Evaluation of androgen receptor transcriptional activities of bisphenol A, octylphenol and nonylphenol in vitro

Xu, Li-Chun; Sun, Hong; Chen, Jian-Feng; Bian, Qian; Qian, Jie; Song, Ling; Wang, Xin-Ru

doi:10.1016/j.tox.2005.08.006

Evaluation of androgen receptor transcriptional activities of bisphenol A, octylphenol and nonylphenol in vitro

In this study, we have developed a human androgen receptor (hAR) reporter gene assay using African monkey kidney cell line CV-1 transiently transfected with the constructed reporter gene plasmid pMMTV-CAT and the hAR expression plasmid AR/pcDNA3.1. The assay displayed appropriate response to the …