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The role of polyomaviruses in human disease

Open access
Jiang, Mengxi, Abend, Johanna R., Johnson, Silas F., Imperiale, Michael J.·2009·Virology

Abstract

The human polyomaviruses, BK virus and JC virus, have long been associated with serious diseases including polyomavirus nephropathy and progressive multifocal leukoencephalopathy. Both viruses establish ubiquitous, persistent infections in healthy individuals. Reactivation can occur when the immune system is impaired, leading to disease progression. Recently, the human polyomavirus family has expanded with the identification of three new viruses (KI, WU and Merkel cell polyomavirus), all of which may prove to be involved in human disease. This review describes the general aspects of human polyomavirus infections and pathogenicity. Current topics of investigation and future directions in the field are also discussed.

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Crossref · 10.1016/j.virol.2008.09.027

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Metadata

Authors
Jiang, M., Abend, J. R., Johnson, S. F., & Imperiale, M. J.
Venue
Virology
Publisher
Elsevier BV
Published
2009-02
Volume
384
Issue
2
Pages
266-273
ISSN
0042-6822 (ISSN-L)
OpenAlex
W2027674723
Cited by
293
References
1
FWCI
12.32
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The role of polyomaviruses in human disease. https://app.cochat.ai/papers/10.1016/j.virol.2008.09.027
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Jiang, M., Abend, J. R., Johnson, S. F., & Imperiale, M. J. (2009). The role of polyomaviruses in human disease. Virology. https://doi.org/10.1016/j.virol.2008.09.027

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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