Inflammation as a central mechanism in Alzheimer's disease
Kinney, Jefferson W., Bemiller, Shane M., Murtishaw, Andrew S., Leisgang, Amanda M., Salazar, Arnold M., Lamb, Bruce T.·2018·Alzheimer's & Dementia: Translational Research & Clinical Interventions
Cited by (1,008)
Items 701–800 of 1,008
- Neuroprotective Potential and Underlying Pharmacological Mechanism of Carvacrol for Alzheimer’s and Parkinson’s DiseasesHayate Javed, Nagoor Meeran Mohamed Fizur, Niraj Kumar Jha, Ghulam Md Ashraf, Shreesh Kumar Ojha · 2022 · Current Neuropharmacology
- Shared Genes of PPARG and NOS2 in Alzheimer’s Disease and Ulcerative Colitis Drive Macrophages and Microglia Polarization: Evidence from Bioinformatics Analysis and Following ValidationLongcong Dong, Yuan Shen, Hongying Li, Ruibin Zhang, Shuguang Yu, Qiaofeng Wu · 2023 · International Journal of Molecular Sciences
- Peripheral Biomarkers in Manifest and Premanifest Huntington’s DiseaseEmanuele Morena, Carmela Romano, Martina Marconi, Selene Diamant, Maria Chiara Buscarinu, Gianmarco Bellucci, Silvia Romano, Daniela Scarabino, Marco Salvetti, Giovanni Ristori · 2023 · International Journal of Molecular Sciences
- Complexity of Sex Differences and Their Impact on Alzheimer’s DiseaseMarion Kadlecová, Kristine Freude, Henriette Haukedal · 2023 · Biomedicines
- Purpose in life and markers of immunity and inflammation: Testing pathways of episodic memoryA. Sutin, Y. Stephan, Martina Luchetti, A. Terracciano · 2023 · Journal of Psychosomatic Research
- Temporal trends and disparities of population attributable fractions of modifiable risk factors for dementia in China: a time-series study of the China health and retirement longitudinal study (2011–2018)Shanquan Chen, Xi Chen, Xiaohui Hou, Hai Fang, Gordon G. Liu, Lijing L. Yan · 2024 · The Lancet Regional Health - Western Pacific
- The role of exercise parameters on small extracellular vesicles and microRNAs cargo in preventing neurodegenerative diseasesFrancesco Fischetti, Luca Poli, Marina de Tommaso, Damiano Paolicelli, Gianpiero Greco, Stefania Cataldi · 2023 · Frontiers in Physiology
- The relationship between the gut microbiota and oxidative stress in the cognitive function of schizophrenia: A pilot study in ChinaHehua Li, Yuanyuan Huang, Liqin Liang, Hanqiu Li, Shijia Li, Yangdong Feng, Shixuan Feng, Kai Wu, Fengchun Wu · 2024 · Schizophrenia Research
- Polysaccharides extracted from common buckwheat (Fagopyrum esculentum) attenuate cognitive impairment via suppressing RAGE/p38/NF-κB signaling and dysbiosis in AlCl3-treated ratsYu-Chen Liu, Sheng-Yi Chen, Ying-Ying Chen, Hsin‐Yu Chang, I‐Chen Chiang, Gow‐Chin Yen · 2024 · International Journal of Biological Macromolecules
- Unveiling the role of astrogliosis in Alzheimer’s disease Pathology: Insights into mechanisms and therapeutic approachesMohit Paidlewar, Sneha Kumari, Rishika Dhapola, Prajjwal Sharma, Dibbanti HariKrishnaReddy · 2024 · International Immunopharmacology
- Advanced biomarkers: Beyond amyloid and tau: Emerging non-traditional biomarkers for alzheimer`s diagnosis and progressionMeher Rijwana Afrin, Pankaj Ghritakousik Upadhyaya, Abdul Hashim, Kunal Bhattacharya, Nongmaithem Randhoni Chanu, Dibyajyoti Das, Pukar Khanal, Satyendra Deka · 2025 · Ageing Research Reviews
- Uncovering plaque-glia niches in human Alzheimer’s disease brains using spatial transcriptomicsDenis R. Avey, Bernard Ng, Ricardo A. Vialle, Nicola A. Kearns, Kátia de Paiva Lopes, Artemis Iatrou, Sashini L De Tissera, Himanshu Vyas, Devin M. Saunders, Daniel J. Flood et al. · 2025 · Molecular Neurodegeneration Advances
- The Emerging Role of COX-2, 15-LOX and PPARγ in Metabolic Diseases and Cancer: An Introduction to Novel Multi-target Directed Ligands (MTDLs)Rana A. Alaaeddine, Perihan A. Elzahhar, Ibrahim AlZaim, Wassim G. Abou-Kheir, Ahmed S.F. Belal, Ahmed Fawzy EL‐Yazbi · 2020 · Current Medicinal Chemistry
- The clinical correlation of proinflammatory and anti-inflammatory biomarkers with Alzheimer disease: a meta-analysisUrati Anuradha, Anoop Kumar, Rakesh Kumar Singh · 2021 · Neurological Sciences
- GPCR19 Regulates P2X7R-Mediated NLRP3 Inflammasomal Activation of Microglia by Amyloid β in a Mouse Model of Alzheimer’s DiseaseJahirul Islam, Jung‐Ah Cho, Ju-yong Kim, Kyung Park, Young-Jae Koh, Chu Young Chung, Eun‐Jae Lee, Soo Jeong Nam, Kyoungyul Lee, Seoung-Heon Kim et al. · 2022 · Frontiers in Immunology
- Andrographolide exerts a neuroprotective effect by regulating the LRP1-mediated PPARγ/NF-κB pathwayYue Ju, Lili Gu, Min Shan Hu, Miao Zheng, Xuebin Zhou, Qin Li, Xinyue Zhang · 2023 · European Journal of Pharmacology
- The elusive role of herpesviruses in Alzheimer’s disease: current evidence and future directionsStacey L. Piotrowski, Allison Tucker, Steven Jacobson · 2023 · NeuroImmune Pharmacology and Therapeutics
- Differential roles of regulatory T cells in Alzheimer's diseaseAbdollah Jafarzadeh, Abdolkarim Sheikhi, Zahra Jafarzadeh, Maryam Nemati · 2023 · Cellular Immunology
- Comparison of the stability of glycoprotein acetyls and high sensitivity C ‐reactive protein as markers of chronic inflammationDaisy C P Crick, Golam Mohammed Khandaker, Sarah L. Halligan, David Paul Burgner, Toby Mansell, Abigail Fraser · 2023 · Immunology
- Latest advances in mechanisms of epileptic activity in Alzheimer’s disease and dementia with Lewy BodiesMariane Cristine Vicente, Kwaku Addo-Osafo, Keith A. Vossel · 2024 · Frontiers in Neurology
- Relationships between plasma biomarkers, tau PET, FDG PET, and volumetric MRI in mild to moderate Alzheimer's disease patientsDawn C. Matthews, Jefferson W. Kinney, Aaron R. Ritter, Randolph D. Andrews, Erin N. Toledano Strom, Ana S. Lukic, Lauren N. Koenig, Carolyn Revta, Howard M. Fillit, Kate Zhong et al. · 2024 · Alzheimer s & Dementia Translational Research & Clinical Interventions
- Cognitive Impairment in Patients with Ankylosing SpondylitisBruno Kusznir Vitturi, Enrico Stefano Suriano, Ana Beatriz Pereira de Souza, Dawton Yukito Torigoe · 2020 · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
- Multitarget Profiling of a Strigolactone Analogue for Early Events of Alzheimer’s Disease: In Vitro Therapeutic Activities against NeuroinflammationBegum Kurt, Adem Ozleyen, Gizem Antika, Yakup Berkay Yılmaz, Tugba Boyunegmez Tumer · 2020 · ACS Chemical Neuroscience
- Uncovering Plaque-Glia Niches in Human Alzheimer’s Disease Brains Using Spatial TranscriptomicsAvey, Denis R., Ng, Bernard, Vialle, Ricardo A., Kearns, Nicola A., de Paiva Lopes, Katia, Iatrou, Artemis, De Tissera, Sashini, Vyas, Himanshu, Saunders, Devin M., Flood, Daniel J. et al. · 2024
- Peripheral immune function and Alzheimer’s disease: a living systematic review and critical appraisalChihua Li, Rebecca C. Stebbins, Grace A. Noppert, Constanza X. Carney, Chunyu Liu, Ashley R. M. Sapp, Elijah J. Watson, Allison E. Aiello · 2023 · Molecular Psychiatry
- Emergence of the brain-border immune niches and their contribution to the development of neurodegenerative diseasesLi Yang Tan, Grace Cunliffe, Michael Patrick Hogan, Xin Yi Yeo, Chansik Oh, Bohwan Jin, Junmo Kang, Junho Park, Min‐Soo Kwon, MinYoung Kim et al. · 2024 · Frontiers in Immunology
- Inflammatory Manifestations Associated With Gut Dysbiosis in Alzheimer’s DiseaseSamat Kozhakhmetov, Aiym Kaiyrlykyzy, Zharkyn Jarmukhanov, E. B. Vinogradova, Gulnaz Zholdasbekova, Dinara Alzhanova, Jeannette Kunz, Almagul R. Kushugulova, Sholpan Askarova · 2024 · International Journal of Alzheimer s Disease
- Genetic and clinical correlates of two neuroanatomical AI dimensions in the Alzheimer’s disease continuumJunhao Wen, Zhijian Yang, Ilya M. Nasrallah, Yuhan Cui, Güray Erus, Dhivya Srinivasan, Ahmed Abdulkadir, Elizabeth Mamourian, Ioanna Skampardoni, Gyujoon Hwang et al. · 2024 · Translational Psychiatry
- Hampered AMPK-ULK1 cascade in Alzheimer’s disease (AD) instigates mitochondria dysfunctions and AD-related alterations which are alleviated by metforminArnaud Mary, Samantha Barale, Fanny Eysert, Audrey Valverde, Sandra Lacas‐Gervais, Charlotte Bauer, Sabiha Eddarkaoui, Luc Buée, Valérie Buée‐Scherrer, Frédéric Checler et al. · 2025 · Alzheimer s Research & Therapy
- Inherited risk of dementia and the progression of cerebral small vessel disease and inflammatory markers in cognitively healthy midlife adults: the PREVENT-Dementia studyAudrey Low, Li Su, James D. Stefaniak, Elijah Mak, Maria‐Eleni Dounavi, Graciela Muniz Terrera, Karen A. Ritchie, Craig William Ritchie, Hugh Stephen Markus, John Tiernan O'Brien · 2020 · Neurobiology of Aging
- Inflammatory cytokine levels implicated in Alzheimer’s disease moderate the effects of sex on verbal memory performanceJessica Caldwell, Jefferson W. Kinney, Aaron R. Ritter, Arnold Salazar, Christina G. Wong, Dietmar Cordes, George M. Slavich · 2020 · Brain Behavior and Immunity
- Recent trends in artificial intelligence-driven identification and development of anti-neurodegenerative therapeutic agentsKushagra Kashyap, Mohammad Imran Siddiqi · 2021 · Molecular Diversity
- Cannabinoid receptor 2 selective agonists and Alzheimer's disease: An insight into the therapeutic potentialsMagham Sai Varshini, Praveen Thaggikuppe Krishnamurthy, Neenu Shaji, Lalithkumar Mani, Shivaramakrishnan Balasubramanian · 2021 · Journal of Neuroscience Research
- Preventing Alzheimer's disease within reach by 2025: Targeted‐risk‐AD‐prevention (TRAP) strategyFrancesca Vitali, Gregory L. Branigan, Roberta Dı́az Brinton · 2021 · Alzheimer s & Dementia Translational Research & Clinical Interventions
- Comparison of Oleocanthal-Low EVOO and Oleocanthal against Amyloid-β and Related Pathology in a Mouse Model of Alzheimer’s DiseaseIhab M. Abdallah, Kamal M. Al-Shami, Amer E. Alkhalifa, Nour F. Al-Ghraiybah, Claudia Guillaume, Amal Kaddoumi · 2023 · Molecules
- Soluble and insoluble protein aggregates, endoplasmic reticulum stress, and vascular dysfunction in Alzheimer’s disease and cardiovascular diseasesEmily W. Waigi, Robert Clinton Webb, Melissa A. Moss, Mark J. Uline, Cameron Grant McCarthy, Camilla Ferreira Wenceslau · 2023 · GeroScience
- Is Drp1 a link between mitochondrial dysfunction and inflammation in Alzheimer’s disease?Oualid Sbai, Veronica Bazzani, Shreya Tapaswi, Joshua McHale, Carlo Vascotto, Lorena Perrone · 2023 · Frontiers in Molecular Neuroscience
- SLGCN: Structure-enhanced line graph convolutional network for predicting drug–disease associationsBao-Min Liu, Ying-Lian Gao, Feng Li, Chun-Hou Zheng, Jin‐Xing Liu · 2023 · Knowledge-Based Systems
- The shift in the fatty acid composition of the circulating lipidome in Alzheimer's diseaseFarida Dakterzada, Mariona Jové, José Luis Cantero, Natàlia Mota‐Martorell, Reinald Pamplona, Gerard Piñoll‐Ripoll · 2024 · Alzheimer s & Dementia
- Metabolic correlates of prevalent mild cognitive impairment and Alzheimer's disease in adults with Down syndromeMark E. Mapstone, Thomas J Gross, Fabio M. Macciardi, Amrita K. Cheema, Melissa E. Petersen, Elizabeth Head, Benjamin L. Handen, William Edward Klunk, Bradley T. Christian, Wayne P. Silverman et al. · 2020 · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
- Terpenoids of Ganoderma lucidum reverse cognitive impairment through attenuating neurodegeneration via suppression of PI3K/AKT/mTOR expression in vivo modelAnqi Wang, Changhao Xiao, Jianxian Zheng, Chuansong Ye, Zhen Dai, Qinghai Wu, Jinguang Liu, Pádraig Strappe, Zhongkai Zhou · 2020 · Journal of Functional Foods
- Mural Cells: Potential Therapeutic Targets to Bridge Cardiovascular Disease and NeurodegenerationAlexander Lin, Niridu Jude Peiris, Harkirat Dhaliwal, Maria Hakim, Weizhen Li, Subramaniam Ganesh, Yogambha Ramaswamy, Sanjay Patel, Ashish Misra · 2021 · Cells
- Nonlinear and vibrational microscopy for label-free characterization of amyloid-β plaques in Alzheimer's disease modelRenan Souza Cunha, Lucas Lafetá, Emerson Alberto Fonseca, Alexandre Simões Barbosa, Marco Aurélio Romano‐Silva, Rafael Pinto Vieira, Ado Jório, Leandro M. Malard · 2021 · The Analyst
- Evaluation of anti-Alzheimer activity of Echinacea purpurea extracts in aluminum chloride-induced neurotoxicity in rat modelMohamed, Salma M., Shalaby, Mostafa A., Al‑Mokaddem, Asmaa K., El-Banna, Ahmed H., EL-Banna, Hossny A., Nabil, Ghazal · 2023 · Journal of Chemical Neuroanatomy
- Control of the temporal development of Alzheimer’s disease pathology by the MR1/MAIT cell axisWyatt-Johnson, Season K., Kersey, Holly N., Codocedo, Juan F., Newell, Kathy L., Landreth, Gary E., Lamb, Bruce T., Oblak, Adrian L., Brutkiewicz, Randy R. · 2023 · Journal of Neuroinflammation
- Functional Role of Extracellular Vesicles in Skeletal Muscle Physiology and Sarcopenia: The Importance of Physical Exercise and NutritionMauro Lombardo, Gilda Aiello, Deborah Fratantonio, Sercan Karav, Sara Baldelli · 2024 · Nutrients
- Association Between the Gut Microbiota and Alzheimer’s Disease: An Update on Signaling Pathways and Translational TherapeuticsRutweek Kulkarni, Sneha Kumari, Rishika Dhapola, Prajjwal Sharma, Sunil Kumar Singh, Bikash Medhi, Dibbanti HariKrishnaReddy · 2024 · Molecular Neurobiology
- Inhibition of soluble epoxide hydrolase ameliorates cerebral blood flow autoregulation and cognition in alzheimer's disease and diabetes-related dementia rat modelsChengyun Tang, Jane J. Border, Huawei Zhang, Andrew Gregory, Shan Bai, Xing Fang, Yedan Liu, Shaoxun Wang, Sung Hee Hwang, Wen‐Jun Gao et al. · 2025 · GeroScience
- Gastrodin Ameliorates Tau Pathology and BBB Dysfunction in 3xTg‐AD Transgenic Mice by Regulating the ADRA1/NF‐κB/NLRP3 Pathway to Reduce NeuroinflammationBo Li, Li Wang, Yan Chun Xiao, Yang Wang, Yuanshang Wang, Yaqian Peng, Anni Zhang, Zhi Tang, Xiaolan Qi · 2025 · Phytotherapy Research
- Mitochondrial complex I deficiency induces Alzheimer's disease–like signatures that are reversible by targeted therapyHuanyao Gao, Kate N. Jensen, Jarred J. Nesbitt, Mark Ostroot, Gregory A. Cary, Jesse C. Wiley, Sergey Trushin, Jens O. Watzlawik, Wolfdieter Springer, Alexander S. Galkin et al. · 2025 · Alzheimer s & Dementia
- Neuroinflammation and Alzheimer's disease: Unravelling the molecular mechanismsAniket Kakkar, Harpreet Singh, Bhuvnesh Kumar Singh, Arvind Kumar, Arun Kumar Mishra, Hitesh Chopra · 2025 · Journal of Alzheimer s Disease
- Endoplasmic reticulum stress and unfolded protein response in immune cell functionGoshi Matsushima, Yuhki Yanase, Tadashi Nakagawa, Mitsuhiro Goda, Koichiro Ozawa, Toru Hosoi · 2025 · Frontiers in Immunology
- Expression of Cyp2c/Cyp2j subfamily members and oxylipin levels during LPS‐induced inflammation and resolution in miceJoan P. Graves, J. Alyce Bradbury, Artiom Gruzdev, Hong Li, Caroline Duval, Fred Bjørn Lih, Matthew L. Edin, Darryl C. Zeldin · 2019 · The FASEB Journal
- Cyclical amyloid beta-astrocyte activity induces oxidative stress in Alzheimer’s diseaseShalini Elangovan, R. M. Damian Holsinger · 2020 · Biochimie
- An Insight in Pathophysiological Mechanism of Alzheimer's Disease and its Management Using Plant Natural ProductsZeba Firdaus, Tryambak Deo Singh · 2020 · Mini-Reviews in Medicinal Chemistry
- Alterations of GABA B receptors in the APP/PS1 mouse model of Alzheimer's diseaseArnold Salazar, Amanda M. Leisgang Osse, Andrew Adonay Ortiz, Andrew S. Murtishaw, Jefferson W. Kinney · 2020 · Neurobiology of Aging
- An α-helix mimetic oligopyridylamide, ADH-31, modulates Aβ 42 monomer aggregation and destabilizes protofibril structures: insights from molecular dynamics simulationsAnupamjeet Kaur, Deepti Goyal, Bhupesh Goyal · 2020 · Physical Chemistry Chemical Physics
- Synergism and Subadditivity of Verbascoside-Lignans and -Iridoids Binary Mixtures Isolated from Castilleja tenuiflora Benth. on NF-κB/AP-1 Inhibition ActivityLuis David Arango-De la Pava, Alejandro Zamilpa, José Luis Trejo‐Espino, Blanca Eda Domínguez-Mendoza, Enrique Jiménez‐Ferrer, Leonor Pérez‐Martínez, Gabriela Trejo‐Tapia · 2021 · Molecules
- Nanotechnology as a therapeutic strategy to prevent neuropsychomotor alterations associated with hypercholesterolemiaMatheus Scarpatto Rodrigues, Gabriela Cristina de Paula, Mariane Bernardo Duarte, Victória Linden de Rezende, Jonathann Corrêa Possato, Hémelin Resende Farias, Eduarda Behenck Medeiros, Paulo Emílio Feuser, Emilio Luiz STRECK, Ricardo Andrez Machado‐de‐Ávila et al. · 2021 · Colloids and Surfaces B Biointerfaces
- Molecular subtyping of Alzheimer’s disease with consensus non-negative matrix factorizationChunlei Zheng, Rong Xu · 2021 · PLoS ONE
- Diabetes and inflammatory diseases: An overview from the perspective of Ca2+/3'-5'-cyclic adenosine monophosphate signalingLeandro Bueno Bergantin · 2021 · World Journal of Diabetes
- Dying by fire: noncanonical functions of autophagy proteins in neuroinflammation and neurodegenerationAlexis D. Rickman, Addison Hilyard, Bradlee L. Heckmann · 2021 · Neural Regeneration Research
- Combination Therapy in Alzheimer’s Disease: Is It Time?Arash Salehipour, Motahareh Bagheri, Mohammadmahdi Sabahi, Mahsa Dolatshahi, Delphine Boche · 2022 · Journal of Alzheimer s Disease
- Silk fibroin/cholinium gallate-based architectures as therapeutic toolsJoana M. Gomes, Simone S. Silva, Emanuel M. Fernandes, Flávia C. M. Lobo, Manuel Martín‐Pastor, Pablo Taboada, Rui Luís Reis · 2022 · Acta Biomaterialia
- Ginkgo Biloba Leaf Extract Improves an Innate Immune Response of Peripheral Blood Leukocytes of Alzheimer’s Disease PatientsMarta Sochocka, Michał Ochnik, Maciej Sobczyński, Katarzyna Gębura, Aleksandra Zambrowicz, Piotr Naporowski, Jerzy Leszek · 2022 · Nutrients
- Microglial Activation, Tau Pathology, and Neurodegeneration Biomarkers Predict Longitudinal Cognitive Decline in Alzheimer’s Disease ContinuumYi-He Chen, Rong-Rong Lin, Hui-Feng Huang, Yan‐Yan Xue, Qing‐Qing Tao · 2022 · Frontiers in Aging Neuroscience
- Changes in Plasma Neutral and Ether-Linked Lipids Are Associated with The Pathology and Progression of Alzheimer’s DiseaseFarida Dakterzada, Mariona Jové, Raquel P Huerto, Anna Carnes, Joaquím Sol, Reinald Pamplona, Gerard Piñol‐Ripoll · 2023 · Aging and Disease
- Early Life Obesity Increases Neuroinflammation, Amyloid Beta Deposition, and Cognitive Decline in a Mouse Model of Alzheimer’s DiseaseSimon W. So, Kendra M. Fleming, Joshua P. Nixon, Tammy A. Butterick · 2023 · Nutrients
- Cerebrospinal fluid inflammatory biomarkers for disease progression in Alzheimer’s disease and multiple sclerosis: a systematic reviewJoke Temmerman, Sebastiaan Engelborghs, Maria Bjerke, Miguel D’haeseleer · 2023 · Frontiers in Immunology
- Therapeutic considerations of bioactive compounds in Alzheimer's disease and Parkinson's disease: Dissecting the molecular pathwaysBanashree Chetia Phukan, Rubina Roy, Indira Gahatraj, Pallab Bhattacharya, Anupom Borah · 2023 · Phytotherapy Research
- Chronic neuroinflammation during aging leads to cholinergic neurodegeneration in the mouse medial septumRashmi Vasundhara Gamage, Ilaria Rossetti, Garry Niedermayer, Gerald W Münch, Yossi Buskila, Erika Gyengési · 2023 · Journal of Neuroinflammation
- P2X7 Receptor: an Emerging Target in Alzheimer’s DiseaseQiang Huang, Jun Ying, Wen Yu, Yao Dong, Hao Xiong, Yiping Zhang, Jie Liu, Xifeng Wang, Fuzhou Hua · 2023 · Molecular Neurobiology
- Risk of dementia in survivors of active tuberculosis in Korea: A nationwide cohort studyYohwan Yeo, Jung Eun Yoo, Kyungdo Han, Jin‐Hyung Jung, Hayoung Choi, Jongkyu Park, Dong Wook Shin, Hyun Jung Lee · 2023 · Journal of Infection and Public Health
- Switching On/Off Amyloid Plaque Formation in Transgenic Animal Models of Alzheimer’s DiseaseSergey A. Kozin, Olga I. Kechko, Alexei A. Adzhubei, Alexander А. Makarov, Vladimir A. Mitkevich · 2023 · International Journal of Molecular Sciences
- iPSC-derived PSEN2 (N141I) astrocytes and microglia exhibit a primed inflammatory phenotypeSullivan, Michael A., Lane, Samuel D., McKenzie, André D. J., Ball, Sarah R., Sunde, Margaret, Neely, G. Gregory, Moreno, Cesar L., Maximova, Alexandra, Werry, Eryn L., Kassiou, Michael · 2024 · Journal of Neuroinflammation
- Network pharmacology-based approach to elucidate the pharmacologic mechanisms of natural compounds from Dictyostelium discoideum for Alzheimer's disease treatmentNil Patil, Rupal Dhariwal, Arifullah Mohammed, Lee Seong Wei, Mukul Jain · 2024 · Heliyon
- Trajectory of brain-derived amyloid beta in Alzheimer’s disease: where is it coming from and where is it going?Ni Liu, Anaer Haziyihan, Wei Guang Zhao, Yu Chen, Hongbo Chao · 2024 · Translational Neurodegeneration
- The MARBLE Study Protocol: Modulating ApoE Signaling to Reduce Brain Inflammation, DeLirium, and PostopErative Cognitive DysfunctionKeith W. VanDusen, Sarada Eleswarpu, Eugene W. Moretti, Michael J. Devinney, Donna Crabtree, Daniel T. Laskowitz, Marty G. Woldorff, Kenneth Roberts, John Whittle, Jeffrey N. Browndyke et al. · 2020 · Journal of Alzheimer s Disease
- A microglia clonal inflammatory disorder in Alzheimer’s diseaseVicario, Rocio, Fragkogianni, Stamatina, Weber, Leslie, Lazarov, Tomi, Hu, Yang, Hayashi, Samantha Y, Craddock, Barbara, Socci, Nicholas D, Alberdi, Araitz, Baako, Ann et al. · 2025 · eLife
- Iron chelators: as therapeutic agents in diseasesZohreh Salimi, Mehdi Afsharinasab, Mehdi Rostami, Yaser Eshaghi Milasi, Seyedeh Fatemeh Musavi Ezmareh, Fariba Sakhaei, Maryam Mohammad-Sadeghipour, Sayyed Mehdi Rasooli Manesh, Zatollah Asemi · 2024 · Annals of Medicine and Surgery
- Beneficial versus Detrimental Effects of Complement–Microglial Interactions in Alzheimer’s DiseaseGunel Ayyubova, Nadeem Fazal · 2024 · Brain Sciences
- Edaravone Dexborneol ameliorates the cognitive deficits of APP/PS1 mice by inhibiting TLR4/MAPK signaling pathway via upregulating TREM2Jinyang Wang, Longyuan Du, Tianyun Zhang, Yun Chu, Yue Wang, Yu Tian Wang, Xiaoming Ji, Yunxiao Kang, Rui Cui, Guoliang Zhang et al. · 2024 · Neuropharmacology
- Extracellular vesicles in age-related diseases: disease pathogenesis, intervention, and biomarkerPuan Haliza Lintang Putri, Samira Husen Alamudi, Xuan Dong, Ying Long Fu · 2025 · Stem Cell Research & Therapy
- Nanoparticles for immunotherapyClément Anfray, Francesco Mainini, Fernando Torres Andón · 2020 · Frontiers of nanoscience
- Upregulation of Local Hepcidin Contributes to Iron Accumulation in Alzheimer’s Disease BrainsSuman Chaudhary, Ajay Ashok, Dallas McDonald, Aaron S. Wise, Alexander E. Kritikos, Neil A. Rana, Clifford V. Harding, Neena Singh · 2021 · Journal of Alzheimer s Disease
- Serum and cerebrospinal fluid Neutrophil gelatinase-associated lipocalin (NGAL) levels as biomarkers for the conversion from mild cognitive impairment to Alzheimer's disease dementiaPetrus J.W. Naudé, Inez H.G.B. Ramakers, Wiesje M. van der Flier, Lize Corrine Jiskoot, Fransje E. Reesink, Jurgen A.H.R. Claassen, Huiberdina L. Koek, Ulrich L.M. Eisel, Peter Paul De Deyn · 2021 · Neurobiology of Aging
- Long-Term Treatment of Cuban Policosanol Attenuates Abnormal Oxidative Stress and Inflammatory Response via Amyloid Plaques Reduction in 5xFAD MiceJinho Kim, Dong-Kyun Lim, Yoo‐Hun Suh, Keun‐A Chang · 2021 · Antioxidants
- Omarigliptin/galangin combination mitigates lipopolysaccharide-induced neuroinflammation in rats: Involvement of glucagon-like peptide-1, toll-like receptor-4, apoptosis and Akt/GSK-3β signalingAhmed M. Kabel, Hany H. Arab, Aliaa Atef, Remon S. Estfanous · 2022 · Life Sciences
- Mesenchymal Stem Cells Improve Cognitive Impairment and Reduce Aβ Deposition via Promoting AQP4 Polarity and Relieving Neuroinflammation in Rats With Chronic Hypertension-Induced Cerebral Small-Vessel DiseaseXiao lu Liu, Fubing Ouyang, Liu ting Hu, Pei Sun, Jing Yang, Yuan jing Sun, Mengshi Liao, Linfang Lan, Zhong Pei, Yu Fan · 2022 · Frontiers in Aging Neuroscience
- Synthesis and biological evaluation of thieno[3,2- c ]pyrazol-3-amine derivatives as potent glycogen synthase kinase 3β inhibitors for Alzheimer’s diseaseNing Yan, Xiaolong Shi, Long-Qian Tang, Defeng Wang, Xun Li, Chao Liu, Zhaopeng Liu · 2022 · Journal of Enzyme Inhibition and Medicinal Chemistry
- Early-life stress and dietary fatty acids impact the brain lipid/oxylipin profile into adulthood, basally and in response to LPSKitty Reemst, Jelle Y. Broos, Maralinde R. Abbink, Chiara Cimetti, Martin A. Giera, Gijs Kooij, Anikó Kőrösi · 2022 · Frontiers in Immunology
- The Impairment of Blood-Brain Barrier in Alzheimer’s Disease: Challenges and Opportunities with Stem CellsAdolfo López-Ornelas, Adriana Jiménez, Gilberto Pérez‐Sánchez, Citlali Ekaterina Rodríguez-Pérez, Alejandro Corzo‐Cruz, Iván Velasco, Enrique Estudillo · 2022 · International Journal of Molecular Sciences
- Targeting the liver in dementia and cognitive impairment: Dietary macronutrients and diabetic therapeuticsNicholas J. Hunt, Devin Wahl, Lara J. Westwood, Glen P. Lockwood, David George Le Couteur, Victoria Carroll Cogger · 2022 · Advanced Drug Delivery Reviews
- High resolution 16S rRNA gene Next Generation Sequencing study of brain areas associated with Alzheimer’s and Parkinson’s diseaseDavid C. Emery, Maria Davies, Tanya L. Cerajewska, Jelena Taylor, Mae Hazell, Alex R. Paterson, Shelley Jane Allen, Nicola Xania West · 2022 · Frontiers in Aging Neuroscience
- α7 nicotinic acetylcholine receptor in memory processingVerónica Estela Pastor, Jorge Horacio Medina · 2023 · European Journal of Neuroscience
- Serum levels of IL-6 are associated with cognitive impairment in the salus in apulia population-based studyChiara Griseta, Petronilla Battista, Fabio Castellana, Isabella Colonna, Sabrina Sciarra, Roberta Zupo, Ilaria Bortone, Luisa Lampignano, Sarah Tirelli, Giuseppe Berardino et al. · 2023 · Heliyon
- Hotspots and trends of microglia in Alzheimer's disease: a bibliometric analysis during 2000–2022Lijie Zhang, Qiuru Yao, Jinjing Hu, Baizhi Qiu, Yupeng Xiao, Qi Zhang, Yuting Zeng, Shuqi Zheng, Youao Zhang, Yantong Wan et al. · 2024 · European journal of medical research
- Neuroprotective potential of Erigeron bonariensis ethanolic extract against ovariectomized/D-galactose-induced memory impairments in female rats in relation to its metabolite fingerprint as revealed using UPLC/MSWeam W. Ibrahim, Rabab Hamed Sayed, Mohamed Fayed Abdelhameed, Enayat Abdel Aziz Omara, Mahmoud I. Nassar, Noha F. Abdelkader, Mohamed Ali Farag, Abdelsamed I. Elshamy, Sherif Mahmoud Afifi · 2024 · Inflammopharmacology
- Vaccines and Dementia: Part II. Efficacy of BCG and Other Vaccines Against DementiaCharles L. Greenblatt, Richard Lathe · 2024 · Journal of Alzheimer s Disease
- Research Progress on the Pathogenesis, Diagnosis, and Drug Therapy of Alzheimer’s DiseaseYixuan Yang, Lina Qiu · 2024 · Brain Sciences