The problem of biogenic amines in fermented foods and the use of potential biogenic amine-degrading microorganisms as a solution
Open accessAbstract
Biogenic amines (BA) are low-molecular-weight nitrogenous organic bases, which can accumulate in high concentration in food due to microbial activity and cause toxic effects in consumers. In some fermented foods it is difficult to prevent the accumulation of BA since the microbiological/chemical/physical conditions of the fermentation can not be easily modified. An alternative in such cases is the use of food microorganisms that are able to degrade BA once they have been synthesized in the food matrix. In this review, we examine the microorganisms that have demonstrated the ability to degrade BA and their technological relevance in fermented foods.
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Biogenic amines are generated through enzymatic decarboxylation of free amino acids; their accumulation in fermented matrices can trigger toxicological responses including hypertensive crises, migraines, and pseudo-allergic reactions.
“Bas (such as histamine, tyramine, and putrescine) are generated through the enzymatic decarboxylation of free amino acids. The accumulation of these vasoactive and psychoactive nitrogenous compounds in fermented matrices can trigger severe toxicological responses upon ingestion, including hypertensive crises, intense migraines, and pseudo-allergic reactions (Alvarez-MA et al., 2014).”
From Probiotic potential of Lactobacillus acidophilus TMPC 41127 isolated from traditional cheese in inhibiting Salmonella Typhi biofilms and virulence genes (2026) · cites this paper as Alvarez-MA et al., 2014
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References 88 · Cited by 384
- Authors
- Alvarez, M. A., & Moreno-Arribas, M. V.
- Venue
- Trends in Food Science & Technology
- Publisher
- Elsevier BV
- Published
- 2014-10
- Volume
- 39
- Issue
- 2
- Pages
- 146-155
- ISSN
- 0924-2244 (ISSN-L)
- OpenAlex
- W2010978022
- Cited by
- 384
- References
- 88
- Citations by year
- 2026: 19 · 2025: 40 · 2024: 43 · 2023: 37 · 2022: 45 · 2021: 47 · 2020: 39 · 2019: 38 · 2018: 26 · 2017: 17 · 2016: 24 · 2015: 8 · 2014: 1
- FWCI
- 6.83
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- Trends in Food Science & Technology (publishedVersion)
- DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion, other-oa)
- Funders
- Ministerio de Economía y Competitividad (AGL2012-40172-C02-01, AGL2010-18430, PRI-PIBAR-2011-1358)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Polyamine Metabolism and Applications
- Life Sciences › Agricultural and Biological Sciences › Food Science › Fermentation and Sensory Analysis
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Keywords
- biogenic amines, fermented foods, biogenic amine degradation, food spoilage, food safety
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