Cited by 81Protein Hydrolysis and Bioactive PeptidesSeaweed-derived Bioactive CompoundsFood Industry and Aquatic Biology

Macroalgal-derived protein hydrolysates and bioactive peptides: Enzymatic release and potential health enhancing properties

Pimentel, Filipa B., Alves, Rita C., Harnedy, Pádraigín A., FitzGerald, Richard J., Oliveira, M. Beatriz P.P.·2019·Trends in Food Science & Technology

Abstract

Macroalgae are a natural source of valuable compounds for different applications. Despite the high protein content (up to 47%) and complete essential amino acid profile in some species, their protein fraction is still relatively underexplored. Besides the potential as alternative protein sources, macroalgae can also provide bioactive peptides and other proteinaceous compounds with biological value.In this review, data associated with macroalgal nitrogenous components, particularly peptides and protein hydrolysates, are presented and discussed, especially regarding their potential health properties and methodologies employed to obtain and isolate them.Obtaining these compounds and assessing their biological activities involves a combination of preparation and analytical steps (e.g. isolation, purification, detection and quantification). Hydrolysis of macroalgal proteins using different proteinases generates multiple peptides with a broad range of biological activities. Further research and innovation will allow the development of more efficient production processes and will improve the range of applications. Current scientific evidences regarding the potential health benefits of macroalgae-derived proteinaceous compounds highlight the need of additional investments to effectively transfer promising findings into market driven opportunities.

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Crossref · 10.1016/j.tifs.2019.09.006

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References 116 · Cited by 81

Authors
Pimentel, F. B., Alves, R. C., Harnedy, P. A., FitzGerald, R. J., & Oliveira, M. B. P. P.
Affiliations
  • Universidade do Porto (PT)
  • University of Limerick (IE)
Corresponding author
Alves, Rita C.
Venue
Trends in Food Science & Technology
Publisher
Elsevier BV
Published
2019-11
Volume
93
Pages
106-124
ISSN
0924-2244 (ISSN-L)
OpenAlex
W2972248217
Cited by
81
References
116
Citations by year
2026: 7 · 2025: 15 · 2024: 15 · 2023: 11 · 2022: 10 · 2021: 15 · 2020: 8
FWCI
2.74
Type
journal article
Language
en
Open access
closed
Locations
Trends in Food Science & Technology (publishedVersion)
Funders
  • Ministério da Ciência, Tecnologia e Ensino Superior
  • Fundação para a Ciência e a Tecnologia (UID/QUI/50006/2019, SFRH/BD/109042/2015)
  • Marine Institute
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Hydrolysis and Bioactive Peptides
  • Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Food Industry and Aquatic Biology
Keywords
seaweed, protein hydrolysates, bioactive peptides, enzymatic hydrolysis, proteolytic enzymes, alternative protein sources, health benefits, peptide purification, nitrogen compounds, functional food ingredients

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