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Transfusion delay after hemoglobin trigger and in-hospital outcomes in patients with nonvariceal upper gastrointestinal bleeding

Lian, Xuhui, Zhang, Xu, He, Xianfang, Pan, Fuqiang·2026·Transfusion Clinique et Biologique
DOI 10.1016/j.tracli.2026.05.004
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Research works printed but not linked: 29

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  2. Sostres, 2011, Epidemiology and demographics of upper gastrointestinal bleeding: prevalence, incidence, and mortality, Gastrointest Endosc Clin N Am, 21, 567, 10.1016/j.giec.2011.07.004 · doi:10.1016/j.giec.2011.07.004
  3. Tinegate, 2013, Ten-year pattern of red blood cell use in the North of England, Transfusion, 53, 483, 10.1111/j.1537-2995.2012.03782.x · DOI
  4. Laine, 2012, Trends for incidence of hospitalization and death due to GI complications in the United States from 2001 to 2009, Am J Gastroenterol, 107, 1190, 10.1038/ajg.2012.168 · doi:10.1038/ajg.2012.168
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  6. Alali, 2023, Initial management of suspected acute upper gastrointestinal bleeding. Gastroenterol Rep (Oxf), 11
  7. Laine, 2021, ACG clinical guideline: upper gastrointestinal and ulcer bleeding, Am J Gastroenterol, 116, 899, 10.14309/ajg.0000000000001245 · DOI · Paper page
  8. Gralnek, 2021, Endoscopic diagnosis and management of nonvariceal upper gastrointestinal hemorrhage (NVUGIH): ESGE Guideline – update 2021, Endoscopy, 53, 300, 10.1055/a-1369-5274 · DOI · Paper page
  9. Barkun, 2019, Management of nonvariceal upper gastrointestinal bleeding: guideline recommendations from the International Consensus Group, Ann Intern Med, 171, 805, 10.7326/M19-1795 · DOI · Paper page
  10. Villanueva, 2013, Transfusion strategies for acute upper gastrointestinal bleeding, N Engl J Med, 368, 11, 10.1056/NEJMoa1211801 · DOI · Paper page
  11. Odutayo, 2017, Restrictive versus liberal blood transfusion for gastrointestinal bleeding: a systematic review and meta-analysis of randomised controlled trials, Lancet Gastroenterol Hepatol, 2, 354, 10.1016/S2468-1253(17)30054-7 · DOI · Paper page
  12. Wang, 2013, Restrictive vs. liberal transfusion for upper gastrointestinal bleeding: a meta-analysis of randomized controlled trials, World J Gastroenterol, 19, 6919, 10.3748/wjg.v19.i40.6919 · doi:10.3748/wjg.v19.i40.6919
  13. Chen, 2018, The association between red blood cell transfusion and outcomes in patients with upper gastrointestinal bleeding, Clin Transl Gastroenterol, 9, 138, 10.1038/s41424-018-0004-9 · doi:10.1038/s41424-018-0004-9
  14. Choi, 2025, Time to red blood cell transfusion and 30-day all-cause mortality in gastrointestinal bleeding: a nationwide cohort study, Ann Med, 57, 2474858, 10.1080/07853890.2025.2474858 · doi:10.1080/07853890.2025.2474858
  15. Marmo, 2025, Timing of red blood cell transfusion in upper gastrointestinal bleeding: does endoscopy timing and anemia severity matter?, Diseases, 13, 329, 10.3390/diseases13100329 · doi:10.3390/diseases13100329
  16. Mark, 2020, Predisposition to red blood cell transfusion in emergency department patients with acute upper gastrointestinal hemorrhage, Am J Emerg Med, 38, 746, 10.1016/j.ajem.2019.06.019 · DOI
  17. Jones, 2016, Immortal time bias in observational studies of time-to-event outcomes, J Crit Care, 36, 195, 10.1016/j.jcrc.2016.07.017 · DOI · Paper page
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  20. Kerbage, 2024, Blood transfusion management in upper gastrointestinal bleeding: does withholding or administering blood worsen outcomes?, Ann Gastroenterol, 37, 303
  21. Chapler, 1986, The physiologic reserve in oxygen carrying capacity: studies in experimental hemodilution, Can J Physiol Pharmacol, 64, 7, 10.1139/y86-002 · DOI
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  23. Villanueva, 2013, Transfusion strategies for acute upper gastrointestinal bleeding, N Engl J Med, 368, 11, 10.1056/NEJMoa1211801 · DOI · Paper page
  24. Choi, 2025, Association of time to red blood cell transfusion on outcomes in patients with gastrointestinal bleeding, Ann Med, 57, 2474858, 10.1080/07853890.2025.2474858 · doi:10.1080/07853890.2025.2474858
  25. Bilder, 2022, Impact of time to esophagogastroduodenoscopy in patients with nonvariceal upper gastrointestinal bleeding: a systematic review and meta-analysis, Rev Gastroenterol Mex (Engl Ed), 87, 320
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  28. Lau, 2020, Timing of endoscopy for acute upper gastrointestinal bleeding, N Engl J Med, 382, 1299, 10.1056/NEJMoa1912484 · doi:10.1056/nejmoa1912484
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Metadata

Authors
Lian, X., Zhang, X., He, X., & Pan, F.
Venue
Transfusion Clinique et Biologique
Publisher
Elsevier BV
Published
2026-08
Volume
33
Issue
3
Pages
158-164
ISSN
1246-7820
DOI
10.1016/j.tracli.2026.05.004
Cited by
0
References
1
Language
en
Licence

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CoChat. (2026). Citation check: Transfusion delay after hemoglobin trigger and in-hospital outcomes in patients with nonvariceal upper gastrointestinal bleeding. https://app.cochat.ai/papers/10.1016/j.tracli.2026.05.004
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Lian, X., Zhang, X., He, X., & Pan, F. (2026). Transfusion delay after hemoglobin trigger and in-hospital outcomes in patients with nonvariceal upper gastrointestinal bleeding. Transfusion Clinique et Biologique. https://doi.org/10.1016/j.tracli.2026.05.004

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.