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Cited by 67Acute Myocardial Infarction ResearchCannabis and Cannabinoid ResearchCardiac Health and Mental Health

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Marijuana use and acute myocardial infarction: A systematic review of published cases in the literature

Patel, Rikinkumar S., Kamil, Saher H., Bachu, Ramya, Adikey, Archana, Ravat, Virendrasinh, Kaur, Mandeep, Tankersley, William E., Goyal, Hemant·2020·Trends in Cardiovascular Medicine
DOI 10.1016/j.tcm.2019.08.003
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Abstract

Background and objective Marijuana use has gained popularity following legalization in the US. Marijuana can affect the heart through various mechanisms. This study aims to conduct a systematic review of published case reports of individuals with acute myocardial infarction (AMI) following marijuana use. Methods We conducted a systematic review of literature, including case reports, case series, and the letter to the editor on MEDLINE. Forty-six studies were included, with a total number of 62 patients with AMI and marijuana use. Results The mean age was 27.7 (±10.3) years with male predominance. About 3.7 g marijuana was used for an average of 9.7 years by the patients. From the cases reporting the onset of AMI symptoms, the average time was within 5 h after last marijuana use. The angiographic findings were normal in 36.8% of cases. In 42.1% of individuals, the left anterior descending coronary artery was occluded, making it the most common artery involved, followed by the right coronary artery (10.5%). Most cases were managed medically, followed by thrombectomy and stent placement, and percutaneous transluminal coronary angioplasty (PTCA). Complications included cardio-embolic stroke, and seven deaths were reported. Conclusion It is important to consider episodic marijuana use as a significant risk factor of AMI, particularly in individuals with no cardiac risk factors, as delay in management can result in fatal outcomes including increased risk of mortality.

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Metadata

Authors
Patel, R. S., Kamil, S. H., Bachu, R., Adikey, A., Ravat, V., Kaur, M., Tankersley, W. E., & Goyal, H.
Affiliations
  • Oklahoma Department of Mental Health and Substance Abuse Services (US)
  • Baptist Health Foundation (US)
  • Carilion Clinic (US)
  • Larkin Community Hospital (US)
  • American University of Antigua (AG)
  • The Wright Center for Graduate Medical Education (US)
Corresponding author
Goyal, Hemant
ORCID
Venue
Trends in Cardiovascular Medicine
Publisher
Elsevier BV
Published
2020-07
Volume
30
Issue
5
Pages
298-307
ISSN
1050-1738 (ISSN-L)
DOI
10.1016/j.tcm.2019.08.003
OpenAlex
W2967967032
Cited by
67
References
0
Citations by year
2026: 3 · 2025: 7 · 2024: 5 · 2023: 12 · 2022: 12 · 2021: 16 · 2020: 11
FWCI
1.81
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Trends in Cardiovascular Medicine (publishedVersion)
  • PubMed (publishedVersion)
Funders
International Business Machines Corporation
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
  • Health Sciences › Medicine › Pharmacology (medical) › Cannabis and Cannabinoid Research
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Keywords
cannabis use, acute myocardial infarction, cannabis, coronary artery occlusion, left anterior descending artery, percutaneous coronary intervention, thrombectomy, cardioembolic stroke, mortality, young adults
MeSH terms
Adolescent, Adult, Cannabinoids, Marijuana Abuse, Coronary Artery Disease, Female, Humans, Male, Marijuana Smoking, Middle Aged, Myocardial Infarction, Prognosis, Risk Factors, Risk Assessment, Young Adult

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