The DOI matches its Crossref record.
Monitoring temperatures in the vaccine cold chain in Bolivia
Abstract
This study monitored vaccine cold chain temperatures during routine DTP-HB-Hib vaccine shipments from central stores to 11 communities in 3 provinces of Bolivia. In all 11 monitored shipments, vaccines were exposed to freezing temperatures at one or more points. In each of the shipments, temperatures below 0 degrees C were recorded for 2-50% of the monitoring period. Freezing occurred at almost every level of the cold chain distribution system, especially during district and health center storage and during transport to the province and district levels. Seven of the 11 shipments were exposed to temperatures above 8 degrees C, although none were exposed to excessive heat longer than 1.3% of the total monitoring period.
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In the citing paper
“As much as 37% of vaccines are exposed to temperatures below the recommended range in lower-income countries, making this a critical issue to address.7–13”
From Using Data to Keep Vaccines Cold in Kenya: Remote Temperature Monitoring With Data Review Teams for Vaccine Management (2019) · cites this paper as [9]
In the citing paper
“A number of studies have shown that exposure to temperature extremes within vaccine supply chains is relatively common in both developed and developing countries.”
From Using Data to Keep Vaccines Cold in Kenya: Remote Temperature Monitoring With Data Review Teams for Vaccine Management (2019) · cites this paper as [9]
Citations
Cites
No references could be resolved yet.
Research works printed but not linked: 9
- Nelson, 2004, Hepatitis B vaccine freezing in the Indonesian cold chain: evidence and solutions, Bull World Health Organ, 82, 99
- Hanjeet, 1996, Evaluation of cold chain monitoring in Kelantan, Malaysia, Bull World Health Organ, 74, 391
- Gold, 1999, Electronic temperature monitoring and feedback to correct adverse vaccine storage in general practice, Med J Aust, 19, 83, 10.5694/j.1326-5377.1999.tb123528.x · DOI
- Guthridge, 1996, Cold chain in a hot climate, Aust N Z J Pub Health, 20, 657, 10.1111/j.1467-842X.1996.tb01084.x · DOI
- Jeremijenko, 1996, Improving vaccine storage in general practice refrigerators, BMJ, 1651, 10.1136/bmj.312.7047.1651 · DOI
- Warwyk, 1997, Electronic monitoring of the vaccine cold chain in a metropolitan area: is the cold chain too cold?, BMJ, 315, 518, 10.1136/bmj.315.7107.518 · DOI
- Miller, 1994, Are childhood immunization programmes in Australia at risk? Investigation of the cold chain in the Northern Territory, Bull World Health Organ, 72, 401
- Diminsky, 1999, Physical, chemical, and immunological stability of CHO-derived hepatitis B surface antigen (HBsAg) particles, Vaccine, 18, 3, 10.1016/S0264-410X(99)00149-8 · DOI
- The effects of freezing on the appearance, potency, and toxicity of adsorbed and unadsorbed DTP vaccines. Wkly Epidemiol Rec 1980;55:385–92.
Cited by
Sorted by citations
Lutukai, M., Bunde, E. A., Hatch, B., Mohamed, Z., Yavari, S., Some, E., Chweya, A., Kania, C., Ross, J. C., Keddem, C., et al. (2019) · Global Health: Science and Practice · doi:10.9745/ghsp-d-19-00157 · Cited by 17
Metadata
- Authors
- Nelson, C., Froes, P., Dyck, A. M. V., Chavarría, J., Boda, E., Coca, A., Crespo, G., & Lima, H.
- Affiliations
- Program for Appropriate Technology in Health (US)
- United Nations Children's Fund (US)
- Ministerio de Salud (BO)
- Corresponding author
- Nelson, Carib
- ORCID
- Dyck, Anne Mie Van
- Venue
- Vaccine
- Publisher
- Elsevier BV
- Published
- 2007-01
- Volume
- 25
- Issue
- 3
- Pages
- 433-437
- ISSN
- 0264-410X (ISSN-L)
- OpenAlex
- W1998494449
- Cited by
- 60
- References
- 0
- Citations by year
- 2026: 1 · 2024: 1 · 2023: 3 · 2022: 2 · 2021: 7 · 2020: 3 · 2019: 6 · 2018: 2 · 2017: 7 · 2016: 5 · 2015: 1 · 2014: 7 · 2013: 3 · 2012: 2
- FWCI
- 2.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Vaccine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- UNICEF
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pharmaceutical Quality and Counterfeiting
- Life Sciences › Agricultural and Biological Sciences › Food Science › Food Supply Chain Traceability
- Health Sciences › Health Professions › Medical Laboratory Technology › Quality and Safety in Healthcare
- Keywords
- vaccine cold chain, vaccine temperature monitoring, vaccine storage, vaccine transport, freezing point, vaccine distribution, immunization programs, Bolivia
- MeSH terms
- Bolivia, Cold Temperature, Drug Storage, Freezing, Health Knowledge, Attitudes, Practice, Vaccines, Data Compression
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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Cite CoChat for the checks on this page, and the paper for its own findings.
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- CoChat. (2026). Citation check: Monitoring temperatures in the vaccine cold chain in Bolivia. https://app.cochat.ai/papers/10.1016/j.vaccine.2006.08.017
- The paper
- Nelson, C., Froes, P., Dyck, A. M. V., Chavarría, J., Boda, E., Coca, A., Crespo, G., & Lima, H. (2007). Monitoring temperatures in the vaccine cold chain in Bolivia. Vaccine. https://doi.org/10.1016/j.vaccine.2006.08.017
