First-in-human, double-blind, placebo-controlled, single-dose escalation study of aducanumab (BIIB037) in mild-to-moderate Alzheimer's disease
Ferrero, James, Williams, Leslie, Stella, Heather, Leitermann, Kate, Mikulskis, Alvydas, O'Gorman, John, Sevigny, Jeff·2016·Alzheimer's & Dementia: Translational Research & Clinical Interventions
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- Blood levels of glial fibrillary acidic protein for predicting clinical progression to Alzheimer’s disease in adults without dementia: a systematic review and meta-analysis protocolTakashi Nihashi, Keita Sakurai, Takashi Kato, Yasuyuki Kimura, Kengo Ito, Akinori Nakamura, Teruhiko Terasawa · 2024 · Diagnostic and Prognostic Research
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- Covalent fragment inhibits intramembrane proteolysisEden, Angela, Zhao, Jing, Xiao, Yuanyuan, Gibson, James, Wang, Chunyu · 2022 · Frontiers in Molecular Biosciences
- Neuropathological study of the effects of aducanumab anti-Aβ immunotherapy on patients with Alzheimer’s diseaseLindsay A. Welikovitch, Derek H. Oakley, Rachel E. Bennett, Alberto Serrano‐Pozo, Haoyang Zhu, Nancy E. Ruiz‐Uribe, Theodore J. Zwang, Lori Beth Chibnik, Teresa Gómez‐Isla, Matthew P. Frosch et al. · 2026 · Acta Neuropathologica
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- A novel GSK3β inhibitor ameliorates tau aggregation and neuroinflammation in Alzheimer's diseaseXinyue Ning, Wenjie Liu, Lijun Zhou, Nan Wang, Xinzhu Li, Limeng Wu, Zhenshu Li, Ai-Zhu Yang, Siyuan Liu, Zonghe Xu et al. · 2025 · Neurochemistry International
- Large-scale seroepidemiology uncovers nephro-urological pathologies in people with tau autoimmunityMagalhães, Andreia D., Emmenegger, Marc, De Cecco, Elena, Carta, Manfredi, Frontzek, Karl, Chincisan, Andra, Guo, Jingjing, Hornemann, Simone, Aguzzi, Adriano · 2025 · PLOS Biology
- Prediction of Monoclonal Antibodies Pharmacokinetics in Human: Identification of a Reference Neonatal Fc Receptor (FcRn) Binding Affinity Using Physiologically Based Pharmacokinetic (PBPK) ModelingSalih Benamara, Erik Sjögren, Florence Gattacceca, Marylore Chenel, Antoine Deslandes, Laurent Nguyen, Donato Teutonico · 2025 · ACS Pharmacology & Translational Science
- Near‐Infrared Aggregation‐Induced Emission Luminogens for In Vivo Theranostics of Alzheimer's DiseaseTianfu Zhang, Xiaoyu Chen, Congmin Yuan, Xiaobin Pang, Ping Shangguan, Yi‐Sheng Liu, Lulu Han, Jianwei Sun, Jacky W. Y. Lam, Yang Liu et al. · 2022 · Angewandte Chemie
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- N-terminal-targeted anti-amyloid monoclonal antibodies illuminate the therapy for Alzheimer’s disease: a systematic review and comprehensive meta-analysisYu-Hui Qiu, Ming Liu, Jie Zhan, Lingling Liu, Jiayi Zheng, Dan Wu, Guangliang Wu, Yefeng Cai, Shijie Zhang · 2023 · medRxiv
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