nerbonne, J
ORCID: Nerbonne, J
Venue: Trends in Cardiovascular Medicine
Publisher: Elsevier BV
Published: 2004-04
Volume: 14
Issue: 3
Pages: 83-93
ISSN: 1050-1738 (ISSN-L)
DOI: 10.1016/j.tcm.2003.12.006
OpenAlex: W2039577288
Cited by: 175
References: 59
Citations by year: 2026: 2 · 2025: 5 · 2024: 4 · 2023: 9 · 2022: 4 · 2021: 14 · 2020: 9 · 2019: 7 · 2018: 11 · 2017: 9 · 2016: 13 · 2015: 7 · 2014: 13 · 2013: 8 · 2012: 13
FWCI: 4.61
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Trends in Cardiovascular Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ion channel regulation and function
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
Keywords: cardiac arrhythmias, mouse model, action potential, potassium channels, gap junctions, cardiac electrophysiology, cardiac conduction, repolarization, arrhythmia mechanisms, molecular genetics
MeSH terms: ERG1 Potassium Channel, Action Potentials, Animals, Arrhythmias, Cardiac, Disease Models, Animal, Heart, Heart Conduction System, Heart Ventricles, Humans, Long QT Syndrome, Mice, Transgenic, Potassium Channels, 4-Aminopyridine, Ventricular Function, Potassium Channels, Voltage-Gated, Potassium Channel Blockers, Myocytes, Cardiac, Mice, Ether-A-Go-Go Potassium Channels, KCNQ Potassium Channels, KCNQ1 Potassium Channel, Kv1.1 Potassium Channel, Shal Potassium Channels

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Studying Cardiac Arrhythmias in the Mouse—A Reasonable Model for Probing Mechanisms?

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks