Effectiveness of MF59-adjuvanted seasonal influenza vaccine in the elderly: A systematic review and meta-analysis

The Measurement of Observer Agreement for Categorical Data

Landis, J. R., & Koch, G. G. (1977) · Biometrics · doi:10.2307/2529310 · Cited by 81,148

Meta-analysis of Observational Studies in Epidemiology<SUBTITLE>A Proposal for Reporting</SUBTITLE>

Stroup, D. F. (2000) · JAMA · doi:10.1001/jama.283.15.2008 · Cited by 20,623

Untitled work

(2014) · Medical Entomology and Zoology · Cited by 17,633

Newcastle-Ottawa Scale: comparing reviewers’ to authors’ assessments

Lo, C. K.-L., Mertz, D., & Loeb, M. (2014) · BMC Medical Research Methodology · doi:10.1186/1471-2288-14-45 · Cited by 2,477

Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis

Osterholm, M. T., Kelley, N. S., Sommer, A., & Belongia, E. A. (2012) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(11)70295-x · Cited by 1,789

The Efficacy of Influenza Vaccine in Elderly Persons: A Meta-Analysis and Review of the Literature

Gross, P. A., Hermogenes, A. W., Sacks, H. S., Lau, J., & Levandowski, R. A. (1995) · Annals of Internal Medicine · doi:10.7326/0003-4819-123-7-199510010-00008 · Cited by 1,100

Vaccines against influenza WHO position paper – November 2012.

(2012) · PubMed · Cited by 782

Vaccines for preventing influenza in the elderly

Demicheli, V., Jefferson, T., Pietrantonj, C. D., Ferroni, E., Thorning, S., Thomas, R. E., & Rivetti, A. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004876.pub4 · Cited by 712

Efficacy and effectiveness of influenza vaccines in elderly people: a systematic review

Jefferson, T., Rivetti, D., Rivetti, A., Rudin, M., Di Pietrantonj, C., & Demicheli, V (2005) · The Lancet · doi:10.1016/s0140-6736(05)67339-4 · Cited by 601

Mortality benefits of influenza vaccination in elderly people: an ongoing controversy

Simonsen, L., Taylor, R. J., Viboud, C. G., Miller, M. A., & Jackson, L. A. (2007) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(07)70236-0 · Cited by 520

Improving pandemic preparedness through better, faster influenza vaccines

Newland, M., Durham, D. P., Asher, J., Treanor, J. J., Seals, J. R., Donis, R. O., & Johnson, R. A. (2021) · Expert Review of Vaccines · doi:10.1080/14760584.2021.1886931 · Cited by 17

Development of molecular clamp stabilized hemagglutinin vaccines for Influenza A viruses

McMillan, C. L. D., Cheung, S. T. M., Modhiran, N., Barnes, J., Amarilla, A. A., Bielefeldt‐Ohmann, H., Lee, L., Guilfoyle, K. A., van Amerongen, G., Stittelaar, K. J., et al. (2021) · npj Vaccines · doi:10.1038/s41541-021-00395-4 · Cited by 16

Safety and immunogenicity of the intranasal H3N2 M2-deficient single-replication influenza vaccine alone or coadministered with an inactivated influenza vaccine (Fluzone High-Dose Quadrivalent) in adults aged 65–85 years in the USA: a multicentre, randomised, double-blind, double-dummy, phase 1b trial

Eiden, J., Fierro, C. A., White, A., Davis, M., Rhee, M., Turner, M. A., Murray, B. J., Herber, R., Aitchison, R., Marshall, D. C., et al. (2024) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(24)00351-7 · Cited by 15

Influenza surveillance in Middle East, North, East and South Africa: Report of the 8th MENA Influenza Stakeholders Network

Abusrewil, S., Algeer, A., Aljifri, A. A., Slail, F. Y. A., Andrew, M. K., Eldin, M. A. T., Awaidy, S. T. A., Alaya, N. B. B., Khelil, J. B., Dbaibo, G. S., et al. (2019) · Influenza and Other Respiratory Viruses · doi:10.1111/irv.12628 · Cited by 14

Relative effectiveness of influenza vaccines in elderly persons in the United States, 2012/2013-2017/2018 seasons

Machado, M. A. D. Á., de Moura, C. S., Abrahamowicz, M., Ward, B. J., Pilote, L., & Bernatsky, S. (2021) · npj Vaccines · doi:10.1038/s41541-021-00373-w · Cited by 15

Multiplexed electrospray enables high throughput production of cGAMP microparticles to serve as an adjuvant for a broadly acting influenza vaccine

Batty, C. J., Gallovic, M. D., Williams, J. W., Ross, T. M., Bachelder, E. M., & Ainslie, K. M. (2022) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2022.121839 · Cited by 15

Association between vaccine adjuvant effect and pre-seasonal immunity. Systematic review and meta-analysis of randomised immunogenicity trials comparing squalene-adjuvanted and aqueous inactivated influenza vaccines

BEYER, W. E. P., Palache, A. M., Reperant, L. A., Boulfich, M., & Osterhaus, A. D. M. E. (2019) · Vaccine · doi:10.1016/j.vaccine.2019.12.037 · Cited by 15

Host immune response–inspired development of the influenza vaccine

Choi, A., García‐Sastre, A., & Schotsaert, M. (2020) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2020.04.008 · Cited by 15

Enhancing Immunogenicity of Influenza Vaccine in the Elderly through Intradermal Vaccination: A Literature Analysis

Quach, H. Q., & Kennedy, R. B. (2022) · Viruses · doi:10.3390/v14112438 · Cited by 15

Polyfunctional antibodies: a path towards precision vaccines for vulnerable populations

Purcell, R. A., Theisen, R. M., Arnold, K. B., Chung, A. W., & Selva, K. J. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1183727 · Cited by 16

A Cohort Study on Influenza Vaccine and All-Cause Mortality in Older Adults: Methodological Concerns and Public Health Implications

Lapi, F., Marconi, E., Gualano, M. R., Vetrano, D. L., Grattagliano, I., Rossi, A., & Cricelli, C. A. (2022) · Drugs & Aging · doi:10.1007/s40266-022-00958-7 · Cited by 14

Zusammensetzung und Wirkmechanismen von Adjuvanzien in zugelassenen viralen Impfstoffen

Wagner, R., & Hildt, E. (2019) · Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz · doi:10.1007/s00103-019-02921-1 · Cited by 14

Vaccination of aged mice with adjuvanted recombinant influenza nucleoprotein enhances protective immunity

Cookenham, T. S., Lanzer, K. G., Gage, E., Lorenzo, E. C., Carter, D., Coler, R. N., Baldwin, S. L., Haynes, L., Reiley, W. W., & Blackman, M. A. (2020) · Vaccine · doi:10.1016/j.vaccine.2020.05.085 · Cited by 14

Influenza: overview on prevention and therapy

Robson, C., Baskar, S. R., Booy, R., Ferguson, P. E., Gilroy, N. M., Kok, J., Sandaradura, I., & Dwyer, D. E. (2019) · Australian Prescriber · doi:10.18773/austprescr.2019.013 · Cited by 13

Immunogenicity and safety of the MF59-adjuvanted seasonal influenza vaccine in non-elderly adults: A systematic review and meta-analysis

Domnich, A., Trombetta, C.-S., Fallani, E., & Salvatore, M. (2024) · PLoS ONE · doi:10.1371/journal.pone.0310677 · Cited by 16

The older traveller

Woś, M., & Korzeniewski, K. (2018) · International Maritime Health · doi:10.5603/imh.2018.0045 · Cited by 14

Cost-effectiveness of high dose versus adjuvanted trivalent influenza vaccines in England and Wales

Mattock, R., Gibbons, I., Moss, J. W. E., Mealing, S., Largeron, N., Carroll, S., & Alvarez, F. P. (2021) · Journal of Medical Economics · doi:10.1080/13696998.2021.2000780 · Cited by 12

Tailoring vaccines for older people and the very young

Keener, A. B. (2019) · Nature · doi:10.1038/d41586-019-03638-6 · Cited by 12

Effectiveness of influenza vaccine in reducing influenza-associated hospitalizations and deaths among the elderly population; Lazio region, Italy, season 2016-2017

Fabiani, M., Volpe, E., Faraone, M., Bella, A., Pezzotti, P., & Chini, F. (2020) · Expert Review of Vaccines · doi:10.1080/14760584.2020.1750380 · Cited by 12

T Cell Transcriptional Signatures of Influenza A/H3N2 Antibody Response to High Dose Influenza and Adjuvanted Influenza Vaccine in Older Adults

Haralambieva, I. H., Quach, H. Q., Ovsyannikova, I. G., Goergen, K. M., Grill, D. E., Poland, G. A., & Kennedy, R. B. (2022) · Viruses · doi:10.3390/v14122763 · Cited by 10

Longevity of protective immune responses induced by a split influenza A (H7N9) vaccine mixed with MF59 adjuvant in BALB/c mice

Ou, H., Yao, W. Q., Yu, D.-S., Weng, T.-H., Wang, F. X. C., Wu, X., Wu, H., Cheng, L., Lu, X., Wu, N., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.20064 · Cited by 11

Enhanced Passive Safety Surveillance (EPSS) confirms an optimal safety profile of the use of MF59®‐adjuvanted influenza vaccine in older adults: Results from three consecutive seasons

Panatto, D., Haag, M. D. M., Lai, P. L., Tomczyk, S., Amicizia, D., & Lino, M. M. (2019) · Influenza and Other Respiratory Viruses · doi:10.1111/irv.12685 · Cited by 10

Achieving Influenza Vaccine Uptake Target in Canada via a Pharmacy-Led Telephone Discussion during the 2019–2020 Season

Strain, W. D., Mansi, J. A., Boikos, C., Boivin, M., & Fisher, W. A. (2021) · Vaccines · doi:10.3390/vaccines9040312 · Cited by 11

Effective Immunization of Older Adults Against Seasonal Influenza

Schaffner, W., Chen, W. H., HOPKINS, R. H., & Neuzil, K. M. (2018) · The American Journal of Medicine · doi:10.1016/j.amjmed.2018.02.019 · Cited by 13

Relapse of polymyalgia rheumatica following adjuvanted influenza vaccine: A case-based review

Bassendine, M. F., & Bridge, S. H. (2020) · European Journal of Rheumatology · doi:10.5152/eurjrheum.2019.19152 · Cited by 12

Vaccines We Need But Don't Have

Plotkin, S. A. (2017) · Viral Immunology · doi:10.1089/vim.2017.0126 · Cited by 10

Adjuvanted versus non-adjuvanted standard-dose influenza vaccines in preventing all-cause hospitalizations in the elderly: a cohort study with nested case-control analyses over 18 influenza seasons

Lapi, F., Domnich, A., Marconi, E., Rossi, A., & Cricelli, C. A. (2022) · Expert Review of Vaccines · doi:10.1080/14760584.2022.2115362 · Cited by 13

Vaccine-Preventable Diseases in Older Adults

Al-Jabri, M., Rosero, C., & Saade, E. (2023) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2025.09.009 · Cited by 10

Humoral Response to the Acetalated Dextran M2e Vaccine is Enhanced by Antigen Surface Conjugation

Batty, C. J., Pena, E. S., Amouzougan, E. A., Moore, K. M., Ainslie, K. M., & Bachelder, E. M. (2023) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.3c00223 · Cited by 10

Novel Influenza Vaccines: From Research and Development (R&D) Challenges to Regulatory Responses

He, X., Zhang, T., Huan, S., & Yue, Y. (2023) · Vaccines · doi:10.3390/vaccines11101573 · Cited by 10

Importance of adjuvant selection in tuberculosis vaccine development: Exploring basic mechanisms and clinical implications

Choi, H., Kwon, K. W., & Shin, S. J. (2023) · Vaccine X · doi:10.1016/j.jvacx.2023.100400 · Cited by 12

An exploratory study to assess patterns of influenza- and pneumonia-related mortality among the Italian elderly

Fallani, E., Orsi, A., Signori, A., Icardi, G., & Domnich, A. (2021) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2021.2005381 · Cited by 9

Risk for Shoulder Conditions After Vaccination: A Population-Based Study Using Real-World Data

Zheng, C., Duffy, J., Liu, I. A., Sy, L. S., Chen, W., Qian, L., Navarro, R. A., Ryan, D. S., Kim, S. S., Mercado, C., et al. (2022) · Annals of Internal Medicine · doi:10.7326/m21-3023 · Cited by 11

Hemagglutinin virus-like particles incorporated with membrane-bound cytokine adjuvants provide protection against homologous and heterologous influenza virus challenge in aged mice

Park, B. R., Bommireddy, R., Chung, D. H., Kim, K., Subbiah, J., Jung, Y., Bhatnagar, N., Pack, C. D., Ramachandiran, S., Reddy, S. J. C., et al. (2023) · Immunity & Ageing · doi:10.1186/s12979-023-00344-w · Cited by 9

Revisiting the dimensions of universal vaccine with special focus on COVID-19: Efficacy versus methods of designing

Jaishwal, P., Jha, K., & Singh, S. P. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.134012 · Cited by 10

Use of adjuvanted trivalent influenza vaccine in older-age adults: a systematic review of economic evidence

Loperto, I., Simonetti, A., Nardone, A., & Triassi, M. (2019) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2019.1578597 · Cited by 9

Preventing the Risk of Hospitalization for Respiratory Complications of Influenza among the Elderly: Is There a Better Influenza Vaccination Strategy? A Retrospective Population Study

Cocchio, S., Gallo, T., Zotto, S. D., Clagnan, E., Iob, A., Furlan, P., Fonzo, M., Bertoncello, C., & Baldo, V. (2020) · Vaccines · doi:10.3390/vaccines8030344 · Cited by 9

Next Generation Influenza Vaccines: Looking into the Crystal Ball

Guzmán, C. A. (2020) · Vaccines · doi:10.3390/vaccines8030464 · Cited by 10

Development of vaccines at the time of COVID-19

Almond, J., Hacker, J. H., Harwood, C. R., Pizza, M., Rappuoli, R., Ron, E. Z., Sansonetti, P. J., Vanderslott, S., & Wieler, L. H. (2020) · microLife · doi:10.1093/femsml/uqaa003 · Cited by 9

Self-reported diabetes and herpes zoster are associated with a weak humoral response to the seasonal influenza A H1N1 vaccine antigen among the elderly

Akmatov, M. K., Riese, P., Trittel, S., May, M., Prokein, J., Illig, T., Schindler, C., Guzmán, C. A., & Peßler, F. (2019) · BMC Infectious Diseases · doi:10.1186/s12879-019-4214-x · Cited by 8

Influenza Vaccine Effectiveness Against Symptomatic Influenza in Primary Care: A Test Negative Case Control Study Over Two Influenza Seasons 2022/2023 and 2023/2024 in Ireland

Marron, L., McKenna, A., O’Donnell, J., Joyce, M., Bennett, C., Connell, J., & Domegan, L. M. (2024) · Influenza and Other Respiratory Viruses · doi:10.1111/irv.70023 · Cited by 8

Influenza vaccination of home health care staff and the impact on patient hospitalizations

Shang, J., Harrison, J. M., Chastain, A. M., Stone, P. W., Perera, U. G. E., Madigan, E. A., Pogorzelska‐Maziarz, M., & Dick, A. W. (2022) · American Journal of Infection Control · doi:10.1016/j.ajic.2021.12.027 · Cited by 8

The safety and immunogenicity of vaccines administered to pregnant women living with HIV: a systematic review and meta-analysis

Nakabembe, E., Cooper, J., Amaral, K., Tusubira, V., Hsia, Y., Abu-Raya, B., Sekikubo, M., Nakimuli, A., Sadarangani, M., & Doaré, K. L. (2024) · EClinicalMedicine · doi:10.1016/j.eclinm.2024.102448 · Cited by 8

Effectiveness of influenza vaccine among the population in Chongqing, China, 2018–2022: A test negative design-based evaluation

Yang, S., Wáng, Q., Li, T., Long, J., Xiong, Y., Feng, L., Wáng, Q., Zhao, Y., Yang, J., Tang, W., et al. (2024) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2024.2376821 · Cited by 7

Analysis of R848 as an Adjuvant to Improve Inactivated Influenza Vaccine Immunogenicity in Elderly Nonhuman Primates

Crofts, K. F., Holbrook, B. C., D’Agostino, R. B., & Alexander‐Miller, M. A. (2022) · Vaccines · doi:10.3390/vaccines10040494 · Cited by 8

Innovative translational platforms for rapid developing clinical vaccines against COVID‐19 and other infectious disease

Wang, N., & Wang, T. (2024) · Biotechnology Journal · doi:10.1002/biot.202300658 · Cited by 11

Recent developments of vaccines for older adults: Adjuvants and beyond

Pangrazzi, L., & Weinberger, B. (2025) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2025.2517931 · Cited by 9

Harnessing T Follicular Helper Cell Responses for HIV Vaccine Development

Niessl, J., & Kaufmann, D. (2018) · Viruses · doi:10.3390/v10060336 · Cited by 8

Endoplasmic reticulum stress response and bile acid signatures associate with multi-strain seroresponsiveness during elderly influenza vaccination

Carré, C., Wong, G. C. L., Narang, V., Tan, C. T., Chong, J., Chin, H. X., Xu, W., Lu, Y., Chua, M., Poidinger, M., et al. (2021) · iScience · doi:10.1016/j.isci.2021.102970 · Cited by 7

Relative effectiveness of adjuvanted versus non-adjuvanted influenza vaccines in older adults with risk factors for influenza complications during the 2019–2020 U.S. influenza season

Imran, M., Mills, C., McDermott, K. W., Dean, A., Bogdanov, A., McGovern, I., & Haag, M. D. M. (2024) · Vaccine · doi:10.1016/j.vaccine.2024.126316 · Cited by 6

Evaluating risk of bias using ROBINS-I tool in nonrandomized studies of adjuvanted influenza vaccine

Grabenstein, J. D., Ferrara, P., Mantovani, L. G., & McGovern, I. (2023) · Vaccine · doi:10.1016/j.vaccine.2023.11.005 · Cited by 6

Serologic response to sequential vaccination with enhanced influenza vaccines: Open label randomized trial among adults aged 65–74 years

McLean, H. Q., Levine, M. Z., King, J. P., Flannery, B. L., & Belongia, E. A. (2021) · Vaccine · doi:10.1016/j.vaccine.2021.10.072 · Cited by 5

Enhanced passive safety surveillance of the MF59-adjuvanted quadrivalent influenza vaccine in the elderly during the 2021/22 influenza season

Amicizia, D., Domnich, A., Lai, P. L., Orsi, A., Icardi, G., Tkach-Motulyak, O., & Panatto, D. (2023) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2023.2190279 · Cited by 6

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Kennedy, R. B., Ovsyannikova, I. G., & Poland, G. A. (2021) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2021.08.003 · Cited by 6

Mood and influenza vaccination in older adults: A randomized controlled trial.

Ayling, K., Fairclough, L. C., Buchanan, H., Wetherell, M. A., & Vedhara, K. (2019) · Health Psychology · doi:10.1037/hea0000786 · Cited by 5

Poly-γ-glutamic acid/Alum adjuvanted pH1N1 vaccine-immunized aged mice exhibit a significant increase in vaccine efficacy with a decrease in age-associated CD8+ T cell proportion in splenocytes

Yang, J., Kim, J., Kwak, C., & Poo, H. (2022) · Immunity & Ageing · doi:10.1186/s12979-022-00282-z · Cited by 5

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Mohn, K. G.-I., & Zhou, F. (2018) · Vaccines · doi:10.3390/vaccines6020032 · Cited by 5

Optical Density Value and Ratio as Novel Indexes for Nanoemulsion Sterile Filtration Process Control or Characterization

Wang, Z., Shan, P., Wei, D., Hao, S., Zhang, Z., Li, S., & Xu, J. (2020) · Journal of Pharmaceutical Sciences · doi:10.1016/j.xphs.2020.12.032 · Cited by 5

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Kline, A., Trinh, L. N., Hussein, M. H., Elshazli, R. M., Toraih, E. A., Duchesne, J. C., Fawzy, M. S., & Kandil, E. H. (2021) · International Journal of Clinical Practice · doi:10.1111/ijcp.14901 · Cited by 5

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Law, N., & Kumar, D. (2017) · Drugs & Aging · doi:10.1007/s40266-017-0491-5 · Cited by 5

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Jung, M., Kim, H., Choi, E., Shin, M., & Shin, S. J. (2024) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2024.2317439 · Cited by 5

Adjuvanted-influenza vaccination in patients infected with HIV: a systematic review and meta-analysis of immunogenicity and safety

Chen, Y., Zhou, J., Tian, J., Li, B.-H., Liu, L., & Wei, K. (2019) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2019.1672492 · Cited by 4

Journal of Preventive Medicine and Hygiene, Vol. 63 No. 4S1 (2022): L’Health Technology Assessment come strumento value-based per la valutazione delle tecnologie sanitarie. Reassessment del vaccino antinfluenzale quadrivalente da coltura cellulare: Flucelvax Tetra® 2.0

Hygiene, J. O. P. M. A. (2023) · PubMed Central · doi:10.15167/2421-4248/jpmh2022.63.4s1 · Cited by 4

Risikoimpfungen im Alter

Forstner, C., Kwetkat, A., Schleenvoigt, B. T., & Pletz, M. W. (2018) · MMW - Fortschritte der Medizin · doi:10.1007/s15006-018-0029-8 · Cited by 4

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BEYER, W. E. P., Palache, A. M., Boulfich, M., & Osterhaus, A. D. M. E. (2022) · Vaccine · doi:10.1016/j.vaccine.2022.04.049 · Cited by 4

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Pebody, R. G., Zambon, M. C. F. A., & Ramsay, M. E. (2018) · BMJ · doi:10.1136/bmj.k2705 · Cited by 4

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de Lejarazu, R. O., Díez‐Domingo, J., de Miguel, Á. G., Martinón‐Torres, F., Margüello, E. R., Claver, J. L. L.-B., Palomo-Jimenez, P. I., Avellà, J. M. F., & Perpiñán, J. M. A. (2025) · BMC Infectious Diseases · doi:10.1186/s12879-025-10442-3 · Cited by 5

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Shi, J., Hong, L., Zhang, Y., Ye, C., Huang, X., Lu, Y., Liu, Y., Liu, J., Ao, D., Zhou, Y., et al. (2025) · MedComm · doi:10.1002/mco2.70301 · Cited by 3

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Hannaford, A., Aleissa, M. M., & Sherman, A. C. (2025) · The American Journal of the Medical Sciences · doi:10.1016/j.amjms.2025.10.010 · Cited by 4

Optimizing sterile filtration of nanoemulsions through proper choice of prefilter properties

Kapila, S., Soukup, R. J., Bradley, M. E., Boyd, D., & Zydney, A. L. (2025) · Biotechnology Progress · doi:10.1002/btpr.70087 · Cited by 3

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Milicic, A., Reinke, S., Fergusson, J. R., Lindblad, E. B., Thakur, A., Corby, G., Longet, S., Górska, S., Razim, A., Hu, K., et al. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91146-7.00009-3 · Cited by 4

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Martins, A. M., Juan, L. F. V., Santos, M., & Martins, J. P. (2025) · Vaccines · doi:10.3390/vaccines13080859 · Cited by 3

Comparative analysis of cellular immune responses to four seasonal inactivated influenza vaccines in younger and older adults

Silva‐Moraes, V., Reis, L. R., & Ross, T. M. (2025) · The Journal of Immunology · doi:10.1093/jimmun/vkaf286 · Cited by 3

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Mara, K., Dai, M., Brice, A. M., Alexander, M. R., Tribolet, L., Layton, D., & Bean, A. G. D. (2021) · Vaccines · doi:10.3390/vaccines9010059 · Cited by 3

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Gorse, G. J., Grimes, S., Buck, H., Mulla, H., White, P. T., Hill, H., May, J. M., Frey, S. E., & Blackburn, P. (2022) · Vaccine · doi:10.1016/j.vaccine.2022.01.035 · Cited by 3

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Doyon-Plourde, P., Fortin, É., & Quach, C. (2022) · Vaccine · doi:10.1016/j.vaccine.2022.08.012 · Cited by 3

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Kwetkat, A., Heppner, H. J., Endres, A., & Leischker, A. H. (2021) · Der Internist · doi:10.1007/s00108-021-01101-1 · Cited by 3

Characteristics and methodological standards across systematic reviews with Meta-analysis of efficacy and/or effectiveness of influenza vaccines: an overview of reviews

Okoli, G. N., Reddy, V. K., Lam, O., Racovitan, F., Al‐Yousif, Y., & Askin, N. (2022) · Scandinavian Journal of Infectious Diseases · doi:10.1080/23744235.2022.2114537 · Cited by 2

Population-Based Analysis of Vaccination Status and Post-Vaccination Adverse Events in Adults Aged 55 and Older

Frydrysiak-Brzozowska, A., Haor, B., Pluta, A., & Głowacka, M. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14124297 · Cited by 2

Roads to advanced vaccines: influenza case study

Riese, P., & Guzmán, C. A. (2017) · Microbial Biotechnology · doi:10.1111/1751-7915.12835 · Cited by 2

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Yu, R., Guo, Y., Zhang, S., Ai, Y., Wei, R., Li, Y., Chen, H., Liu, S., Zhang, C., Yao, Y., et al. (2025) · Vaccines · doi:10.3390/vaccines13111162 · Cited by 1

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Zhang, P., Yang, X., & Chen, B. (2026) · Vaccines · doi:10.3390/vaccines14030243 · Cited by 1

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Nguyen, T. H. O., Foo, I. J. H., Purcell, R. A., Tan, H., Deliyannis, G., Zhang, W., Carolan, L. A., Hadiprodjo, A. J., Huang, H. H., Allen, L. F., et al. (2026) · Science Translational Medicine · doi:10.1126/scitranslmed.aea8621 · Cited by 1

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Tian, J., Fu, W., Xie, Z., Wang, X., Miao, M., Shan, F., & Yu, X. (2023) · BMC Immunology · doi:10.1186/s12865-023-00573-0 · Cited by 1

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Kwetkat, A., Endres, A., Leischker, A. H., & Heppner, H. J. (2020) · DMW - Deutsche Medizinische Wochenschrift · doi:10.1055/a-1073-3171 · Cited by 1

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Minozzi, S., Lytras, T., Gianola, S., González‐Lorenzo, M., Castellini, G., Galli, C., Cereda, D., Bonovas, S., & Pariani, E. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3895644 · Cited by 1

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Quaile, A. (2018) · Nurse Prescribing · doi:10.12968/npre.2018.16.1.10

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Seybold, U. (2018) · e Curriculum Innere Medizin · doi:10.1007/s40531-018-0021-y

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Valiquette, L., & Laupland, K. B. (2018) · Journal of the Association of Medical Microbiology and Infectious Disease Canada · doi:10.3138/jammi.2018.02.14

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Nguyen‐Van‐Tam, J. S. (1996) · Biomedicine & Pharmacotherapy · doi:10.1016/0753-3322(96)85298-x

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Buynder, P. G. V., Konrad, S., Buynder, J. L. V., Brodkin, E., Krajden, M., Ramler, G., & Bigham, M. (2013) · Vaccine · doi:10.1016/j.vaccine.2013.07.059 · Cited by 159

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Lapi, F., Marconi, E., Simonetti, M., Baldo, V., Rossi, A., Sessa, A., & Cricelli, C. A. (2019) · Expert Review of Vaccines · doi:10.1080/14760584.2019.1622418 · Cited by 47

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Martínez, M., Bouza, J., Rubió, P. P., Puig-Barberà, J., Aragón, J., & Lana, Á. T. (2023) · Revista Espanola de Quimioterapia · doi:10.37201/req/145.2022 · Cited by 6

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