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The role of reactive oxygen species and carbonate radical in oxcarbazepine degradation via UV, UV/H2O2: Kinetics, mechanisms and toxicity evaluation
Abstract
Oxcarbazepine (OXC) is ubiquitous in the aqueous environment. And due to its ecotoxicological effects and potential risks to human, an effective way to eliminate OXC from aqueous environment has aroused public concerns in recent years. Radical-based reactions have been shown to be an efficient way for OXC destruction, but the reactions of OXC with reactive oxygen species (ROS) and carbonate radical (CO 3•-) are still unclear. In this study, we focused the degradation of OXC and ROS, CO 3•- generation mechanism, and their roles in OXC degradation via UV and UV/H 2 O 2. The triplet state of oxcarbazepine (3 OXC∗) was found to play an important role in OXC degradation via UV. And hydroxyl radicals (•OH) and singlet oxygen (1 O 2) were found to be the dominant ROS in OXC degradation. Superoxide radical (O 2•-) did not react with OXC directly, but it may react with intermediate byproducts. Generation of CO 3•- played a positive role on OXC degradation for both UV and UV/H 2 O 2. In addition to •OH, 3 OXC* also contribute to CO 3•- production. The second-order rate constants of OXC with •OH and CO 3•- were 1.7 × 10 10 M-1 s-1 and 8.6 × 10 7 M-1 s-1, respectively. Potential OXC degradation mechanisms by •OH were proposed and included hydroxylation, α-ketol rearrangement, and benzylic acid rearrangement. Compared with non-selective •OH, the reactions involving CO 3•- are mainly electron transfer and hydrogen abstraction. And the acute toxicity of OXC was lower after UV/H 2 O 2 and UV/H 2 O 2/HCO 3- treatments, which was confirmed by luminescent bacterial assay (Vibrio fischeri bacterium).
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From Advanced Oxidation Processes for Degradation of Water Pollutants—Ambivalent Impact of Carbonate Species: A Review (2023) · cites this paper as [66]
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Metadata
- Authors
- Liu, T., Yin, K., Liu, C., Luo, J., Crittenden, J., Zhang, W., Luo, S., He, Q., Deng, Y., Liu, H., & Zhang, D.
- Affiliations
- Hunan University (CN)
- Georgia Institute of Technology (US)
- Corresponding author
- Luo, Jinming
- Venue
- Water Research
- Publisher
- Elsevier BV
- Published
- 2018-12
- Volume
- 147
- Pages
- 204-213
- ISSN
- 0043-1354 (ISSN-L)
- OpenAlex
- W2894887436
- Cited by
- 135
- References
- 72
- Citations by year
- 2026: 12 · 2025: 8 · 2024: 12 · 2023: 20 · 2022: 19 · 2021: 34 · 2020: 21 · 2019: 9
- FWCI
- 7.01
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Water Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (51478171, 51778218)
- Topics
- Physical Sciences › Environmental Science › Water Science and Technology › Advanced oxidation water treatment
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Water Treatment and Disinfection
- Physical Sciences › Environmental Science › Pollution › Pesticide and Herbicide Environmental Studies
- Keywords
- reactive oxygen species, carbonate radical, hydroxyl radicals, singlet oxygen, superoxide, triplet state, UV/H2O2, photodegradation mechanism, degradation kinetics, bicarbonate, acute toxicity, Vibrio fischeri, pharmaceutical pollutants
- MeSH terms
- Oxcarbazepine, Carbonates, Humans, Hydrogen Peroxide, Kinetics, Oxidation-Reduction, Ultraviolet Rays, Water Pollutants, Chemical, Reactive Oxygen Species, Hydroxyl Radical
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