Brain Pericytes As Mediators of Neuroinflammation

Rustenhoven, Justin, Jansson, Deidre, Smyth, Leon C., Dragunow, Mike·2017·Trends in Pharmacological Sciences
DOI 10.1016/j.tips.2016.12.001

Cited by (375)

Items 301–375 of 375

  1. Astrocyte alterations during Osmotic Demyelination Syndrome: intermediate filaments, aggresomes, proteasomes, and glycogen storages
    Jacques Gilloteaux, Corry Charlier, Valérie Suain, Charles Nicaise · 2025 · Ultrastructural Pathology
  2. The role of pericytes in glaucoma and their potential as drug targets
    Taher K. Eleiwa, Abdelrahman M. Elhusseiny, Reem H. ElSheikh, Saige Oechsli, Achyut J. Raghavendra, Zhuolin Liu, Daniel X. Hammer, Osamah J. Saeedi · 2025 · Expert Review of Ophthalmology
  3. Memory-enhancing food-derived peptides: action and transportability
    Lihong Cheng, T. Matsui · 2026 · Food Science and Technology Research
  4. Friend or foe? Glial–vascular interactions in health and neurodegenerative disease
    Conor McQuaid, Michael D.E. Sewell, Axel Montagne · 2026 · Pharmacological Reviews
  5. Double‐Stranded DNA Sensing cGAS‐STING Immune Signaling in a Rat Co‐Culture Model of the Blood–Brain Barrier
    András Harazin, Line Sinnathamby Reinert, Parvez Alam, Lea Hoy, Annemette Boe Marnow, J L Nielsen, Anna Lorentzen, Daniel E. Otzen, Søren R. Paludan, Morten Schallburg Nielsen · 2026 · Cell Biochemistry and Function
  6. A role for pericytes in chronic pain?
    Alexandra Margaret Durrant, Matthew N. Swift, Nicholas Beazley‐Long · 2018 · Current Opinion in Supportive and Palliative Care
  7. Autophagy Monitoring in Cerebral Pericytes from Alzheimer’s disease Mouse Model in an Inflammatory Environment
    P Guylène · 2022 · Journal of Parkinson’s Disease and Alzheimer’s Disease
  8. Targeting the Blood-Brain Barrier with Nano-Biomaterials
    Sanjay Kulle Gowda, Dongala Venkataramanamma, Rina Singh · 2024 · Springer eBooks
  9. Screening Activity of Brain Cancer-Derived Factors on Primary Human Brain Pericytes
    Samuel JC McCullough, Eliene Albers, Akshata Anchan, Jane J. Yu, Bronwen J. Connor, E. Scott Graham · 2024 · Onco
  10. The Central and Peripheral Nervous System Immunological Compartments in Health and Disease
    Vanessa Beynon, Radhika Raheja, Maria Antonietta Mazzola, Howard L. Weiner · 2019 · Springer eBooks
  11. In Vivo Optical Imaging and Manipulation of Brain Pericytes
    Andrée‐Anne Berthiaume, Vanessa Coelho‐Santos, David A. Hartmann, Andy Y. Shih · 2021 · Stem cell biology and regenerative medicine
  12. Pathomorphological changes of capillaries in the cerebral cortex in type 2 diabetes mellitus
    Valerii Tumanskyi, Yu. M. Avramenko · 2021 · Current issues in pharmacy and medicine science and practice
  13. Pericytes mediate neurovascular remodeling in chronic arterial hypertension
    Lorena Morton, Alejandra P. Garza, Grażyna Dębska–Vielhaber, Luis E. Villafuerte, Solveig Henneicke, Philipp Arndt, Sven Guenther Meuth, Stefanie Schreiber, Ildikò Rita Dunay · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  14. Developing a neural implant to enable controlled alterations to brain architecture
    Nick Weir · 2019 · Nottingham Trent University's Institutional Repository (Nottingham Trent Repository)
  15. Thrombosis-on-a-chip
    H.J. Albers · 2020
  16. Selective Regional Isolation of Brain Microvessels
    Fernanda Medina‐Flores, Gabriela Hurtado‐Alvarado, Beatriz Gómez‐González · 2020 · Methods in molecular biology
  17. Inflammatory Mediators Released by Brain Pericytes as Sensors and Effectors in Blood-Brain Barrier Dysfunction
    Shinya Dohgu, Fuyuko Takata, Yasufumi Kataoka · 2021 · Stem cell biology and regenerative medicine
  18. Effects of Cytomegalovirus on Pericytes
    Donald J. Alcendor · 2021 · Stem cell biology and regenerative medicine
  19. TLR-4 Signaling in Pericytes
    Alessandra Stasi, Rossana Franzin, Giuseppe Stefano Netti, Elena Ranieri, Loreto Gesualdo, Giovanni Stallone, Giuseppe Castellano · 2021 · Stem cell biology and regenerative medicine
  20. Chaperone-mediated autophagy—mechanisms and disease role
    Amelina Albornoz, Álvaro Sequeida, Christian Rodríguez, Mauricio Budini · 2021 · Elsevier eBooks
  21. Alterations in the junctions between brain endothelial cells and pericytes during chronic sleep restriction
    María Fernanda Medina Flores · 2019
  22. Pattern recognition receptors and inflammasome activation in the blood-brain barrier
    Ádám Nyúl‐Tóth · 2018
  23. Pericyte loss impairs BBB and cognitive function in aged mice after anesthesia/surgery
    Hui Yuan, Daofan Sun, Yiqin Ji, Bo Meng, Bo Lu, Rongjun Liu, Xiuzhong Xing, Ruichun Wang, Junping Chen · 2023 · Research Square
  24. Pattern Recognition Receptors in Brain: Emphasis on Toll Like Receptors and their Types
    Jayalakshmi Krishnan · 2023 · BENTHAM SCIENCE PUBLISHERS eBooks
  25. Long-term alcohol exposure aggravates ischemic stroke-induced damage by promoting pericyte NLRP3 inflammasome activation via the TLR4/NF-κB pathway in rats
    Kaixin Wang, Lingfei Yang, Qingsheng Li, Xuan Yang, Ziyi Chen, Yudi Xu, Yufei Chen, Yanjie Jia, Zhe Gong · 2023 · Research Square
  26. Neural crest mural cells of forebrain meninges harbor innate immune functions during early brain development and exhibit different responses to septic and toxic insults
    Diego Amarante-Silva, Emmanuel Bruet, Rémy Gars, Margaux Piechon, Tatiana Gorojankina, Jerome S. Bignon, Sophie Creuzet · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  27. Research of Immune Cells in Neural Function Repair after Ischemic Stroke
    雪娟 郭 · 2024 · Advances in Clinical Medicine
  28. Human iPSC-derived brain pericytes exhibit differences in inflammatory activation compared to primary human brain pericytes
    Samuel JC McCullough, Eliene Albers, Akshata Anchan, Jane J. Yu, Simon J. O’Carroll, Bronwen J. Connor, E. Scott Graham · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  29. A Novel Mouse Model Demonstrates In Vivo Replenishment of Central Nervous System Pericytes After Successful Acute Ablation
    Dila Atak, Erdost Yıldız, Esra Özkan, Mohammadreza Yousefi, Ayşe Özkan, Aysu Bilge Gökyüzü, Ali Burak Kızılırmak, Iman Asaad Alnajjar, Çiçek Kanar, Zeynep Lal Caan et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  30. Cerebrospinal fluid platelet-derived growth factor receptor-beta is negatively correlated with depressive symptom severity in suicide attempters
    A Bonţidean, Daniel Lindqvist, Cécile Grudet, Lil Träskman‐Bendz, Lena Brundin, Filip Ventorp · 2025 · Journal of Affective Disorders Reports
  31. Generation of a Three-dimensional Human Neurovascular Unit Model in a Microfluidic Chip
    Boning Qiu, Sara Pompe, Katerina T. Xenaki, Paul M.P. van Bergen en Henegouwen, Sabrina Oliveira, Enrico Mastrobattista, Massimiliano Caiazzo · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  32. The Blood-Brain Barrier Disruption Methods for Drug Delivery
    Misha Amini, Matei A. Banu · 2025 · Springer eBooks
  33. Unveiling Central Nervous System Pericytes: Immunofluorescence Protocol and Confocal Microscopy
    Antonio d’Amati, Doménico Ribatti, Daniela Virgintino, Mariella Errede · 2025 · Methods in molecular biology
  34. Function and Plasticity of Microvascular Pericytes
    Ariana Diandra Suarez‐Martinez, Anthony C. Bruce, Ramon Castellanos-Sanchez, Tien Comlekoglu, David J. Csordas, Lilly DeCostanza, Kareem El‐Ghazawi, Julie Leonard‐Duke, Corrina Peachey, Daisy Zhu et al. · 2025 · Physiology in health and disease
  35. Additional file 1 of Characterization and oncolytic virus targeting of FAP-expressing tumor-associated pericytes in glioblastoma
    Li, Ming, Li, Guoping, Kiyokawa, Juri, Zain A. Tirmizi, Leland G. Richardson, Ning, Jianfang, Das, Saumya, Martuza, Robert L., Stemmer-Rachamimov, Anat, Samuel D. Rabkin et al. · 2020 · Figshare
  36. Additional file of Neural crest cell-derived pericytes act as pro-angiogenic cells in human neocortex development and gliomas
    Girolamo, Francesco, Ignazio de Trizio, Mariella Errede, Giovanna Longo, Antonio d’Amati, Daniela Virgintino · 2021 · Figshare
  37. Additional file 1 of Pericytes as mediators of infiltration of macrophages in multiple sclerosis
    Deepak K. Kaushik, Bhattacharya, Anindita, Brian Mark Lozinski, Wee Yong, V. · 2021 · Figshare
  38. Additional file 4 of Pericytes are protective in experimental pneumococcal meningitis through regulating leukocyte infiltration and blood–brain barrier function
    Nina C. Teske, Susanne Dyckhoff-Shen, Paul Beckenbauer, Jan Philipp Bewersdorf, Joo-Yeon Engelen-Lee, Hammerschmidt, Sven, Roland E. Kälin, Pfister, Hans-Walter, Matthijs C. Brouwer, Matthias Klein et al. · 2024 · Figshare
  39. Additional file 1 of Amyloid β oligomer induces cerebral vasculopathy via pericyte-mediated endothelial dysfunction
    Chen, Siqi, Daji Guo, Yuanyuan Zhu, Xiao, Songhua, Jiatian Xie, Zhang, Zhan, Hu, Yu, Jialin Huang, Xueying Ma, Ning, Zhiyuan et al. · 2024 · Figshare
  40. Additional file 2 of Amyloid β oligomer induces cerebral vasculopathy via pericyte-mediated endothelial dysfunction
    Chen, Siqi, Daji Guo, Yuanyuan Zhu, Xiao, Songhua, Jiatian Xie, Zhan Zhang, Hu, Yu, Jialin Huang, Xueying Ma, Ning, Zhiyuan et al. · 2024 · Figshare
  41. Additional file 1 of Transcriptomic signatures of individual cell types in cerebral cavernous malformation
    Ying Li, Romuald Girard, Abhinav Srinath, Diana Vera Cruz, Cezary Ciszewski, Chang Chen, Rhonda Lightle, Sharbel G. Romanos, Je Yeong Sone, Thomas Moore et al. · 2024 · Figshare
  42. Additional file 3 of Pericytes are protective in experimental pneumococcal meningitis through regulating leukocyte infiltration and blood–brain barrier function
    Nina C. Teske, Susanne Dyckhoff-Shen, Paul Beckenbauer, Jan Philipp Bewersdorf, Joo-Yeon Engelen-Lee, Hammerschmidt, Sven, Roland E. Kälin, Pfister, Hans-Walter, Matthijs C. Brouwer, Matthias Klein et al. · 2024 · Figshare
  43. Additional file 1 of Pericytes are protective in experimental pneumococcal meningitis through regulating leukocyte infiltration and blood–brain barrier function
    Nina C. Teske, Susanne Dyckhoff-Shen, Paul Beckenbauer, Jan Philipp Bewersdorf, Joo-Yeon Engelen-Lee, Hammerschmidt, Sven, Roland E. Kälin, Pfister, Hans-Walter, Matthijs C. Brouwer, Matthias Klein et al. · 2023 · Figshare
  44. Additional file 2 of High-fat diet-induced diabetes leads to vascular alterations, pericyte reduction, and perivascular depletion of microglia in a 6-OHDA toxin model of Parkinson disease
    Osama F. Elabi, João Paulo Monteiro Carvalho Móri da Cunha, Abderahim Gaceb, Malin Fex, Gesine Paul · 2021 · Figshare
  45. Additional file 5 of Pericytes are protective in experimental pneumococcal meningitis through regulating leukocyte infiltration and blood–brain barrier function
    Nina C. Teske, Susanne Dyckhoff-Shen, Paul Beckenbauer, Jan Philipp Bewersdorf, Joo-Yeon Engelen-Lee, Hammerschmidt, Sven, Roland E. Kälin, Pfister, Hans-Walter, Matthijs C. Brouwer, Klein, Matthias et al. · 2024 · Figshare
  46. Additional file 4 of Amyloid β oligomer induces cerebral vasculopathy via pericyte-mediated endothelial dysfunction
    Siqi Chen, Daji Guo, Yuanyuan Zhu, Xiao, Songhua, Jiatian Xie, Zhang, Zhan, Yu Hu, Jialin Huang, Xueying Ma, Ning, Zhiyuan et al. · 2024 · Figshare
  47. Additional file 1 of High-fat diet-induced diabetes leads to vascular alterations, pericyte reduction, and perivascular depletion of microglia in a 6-OHDA toxin model of Parkinson disease
    Osama F. Elabi, João Paulo Monteiro Carvalho Móri da Cunha, Abderahim Gaceb, Malin Fex, Gesine Paul · 2021 · Figshare
  48. Additional file 6 of Pericytes are protective in experimental pneumococcal meningitis through regulating leukocyte infiltration and blood–brain barrier function
    Nina C. Teske, Susanne Dyckhoff-Shen, Paul Beckenbauer, Jan Philipp Bewersdorf, Joo-Yeon Engelen-Lee, Hammerschmidt, Sven, Roland E. Kälin, Pfister, Hans-Walter, Matthijs C. Brouwer, Matthias Klein et al. · 2024 · Figshare
  49. Additional file 2 of Transcriptomic signatures of individual cell types in cerebral cavernous malformation
    Ying Li, Romuald Girard, Abhinav Srinath, Diana Vera Cruz, Cezary Ciszewski, Chang Chen, Rhonda Lightle, Sharbel G. Romanos, Je Yeong Sone, Thomas Moore et al. · 2024 · Figshare
  50. Additional file 3 of High-fat diet-induced diabetes leads to vascular alterations, pericyte reduction, and perivascular depletion of microglia in a 6-OHDA toxin model of Parkinson disease
    Osama F. Elabi, João Paulo Monteiro Carvalho Móri da Cunha, Abderahim Gaceb, Malin Fex, Gesine Paul · 2021 · Figshare
  51. Additional file 1 of Platelet-derived growth factor signaling in pericytes promotes hypothalamic inflammation and obesity
    Akira Okekawa, Wada, Tsutomu, Yasuhiro Onogi, Takeda, Yuki, Yuichiro Miyazawa, Masakiyo Sasahara, Hiroshi Tsuneki, Toshiyasu Sasaoka · 2024 · Figshare
  52. Additional file 2 of Pericytes are protective in experimental pneumococcal meningitis through regulating leukocyte infiltration and blood–brain barrier function
    Nina C. Teske, Susanne Dyckhoff-Shen, Paul Beckenbauer, Jan Philipp Bewersdorf, Joo-Yeon Engelen-Lee, Hammerschmidt, Sven, Roland E. Kälin, Pfister, Hans-Walter, Matthijs C. Brouwer, Matthias Klein et al. · 2024 · Figshare
  53. Additional file 1 of Serum biomarkers of neuroinflammation and blood-brain barrier leakage in amyotrophic lateral sclerosis
    Maize C. Cao, Erin E. Cawston, Grace Xia Chen, Collin Brooks, Jeroen E. Douwes, Dave McLean, E. Scott Graham, Dragunow, Mike, Emma L. Scotter · 2022 · Figshare
  54. Additional file 3 of Amyloid β oligomer induces cerebral vasculopathy via pericyte-mediated endothelial dysfunction
    Siqi Chen, Daji Guo, Yuanyuan Zhu, Xiao, Songhua, Jiatian Xie, Zhan Zhang, Hu, Yu, Jialin Huang, Xueying Ma, Ning, Zhiyuan et al. · 2024 · Figshare
  55. Microglial Activation in Cerebrovascular Accidents and the Manifestation of Major Depressive Disorder: A Comprehensive Review
    Karla Cristina Razón-Hernández, Gabriela Martínez-Ramírez, Javier Villafranco, Óscar Rodríguez-Barreto, Daniel Ortuño‐Sahagún, Roxana Magaña-Maldonado, Karla Sánchez-Huerta, Enrique Becerril‐Villanueva, Lenin Pavón, Enrique Estudillo et al. · 2025 · Brain Sciences
  56. Postoperative neurocognitive disorder: migration and crosstalk of inflammation in the peripheral and central nervous system
    Xinyi Chen, Wanqiu Yu, Zhaoqiong Zhu · 2026 · Perioperative Medicine
  57. Central nervous system pericytes express soluble ST2 in inflammation and injury
    Deidre Jansson, Blake Highet, Susan Li, Taylor J. Stevenson, Leon C. D. Smyth, Justin Rustenhoven, Sheryl Xia Feng, Richard Daneman, Cayce Dorrier, Andrew N. Clarkson et al. · 2026 · Molecular Brain
  58. Mechanisms of blood-brain barrier penetration: A molecular dynamics study on R9 and MPG peptide translocation
    Cíntia Emi Yanaguibashi Leal, Nicola D’Amelio, Benjamin Bouvier · 2026 · Biochimica et Biophysica Acta (BBA) - Biomembranes
  59. Développement d'anticorps à domaine unique comme vecteurs ciblant des récepteurs impliqués dans la transcytose et traversant la barrière hémato-encéphalique pour l'adressage d'agents d'imagerie et thérapeutiques vers le cerveau
    Romy Cohen · 2018
  60. Rôle de la neuroinflammation et du récepteur microglial TREM2 dans la progression de deux modèles de tauopathie
    Audrey Vautheny · 2019 · theses.fr (ABES)
  61. Neurovascular unit changes after juvenile traumatic brain injury
    Aleksandra Ichkova · 2019 · theses.fr (ABES)
  62. In-depth cellular and molecular characterization of neuroinflammation in epilepsy and its potential resolution by the use of mesenchymal stem cells
    Nadia Gasmi · 2020 · theses.fr (ABES)
  63. Etude du neurotropisme de deux arbovirus émergents : les virus Zika et Usutu
    Marion Clé · 2020 · theses.fr (ABES)
  64. Miniaturization and automation of a well-established human in vitro blood-brain barrier model, and the use of these models to evaluate nanoparticles mechanisms of transport
    Elisa L. J. Moya · 2021 · theses.fr (ABES)
  65. Impact du TNF alpha sur les métabolismes du cholestérol et des peptides AB au niveau des péricytes cérébraux humains
    Shiraz Dib · 2023 · theses.fr (ABES)
  66. Role of perivascular macrophages in a new experimental model of intracerebral aneurysms
    Martina Glavan · 2022 · theses.fr (ABES)
  67. Mechanisms of Pericyte‐Mediated Cancer Metastasis
    Ziheng Guo, Yihai Cao · 2026 · Advanced Science
  68. ULTRASTRUCTURAL CHANGES OF HEMOCAPILLARIES IN THE CEREBRAL CORTEX OF WHITE RATS UNDER EXPERIMENTAL ONCOGENESIS
    O. R. Nebesnyi, I. M. Ivanchuk, O. I. Hrymalyuk, L. D. Tupol, З. М. Небесна · 2026 · Bulletin of Problems Biology and Medicine
  69. Brain-targeted delivery of messenger RNA drugs: Overcoming barriers and accelerating therapeutic breakthroughs
    Yu Zeng, Tingting Song, S Liu, Xiaman Liao, Mo Hu, H Yang, Shaofei He, Xiangrong Song · 2026 · Chinese Medical Journal BioMed
  70. Insights into the blood–brain barrier in mental health disorders: from experimental models to clinical findings
    Maria Grazia Ferraro, Adrien Stanley, Pellegrino Lippiello, Silvia Pascarella, Luisa Speranza, Mariateresa Ricci, Floriana Volpicelli, Sergio Chieffi, Maria Concetta Miniaci · 2026 · Reviews in the Neurosciences
  71. Deletion of RGS5 attenuates high-fat diet-induced cerebrovascular pathology and associated spatial memory deficits
    Osama F. Elabi, Shubhangini Tiwari, Alba M. García-Serrano, R. Carlsson, Carlos Noriega Polo, Luis Arturo Fonseca-Fonseca, João M. N. Duarte, Gesine Paul · 2026 · Brain Behavior and Immunity
  72. Atherosclerotic Cardiovascular Diseases Increase ALS Risk by 82% While Optimal Cardiovascular Health Halves It: A 0.5‐Million Prospective Cohort Study
    Jiali Xie, Haobo Xie, Yaojia Li, Wenhua Jiang, Xinglin Wang, Qingjian Xie, Xueqin Song, Dongsheng Fan, Hong‐Fu Li, Binbin Deng · 2026 · Annals of Neurology
  73. Targeting the Immune-Neurovascular Interface to Ameliorate Pericyte Dysfunction with a Multifunctional Peptide–Drug Conjugate Nanoprodrug for Multiple Sclerosis Therapy
    Yongkang Mu, Kaichao Wen, Lingling Zhou, Zhiyong Gu, Tianying Wang, Yixian Li, Xiyu Yang, Xuan Liu, Xinyi Zhang, Wenya Chi et al. · 2026 · ACS Nano
  74. Multidimensional Spaceflight Stressors Disrupt Blood-Brain Barrier: A Comprehensive Review of Molecular Mechanisms
    YiTong GUO, Rong Liang, Jiajia Yang, Dong Ming · 2026 · Acta Astronautica
  75. Sonic hedgehog-matrix metalloproteinase crosstalk in neurovascular ageing and stroke: a potential mechanistic link
    Priya Bindal, Paul R. Kasher, Satoshi Ogawa · 2026 · GeroScience