The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
Chronic Prostatitis and/or Chronic Pelvic Pain as a Psychoneuromuscular Disorder—A Meta-analysis
Abstract
Objective To evaluate effectiveness of physical therapy, biofeedback, and/or cognitive behavioral therapy for chronic prostatitis/chronic pelvic pain syndrome (CP and/or CPPS). This symptom complex has resisted resolution from conventional urologic treatment of the prostate, which includes antibiotics, alpha-blockers, and analgesics. Beginning in 1995, a new paradigm was introduced viewing CP and/or CPPS as a psychoneuromuscular disorder driven by protective pelvic floor guarding and psychosocial stress.Methods A literature search (PubMed, Google Scholar, and the Cochran Library) was conducted from inception through December 2017 using key words related to CP and/or CPPS (eg, prostatitis and pelvic pain) with physical therapy (eg, myofascial trigger point release) and/or biofeedback or cognitive behavioral treatment. Studies were required to include pre- and post-treatment with the National Institutes of Health Chronic Prostatitis Symptom Index (CPSI) scores.Results Eight studies inclusive of 280 patients met primary inclusion criteria. Study sample sizes ranged from 8 to 116 men (mean = 35); treatment duration ranged from 8 to 26 weeks (mean = 14). Pretreatment mean CPSI scores ranged from 21.7 to 33.5. The nonstandardized weighted mean reduction of CPSI score from baseline was 8.8 points; 95% confidence interval (7.5, 11.1); P <.001. The I 2 statistic = 18.5% indicating little heterogeneity between studies. A sensitivity analysis including an additional multimodal intervention study of with 100 patients produced similar findings.Conclusion Conventional medical treatment often fails to resolve CP and/or CPPS. A 6-point reduction in CPSI score is considered a clinically meaningful improvement of symptoms. This meta-analysis shows that treating CP and/or CPPS as a psychoneuromuscular disorder can significantly exceed this clinical threshold.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Pelvic muscle relaxation and “reprogramming” the pelvic floor using physiotherapy techniques is effective for chronic pelvic pain.57”
From Psychological interventions for women with persistent pelvic pain: A survey of mental health clinicians (2021) · cites this paper as [57]
Citations
Cites
Wan, X., Wang, W., Liu, J., & Tong, T. (2014) · BMC Medical Research Methodology · doi:10.1186/1471-2288-14-135 · Cited by 11,735
NIH Consensus Definition and Classification of Prostatitis
Krieger, J. N., Leroy Nyberg, Jr., & Nickel, J. C. (1999) · JAMA · doi:10.1001/jama.282.3.236 · Cited by 1,464
Litwin, M. S., McNaughton‐Collins, M., Fowler, F. J., Nickel, J. C., Calhoun, E. A., Pontari, M. A., Alexander, R. B., Farrar, J. T., & O’Leary, M. P. (1999) · The Journal of Urology · doi:10.1016/s0022-5347(05)68562-x · Cited by 943
Krieger, J. N., Lee, S. W. H., Jeon, J., Cheah, P. Y., Liong, M. L., & Riley, D. E. (2008) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2007.08.028 · Cited by 389
Contemporary Management of Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Magistro, G., Wagenlehner, F. R. A., Grabe, M. J., Weidner, W., Stief, C. G., & Nickel, J. C. (2015) · European Urology · doi:10.1016/j.eururo.2015.08.061 · Cited by 294
FitzGerald, M. P., Anderson, R. U., Potts, J. M., Payne, C. K., Peters, K. M., Clemens, J. Q., Kotarinos, R. K., Fraser, L., Cosby, A., Fortman, C., et al. (2012) · The Journal of Urology · doi:10.1016/j.juro.2012.11.018 · Cited by 281
Self-citationManagement of Chronic Prostatitis/ Chronic Pelvic Pain Syndrome
Anothaisintawee, T. (2011) · JAMA · doi:10.1001/jama.2010.1913 · Cited by 277
Sickness Impact of Chronic Nonbacterial Prostatitis and its Correlates
Wenninger, K., Heiman, J. R., Rothman, I. K., Berghuis, J. P., & Berger, R. E. (1996) · The Journal of Urology · doi:10.1016/s0022-5347(01)66359-6 · Cited by 261
Schaeffer, A. J., KNAUSS, J. S., Landis, J. R., PROPERT, K. J., Alexander, R. B., Litwin, M. S., Nickel, J. C., O’Leary, M. P., Nadler, R. B., Pontari, M. A., et al. (2002) · The Journal of Urology · doi:10.1016/s0022-5347(05)64572-7 · Cited by 237
Anderson, R. U., Wise, D., SAWYER, T., & Chan, C. A. (2005) · The Journal of Urology · doi:10.1097/01.ju.0000161609.31185.d5 · Cited by 212
Self-citation
Cited by
Sorted by citations
Huang, X., Qin, Z., Cui, H., Chen, J., Liu, T., Zhu, Y., & Yuan, S. (2020) · Translational Andrology and Urology · doi:10.21037/tau.2020.01.25 · Cited by 50
A potential therapeutic strategy for prostatic disease by targeting the oral microbiome
Fang, C., Wu, L., Zhu, C., Xie, W., Hu, H., & Zeng, X. (2020) · Medicinal Research Reviews · doi:10.1002/med.21778 · Cited by 47
Cognitive behavioral therapy for the treatment of chronic pelvic pain
Urits, I., Callan, J., Moore, W., Fuller, M. C., Renschler, J. S., Fisher, P., Jung, J. W., Hasoon, J. J., Eskander, J. P., Kaye, A. D., et al. (2020) · Best practice & research. Clinical anaesthesiology · doi:10.1016/j.bpa.2020.08.001 · Cited by 50
Implications of the Genitourinary Microbiota in Prostatic Disease
Bajic, P., Dornbier, R. A., Doshi, C. P., Wolfe, A. J., Farooq, A. V., & Bresler, L. (2019) · Current Urology Reports · doi:10.1007/s11934-019-0904-6 · Cited by 38
Zhang, J., Zhang, X., Cai, Z., Ni, L., & Li, H. (2019) · American Journal of Men s Health · doi:10.1177/1557988319865380 · Cited by 38
Metadata
- Authors
- Anderson, R. U., Wise, D., & Nathanson, B. H.
- Affiliations
- Stanford Medicine (US)
- Corresponding author
- Anderson, Rodney U.
- Venue
- Urology
- Publisher
- Elsevier BV
- Published
- 2018-10
- Volume
- 120
- Pages
- 23-29
- ISSN
- 0090-4295 (ISSN-L)
- OpenAlex
- W2884475019
- Cited by
- 50
- References
- 32
- Citations by year
- 2026: 5 · 2025: 1 · 2024: 9 · 2023: 14 · 2022: 2 · 2021: 5 · 2020: 8 · 2019: 6
- FWCI
- 1.12
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Urology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Urology › Urinary Bladder and Prostate Research
- Health Sciences › Medicine › Urology › Pelvic floor disorders treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Keywords
- chronic prostatitis, physiotherapy, biofeedback, cognitive behavioral therapy, Chronic Prostatitis Symptom Index, psychosocial stress
- MeSH terms
- Biofeedback, Psychology, Chronic Disease, Exercise Therapy, Humans, Male, Pain Measurement, Prostatitis, Severity of Illness Index, Cognitive Behavioral Therapy, Treatment Outcome, Pelvic Pain, Chronic Pain, Pain Management
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
