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Cited by 235Agricultural safety and regulationsFood Safety and HygieneHealthcare Regulation

The DOI matches its Crossref record; 4 of the 5 references it cites were found in a registry or an index.

Generally recognized as safe (GRAS): history and description

Burdock, George A, Carabin, Ioana G·2004·Toxicology Letters
DOI 10.1016/j.toxlet.2003.07.004
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Abstract

Generally recognized as safe (GRAS), a system for review and approval of ingredients for addition to food, was conceived at a time when the need for a less doctrinaire review of food ingredients was critical. The GRAS approval process for a food ingredient relies on the judgment of "...experts qualified by scientific training and experience to evaluate its safety..." the end product of which is no better or worse than that by FDA, but often more expeditious. The process and requirements for a successful GRAS determination are discussed and compared with that of the food additive petition (FAP) process. The future of the GRAS process is assured by its history of successful performance, bringing safe food ingredients to the consumer in a timely manner.

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Crossref · 10.1016/j.toxlet.2003.07.004

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Research works printed but not linked: 4

  1. Hutt, P.B., Merrill, R.A., 1991. Food and Drug Law, Cases and Materials, second ed. University Casebook Series, Foundation Press, Westbury, NY, 1354 pp.
  2. Hyman, P., 2002. US food and drug law and FDA—a historical background. In: Piña, K.R., Pines, W.L. (Eds.), A Practical Guide to Food and Drug Law Regulation, second ed. Food and Drug Law Institute, Washington, DC, pp. 15–45.
  3. Kotsonis, F., Burdock, G.A., Flamm, W.G., 2001. Food toxicology. In: Klaassen, C.D. (Ed), Toxicology: The Basic Science of Poisons, sixth ed. McGraw-Hill, New York, pp. 1049–1088 (Chapter 31).
  4. Kracov, D.A., 2002. The regulation of foods and food additives. In: Piña, K.R., Pines, W.L. (Eds.), A Practical Guide to Food and Drug Law Regulation, second ed. Food and Drug Law Institute, Washington, DC, pp. 159–214.

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Metadata

Authors
Burdock, G. A., & Carabin, I. G.
Corresponding author
Burdock, George A
ORCID
Burdock, George A
Venue
Toxicology Letters
Publisher
Elsevier BV
Published
2004-04
Volume
150
Issue
1
Pages
3-18
ISSN
0378-4274 (ISSN-L)
DOI
10.1016/j.toxlet.2003.07.004
OpenAlex
W2050665337
Cited by
235
References
5
Citations by year
2026: 25 · 2025: 22 · 2024: 26 · 2023: 21 · 2022: 27 · 2021: 16 · 2020: 11 · 2019: 14 · 2018: 14 · 2017: 7 · 2016: 11 · 2015: 4 · 2014: 8 · 2013: 8 · 2012: 3
FWCI
3.13
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Toxicology Letters (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural safety and regulations
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Food Safety and Hygiene
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Healthcare Regulation
Keywords
GRAS, food ingredient safety, FDA regulatory process, food additive regulation
MeSH terms
Food, Food Additives, Humans, Legislation, Food, United States, United States Food and Drug Administration, History, 20th Century

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