Gut barrier disruption and chronic disease

Over-the-counter mouthwash use, nitric oxide and hypertension risk

Joshipura, K., Muñoz-Torres, F., Fernández-Santiago, J., Patel, R. P., & Lopez-Candales, A. (2020) · Blood Pressure · doi:10.1080/08037051.2019.1680270 · Cited by 58

Intestinal Alkaline Phosphatase Attenuates Alcohol-Induced Hepatosteatosis in Mice

Hamarneh, S. R., Kim, B., Kaliannan, K., Morrison, S. A., Tantillo, T. J., Tao, Q., Mohamed, M. M. R., Ramirez, J. M., Karas, A., Liu, W., et al. (2017) · Digestive Diseases and Sciences · doi:10.1007/s10620-017-4576-0 · Cited by 57

Protective role of gut commensal microbes against intestinal infections

Yoon, M. Y., Lee, K., & Yoon, S. S. (2014) · The Journal of Microbiology · doi:10.1007/s12275-014-4655-2 · Cited by 56

Upregulation of Intestinal Barrier Function in Mice with DSS-Induced Colitis by a Defined Bacterial Consortium Is Associated with Expansion of IL-17A Producing Gamma Delta T Cells

Li, M., Wang, B., Sun, X., Tang, Y., Wei, X., Ge, B.-Y., Tang, Y., Deng, Y., He, C., Yuan, J., et al. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00824 · Cited by 52

Obesity: A New Adverse Effect of Antibiotics?

Fiol, F. D. S. D., Balcão, V. M., Barberato-Filho, S., Lopes, L. C., & Bergamaschi, C. D. C. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.01408 · Cited by 52

Yoghurts Containing Probiotics Reduce Disruption of the Small Intestinal Barrier in Methotrexate-Treated Rats

Southcott, E., Tooley, K. L., Howarth, G. S., Davidson, G. P., & Butler, R. N. (2008) · Digestive Diseases and Sciences · doi:10.1007/s10620-008-0275-1 · Cited by 51

Lubiprostone improves intestinal permeability in humans, a novel therapy for the leaky gut: A prospective randomized pilot study in healthy volunteers

Kato, T., Honda, Y., Kurita, Y., Iwasaki, A., Sato, T., Kessoku, T., Uchiyama, S., Ogawa, Y., Ohkubo, H., Higurashi, T., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0175626 · Cited by 50

Fiber: Effect on bacterial translocation and intestinal mucin content

Frankel, W. L., Zhang, W., Singh, A., et al. (1995) · World Journal of Surgery · doi:10.1007/bf00317001 · Cited by 47

Beyond the HLA Genes in Gluten-Related Disorders

Sallese, M., Lopetuso, L. R., Efthymakis, K., & Neri, M. (2020) · Frontiers in Nutrition · doi:10.3389/fnut.2020.575844 · Cited by 45

Endurance swimming stimulates transepithelial calcium transport and alters the expression of genes related to calcium absorption in the intestine of rats

Teerapornpuntakit, J., Dorkkam, N., Wongdee, K., Krishnamra, N., & Charoenphandhu, N. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90904.2008 · Cited by 44

Fish oil supplementation to a high-fat diet improves both intestinal health and the systemic obese phenotype

Monk, J. M., Liddle, D. M., Hutchinson, A. L., Wu, W., Lepp, D., David, W. L., Robinson, L. E., & Power, K. A. (2019) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2019.07.007 · Cited by 43

Effect of glutamine on change in early postoperative intestinal permeability and its relation to systemic inflammatory response

Quan, Z.-F. (2004) · World Journal of Gastroenterology · doi:10.3748/wjg.v10.i13.1992 · Cited by 42

Cannabidiol restores intestinal barrier dysfunction and inhibits the apoptotic process induced by Clostridium difficile toxin A in Caco‐2 cells

Gigli, S., Seguella, L., Pesce, M., Bruzzese, E., D’Alessandro, A., Cuomo, R., Steardo, L., Sarnelli, G., & Esposito, G. (2017) · United European Gastroenterology Journal · doi:10.1177/2050640617698622 · Cited by 42

Alteration in gut microbiota caused by time‐restricted feeding alleviate hepatic ischaemia reperfusion injury in mice

Ren, J., Hu, D., Mao, Y., Yang, H., Liao, W., Xu, W., Ge, P., Zhang, H., Sang, X., Lü, X., et al. (2018) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.14069 · Cited by 42

Gelatin tannate ameliorates acute colitis in mice by reinforcing mucus layer and modulating gut microbiota composition: Emerging role for ‘gut barrier protectors’ in IBD?

Scaldaferri, F., Lopetuso, L. R., Petito, V., Cufino, V., Bilotta, M., Arena, V., Stigliano, E., Maulucci, G., Papi, M., Caristo, M. E., et al. (2014) · United European Gastroenterology Journal · doi:10.1177/2050640614520867 · Cited by 41

Sucrose Co-administration Reduces the Toxic Effect of Lectin on Gut Permeability and Intestinal Bacterial Colonization

Ramadass, B., Dokładny, K., Moseley, P. L., et al. (2010) · Digestive Diseases and Sciences · doi:10.1007/s10620-010-1359-2 · Cited by 38

Intakes of Vitamin B6 and Dietary Fiber and Clinical Course of Systemic Lupus Erythematosus: A Prospective Study of Japanese Female Patients

Minami, Y., Hirabayashi, Y., Nagata, C., Ishii, T., Harigae, H., & Sasaki, T. (2011) · Journal of Epidemiology · doi:10.2188/jea.je20100157 · Cited by 36

Zinc treatment is efficient against Escherichia coli α-haemolysin-induced intestinal leakage in mice

Wiegand, S., Zakrzewski, S. S., Eichner, M., Schulz, E., Günzel, D., Pieper, R., Rosenthal, R., Barmeyer, C., Bleich, A., Dobrindt, U., et al. (2017) · Scientific Reports · doi:10.1038/srep45649 · Cited by 36

Serum endotoxin, gut permeability and skeletal muscle metabolic adaptations following a short term high fat diet in humans

Bowser, S. M., McMillan, R. P., Boutagy, N. E., Tarpey, M. D., Smithson, A. T., Osterberg, K. L., Neilson, A. P., Davy, B. M., Davy, K. P., & Hulver, M. W. (2019) · Metabolism · doi:10.1016/j.metabol.2019.154041 · Cited by 36

Rebamipide suppresses diclofenac-induced intestinal permeabilityviamitochondrial protection in mice

Diao, L. (2012) · World Journal of Gastroenterology · doi:10.3748/wjg.v18.i10.1059 · Cited by 35

Enteral feeding decreases gut apoptosis, permeability, and lung inflammation during murine endotoxemia

Alscher, K. T., Phang, P. T., McDonald, T., & Walley, K. R. (2001) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.2001.281.2.g569 · Cited by 34

Modulations of Food-derived Substances on Intestinal Permeability in Caco-2 Cell Monolayers

KONISHI, Y. (2003) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.67.2297 · Cited by 30

Protective Role of p70S6K in Intestinal Ischemia/Reperfusion Injury in Mice

Ban, K., & Kozar, R. A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0041584 · Cited by 30

Hypoxia‐induced intestinal barrier changes in balloon‐assisted enteroscopy

Lee, T., Huang, Y., Lu, Y., Yeh, Y., & Yu, L. C. (2017) · The Journal of Physiology · doi:10.1113/jp275277 · Cited by 29

Survival of Mice with Gastrointestinal Acute Radiation Syndrome through Control of Bacterial Translocation

Suzuki, F., Loucas, B. D., Ito, I., Asai, A., Suzuki, S., & Kobayashi, M. (2018) · The Journal of Immunology · doi:10.4049/jimmunol.1701515 · Cited by 29

A glance at … dietary emulsifiers, the human intestinal mucus and microbiome, and dietary fiber

Glade, M. J., & Meguid, M. M. (2015) · Nutrition · doi:10.1016/j.nut.2015.12.036 · Cited by 28

Lubiprostone as a potential therapeutic agent to improve intestinal permeability and prevent the development of atherosclerosis in apolipoprotein E-deficient mice

Arakawa, K., Ishigami, T., Nakai-Sugiyama, M., Chen, L., Doi, H., Kino, T., Minegishi, S., Saigoh-Teranaka, S., Nakashima-Sasaki, R., Hibi, K., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0218096 · Cited by 28

Effects of Mesalamine Treatment on Gut Barrier Integrity After Burn Injury

Cannon, A. R., Akhtar, S., Hammer, A. M., Morris, N. L., Javorski, M. J., Li, X., Kennedy, R. H., Gamelli, R. L., & Choudhry, M. A. (2016) · Journal of Burn Care & Research · doi:10.1097/bcr.0000000000000396 · Cited by 27

Targeted Intestinal Tight Junction Hyperpermeability Alters the Microbiome, Behavior, and Visceromotor Responses

Inczefi, O., Bacquie, V., Olier, M., Rincel, M., Ringot-Destrez, B., Ellero‐Simatos, S., Eutamène, H., Bétoulières, C., Thomas, J., Lainé, J., et al. (2020) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2020.02.008 · Cited by 21

Ascorbic Acid may Exacerbate Aspirin‐Induced Increase in Intestinal Permeability

Sequeira, I. R., Kruger, M. C., Hurst, R. D., & Lentle, R. G. (2015) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.12388 · Cited by 12

Post-injury vagal nerve stimulation protects against intestinal epithelial barrier breakdown

Krzyżaniak, M., Peterson, C. Y., Reys, L. G., et al. (2010) · Journal of the American College of Surgeons · doi:10.1016/j.jamcollsurg.2010.06.118 · Cited by 9

Signalling cognition: The gut microbiota and hypothalamic-pituitary-adrenal axis

Rusch, J. A., Layden, B. T., & Dugas, L. R. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1130689 · Cited by 415

Immunopathogenic mechanisms and immunoregulatory therapies in MASLD

He, Y., Chen, Y., Qian, S., van Der Merwe, S., Dhar, D., Brenner, D. A., & Tacke, F. (2025) · Cellular & Molecular Immunology · doi:10.1038/s41423-025-01307-5 · Cited by 81

Gut hormones in microbiota-gut-brain cross-talk

Sun, L.-J., Li, J.-N., & Nie, Y.-Z. (2020) · Chinese Medical Journal · doi:10.1097/cm9.0000000000000706 · Cited by 145

Quercetin improves gut dysbiosis in antibiotic-treated mice

Shi, T., Bian, X., Yao, Z., Wang, Y., Gao, W., & Guo, C. (2020) · Food & Function · doi:10.1039/d0fo01439g · Cited by 132

Gut microbiota dysbiosis in rats with LPS-induced liver diseases affected by Aronia melanocarpa polyphenols

Kong, Y., Li, D., & Meng, X. (2023) · Food Science and Technology · doi:10.5327/fst.130622 · Cited by 1

Metagenomic and metabolomic analyses unveil dysbiosis of gut microbiota in chronic heart failure patients

Cui, X., Ye, L., Li, J., Jin, L., Wang, W., Li, S., Bao, M., Wu, S., Li, L., Geng, B., et al. (2018) · Scientific Reports · doi:10.1038/s41598-017-18756-2 · Cited by 380

The potential of human milk oligosaccharides to impact the microbiota-gut-brain axis through modulation of the gut microbiota

Al-Khafaji, A. H., Jepsen, S. D., Christensen, K. R., & Vigsnæs, L. K. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2020.104176 · Cited by 62