Activity-dependent neuroprotective protein (ADNP) differentially interacts with chromatin to regulate genes essential for embryogenesis

Mandel, Shmuel, Rechavi, Gideon, Gozes, Illana·2007·Developmental Biology
DOI 10.1016/j.ydbio.2006.11.039

Cited by (167)

Items 101–167 of 167

  1. Microbiota changes associated with ADNP deficiencies: rapid indicators for NAP (CP201) treatment of the ADNP syndrome and beyond
    Oxana Kapitansky, Eliezer Giladi, Iman Jaljuli, Stefan Bereswill, Markus M. Heimesaat, Illana Gozes · 2020 · Journal of Neural Transmission
  2. Intranasal NAP (Davunetide): Neuroprotection and circadian rhythmicity
    Artur Galushkin, Illana Gozes · 2025 · Advanced Drug Delivery Reviews
  3. Alterations in Activity-Dependent Neuroprotective Protein in Sporadic and Experimental Parkinson’s Disease
    Yaping Chu, Gerardo A. Morfini, Jeffrey H. Kordower · 2016 · Journal of Parkinson s Disease
  4. Longitudinal ophthalmic findings in a child with Helsmoortel-Van der Aa Syndrome
    Michael J. Gale, Hope E. Titus, Gareth A. Harman, Talal Alabduljalil, Anna Dennis, Jenny L. Wilson, David M. Koeller, Erika L. Finanger, Peter A. Blasco, Pei-Wen Chiang et al. · 2018 · American Journal of Ophthalmology Case Reports
  5. Identification of a molecular network regulated by multiple ASD high risk genes
    Lei Wan, Guojun Yang, Zhen Yan · 2024 · Human Molecular Genetics
  6. The whole blood transcriptome at the time of maternal recognition of pregnancy in pigs reflects certain alterations in gene expression within the endometrium and the myometrium
    Bartosz Wojciechowicz, Justyna Kołakowska, Kamila Zglejc‐Waszak, Marcin Martyniak, Genowefa Kotwica, Anita Franczak · 2018 · Theriogenology
  7. STOP Codon Mutations at Sites of Natural Caspase Cleavage Are Implicated in Autism and Alzheimer’s Disease: The Case of ADNP
    Illana Gozes, Shula Shazman · 2022 · Frontiers in Endocrinology
  8. ADNP/ADNP2 expression in oligodendrocytes: implication for myelin-related neurodevelopment
    Anna Malishkevich, Janina Leyk, Olaf Goldbaum, Christiane Richter‐Landsberg, Illana Gozes · 2015 · Journal of Molecular Neuroscience
  9. Strong Correlation of Genome-Wide Expression after Traumatic Brain Injury In Vitro and In Vivo Implicates a Role for SORLA
    Michael R. Lamprecht, B. S. Elkin, K. Kesavabhotla, J. Crary, J. Hammers, Jimmy W. Huh, R. Raghupathi, B. Morrison · 2017 · Journal of Neurotrauma
  10. Bioinformatic prediction of putative conveyers of O-GlcNAc transferase intellectual disability
    Conor W. Mitchell, Ignacy Czajewski, Daan M. F. van Aalten · 2022 · Journal of Biological Chemistry
  11. Tau, ADNP , and sex
    Illana Gozes · 2023 · Cytoskeleton
  12. ADNP: A major autism mutated gene is differentially distributed (age and gender) in the songbird brain
    Gal Hacohen-Kleiman, Anat Barnea, Illana Gozes · 2015 · Peptides
  13. Specific protein biomarker patterns for Alzheimer’s disease: improved diagnostics in progress
    Illana Gozes · 2017 · The EPMA Journal
  14. Activity-Dependent Neuroprotective Protein (ADNP): An Overview of Its Role in the Eye
    Grazia Maugeri, Agata Grazia D’Amico, Benedetta Magrì, Giuseppe Musumeci, Velia D’Agata · 2022 · International Journal of Molecular Sciences
  15. Helsmoortel–van der Aa syndrome in a Chinese pediatric patient due to ADNP nonsense mutation: A case report
    Lijuan Chen, Zhong-min You, Wen-hong Chen, Si Yang, Chun-chen Feng, Haiyong Wang, Ting Wang, Yuanyuan Zhu · 2023 · Frontiers in Pediatrics
  16. Sex-and Region-Dependent Expression of the Autism-Linked ADNP Correlates with Social- and Speech-Related Genes in the Canary Brain
    Gal Hacohen-Kleiman, Stan Moaraf, Oxana Kapitansky, Illana Gozes · 2020 · Journal of Molecular Neuroscience
  17. Tracing the invisible mutant ADNP protein in Helsmoortel-Van der Aa syndrome patients
    Claudio Peter D’Incal, Elisa Cappuyns, Kaoutar Choukri, Kevin De Man, Kristy Szrama, Anthony Konings, Lina Bastini, Kim Van Meel, Amber Buys, Michele Gabriele et al. · 2024 · Scientific Reports
  18. Loss-of-function of activity-dependent neuroprotective protein (ADNP) by a splice-acceptor site mutation causes Helsmoortel–Van der Aa syndrome
    Claudio Peter D’Incal, Dale John Annear, Ellen Elinck, Jasper J. van der Smagt, Marielle M. Alders, Alexander J.M. Dingemans, Ligia Monica Mateiu, Bert B A De Vries, Wim Vanden Berghe, R. Frank Kooy · 2024 · European Journal of Human Genetics
  19. Novel features of Helsmoortel–Van der Aa/ADNP syndrome in a boy with a known pathogenic mutation in the ADNP gene detected by exome sequencing
    Chumei C. Li, Yong‐Dong Wang, Marta Szybowska · 2017 · American Journal of Medical Genetics Part A
  20. Protective inherited mutations in activity-dependent neuroprotective protein (ADNP): the good, the bad, and the ugly
    Illana Gozes, Shula Shazman, Eliezer Giladi, Joseph Levine · 2024 · Genomic psychiatry :
  21. Longitudinal Genotype-Phenotype (Vineland Questionnaire) Characterization of 15 ADNP Syndrome Cases Highlights Mutated Protein Length and Structural Characteristics Correlation with Communicative Abilities Accentuated in Males
    Jospeh Levine, Alexandra Lobyntseva, Shula Shazman, Fahed Hakim, Illana Gozes · 2024 · Journal of Molecular Neuroscience
  22. Single-cell analysis of cytoskeleton dynamics: From isoelectric focusing to live cell imaging and RNA-seq
    Illana Gozes, Yanina Ivashko‐Pachima, Oxana Kapitansky, Carmen Laura Sayas, Tal Iram · 2019 · Journal of Neuroscience Methods
  23. ChAHP2 and ChAHP control diverse retrotransposons by complementary activities
    Josip Ahel, Aparna Pandey, Michaela Schwaiger, Fabio Mohn, Anja Basters, Georg Kempf, Aude Andriollo, Lucas J. T. Kaaij, Daniel Heß, Marc Bühler · 2024 · Genes & Development
  24. Parkinson Disease-Modification Encompassing Rotenone and 6-Hydroxydopamine Neurotoxicity by the Microtubule-Protecting Drug Candidate SKIP
    Yanina Ivashko‐Pachima, Kim B. Seroogy, Yehonatan Sharabi, Illana Gozes · 2021 · Journal of Molecular Neuroscience
  25. Tau pathology: predictive diagnostics, targeted preventive and personalized medicine and application of advanced research in medical practice
    Illana Gozes · 2010 · The EPMA Journal
  26. Neuroprotective Drug Development: The Story of ADNP, NAP (Davunetide), and SKIP
    Illana Gozes · 2017 · Elsevier eBooks
  27. The Transcriptional Network Structure of a Myeloid Cell: A Computational Approach
    Jesús Espinal Enríquez, Daniel González-Terán, Enrique Hernandez Lemus · 2017 · International Journal of Genomics
  28. Episignatures stratifying ADNP syndrome show modest correlation with phenotype
    Michael S. Breen, Paras Garg, Lara Tang, Danielle Mendonca, Tess Levy, Mafalda Barbosa, Anne B. Arnett, Evangeline C. Kurtz‐Nelson, Emanuele Agolini, Agatino Battaglia et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  29. Systemic davunetide provides sex-specific neuroprotection during Coronary Artery Bypass Grafting (CABG)
    Illana Gozes, Jason Blatt, Liri Sophia Guz · 2025 · Translational Psychiatry
  30. Sex-Specific ADNP/NAP (Davunetide) Regulation of Cocaine-Induced Plasticity
    Yael Toren, Yarden Ziv, Shlomo Sragovich, Rebecca Anne McKinney, Segev Barak, Shula Shazman, Illana Gozes · 2024 · Journal of Molecular Neuroscience
  31. Microtubule stabilising peptides: new paradigm towards management of neuronal disorders
    Shubhangi Bhargava, Riya Kulkarni, Bhaskar Dewangan, Neeraj Kulkarni, Chirag Jiaswar, Kunal Kumar, Amit Kumar, Praveen Reddy Bodhe, Hemant Kumar, Bichismita Sahu · 2023 · RSC Medicinal Chemistry
  32. Protein Profiling Reveals Antioxidant and Signaling Activities of NAP (Davunetide) in Rodent Hippocampus Exposed to Hypobaric Hypoxia
    Niroj Kumar Sethy, Narendra Kumar Sharma, Mainak Das, Kalpana Bhargava · 2014 · Journal of Molecular Neuroscience
  33. From circadian sleep disruption to Neuroprotection: The potential of VIP/PACAP in Alzheimer’s disease treatment
    Artur Galushkin, Illana Gozes · 2024 · Current Research in Biotechnology
  34. Study of NAP adsorption and assembly on the surface of HOPG
    Vladimir V. Korolkov, Stephanie Allen, Clive J. Roberts, Illana Gozes, Saul J. B. Tendler · 2014 · Peptides
  35. Disentangling the role of tau pathology in autism spectrum disorders
    Francisca Villavicencio-Tejo, Margrethe A. Olesen, M. Leonardo Moya, Rodrigo A. Quintanilla · 2025 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  36. The ADNP-Mediated Transcriptome Response to Ketamine Impairs the Cytoskeletal Protein Axis
    Claudio Peter D’Incal, Ligia Monica Mateiu, Kevin De Man, Ellen Elinck, Illana Gozes, R. Frank Kooy · 2025 · Journal of Molecular Neuroscience
  37. ADNP Exhibits Methyltransferase Activity in Overexpression Systems and Modulates DNA and Histone Methylation
    Claudio Peter D’Incal, Kirsten Esther Van Rossem, Elisa Cappuyns, Anke Van Dijck, Ellen Elinck, Kevin De Man, Ayu Scott, Anthony Konings, Dale John Annear, R. Frank Kooy · 2025 · Autism Research
  38. Involvement of Vasoactive Intestinal Peptide Family Members in Diabetic Keratopathy
    Grazia Maugeri, Agata Grazia D’Amico, Benedetta Magrì, Velia D’Agata · 2024 · Applied Sciences
  39. Helsmoortel-Van der Aa syndrome in a 13-year-old girl with autistic spectrum disorder, dysmorphism, a right solitary kidney, and polycystic ovaries: a case report
    Ebtesam Al‐Enezi, Mohannad Ali Alghamdi, Khaled Alenezi, Mohammed A. Al Balwi, William Davies, Wafaa Eyaid · 2024 · Journal of Medical Case Reports
  40. POU3F2 regulates canonical Wnt signalling via SOX13 and ADNP to expand the neural progenitor population
    Courtney R. Benoit, Lilia B Sattler, Aimee J. Aylward, Olivia G. Pembridge, Bella Kim, Christina Muratore, Meichen Liao, Amy He, Nancy Ashour, Seeley B. Fancher et al. · 2025 · Brain
  41. Neuropeptide GPCRs in neuroendocrinology: the case of activity-dependent neuroprotective protein (ADNP)
    Illana Gozes · 2012 · Frontiers in Endocrinology
  42. Activity-dependent neuroprotective protein (ADNP)/NAP (CP201): Autism, schizophrenia, and Alzheimer’s disease
    Illana Gozes · 2019 · Elsevier eBooks
  43. ADNP missense variant p.C687R disrupts chromatin regulation and GABAergic differentiation in Helsmoortel–Van der Aa syndrome
    Qi Chen, Xixi Liu, Mengnan Wu, Daijing Sun, Xingyu Ding, Mengling Zhou, Wenzhu Peng, Yan Cheng, Biqing Xue, Ning Tang et al. · 2026 · Molecular Autism
  44. An Adnp frameshift variant disrupts Wnt signalling inducing chromatocytoskeletal defects and autism-related behaviour in male mice
    Claudio Peter D’Incal, Elisa Cappuyns, Flora Paldi, Mathijs B. van der Lei, Dale John Annear, Clara Milián Alastruey, Dimitra Sokolova, Ellen Elinck, Kevin De Man, Anthony Konings et al. · 2026 · EBioMedicine
  45. PACAP, VIP, and ADNP: Autism and Schizophrenia
    Illana Gozes · 2016 · Current topics in neurotoxicity
  46. Epigenetic Mechanisms of Autism Spectrum Disorders
    Zhen Yan · 2025 · Springer eBooks
  47. A frameshift variant in activity-dependent neuroprotective protein (ADNP) causes nucleocytoskeletal alterations in a dizygotic male twin: a case study
    Claudio Peter D’Incal, Anke Van Dijck, Dale John Annear, Lusine Harutyunyan, Ellen Elinck, Alexander J.M. Dingemans, Bert B A De Vries, Ligia Monica Mateiu, Marije E. C. Meuwissen, Anna Jansen et al. · 2025 · Clinical Epigenetics
  48. VIP–PACAP 2010: My Own Perspective on Modulation of Cognitive and Emotional Behavior
    Illana Gozes · 2010 · Journal of Molecular Neuroscience
  49. Use of Laccase-Producing Microorganisms in Membrane Systems for Polluting Agents Removal: Consideration and Perspectives
    Liliana Serna C, Fernando L Cuesta A · 2008 · Chilean journal of agricultural research
  50. Activity-Dependent Neuroprotective Protein (ADNP) and Davunetide (NAP)
    Illana Gozes, Peter W. Baas · 2013 · Elsevier eBooks
  51. Remodeling activity of ChAHP restricts transcription factor access to chromatin
    Josip Ahel, Fabio Mohn, Michaela Schwaiger, Jakob Schnabl-Baumgartner, Lucas J. T. Kaaij, Jennifer Steiner, Eliza Pandini Figueiredo Moreno, Daniel Heß, Marc Bühler · 2026 · Molecular Cell
  52. Modulation of axon excitable domains by astrocytes and microglia
    Juan José Garrido · 2026 · Frontiers in Cellular Neuroscience
  53. Expanding the Audiological Phenotype Associated With Activity‐Dependent Neuroprotective Protein ( ADNP ) Syndrome: A Case Report and Literature Review Suggesting a Genotype/Phenotype Correlation
    Kevin Carratu, Kelsey Crocker, Sharon Chen, Christine Moore, Neha Ashwin Patel, Ian D. Krantz · 2026 · American Journal of Medical Genetics Part A
  54. Aging ADNP syndrome mice exhibit mutation/sex-dependent disruption of motor behavior and circadian rhythmicity
    Artur Galushkin, Eliezer Giladi, Illana Gozes · 2026 · Neurobiology of Disease
  55. A potential combination therapy for traumatic brain injury: 17beta-estradiol and memantine
    Michael R. Lamprecht · 2015
  56. HP1 proteins safeguard embryonic stem cells
    Kristoffer N. Jensen, Matthew C. Lorincz · 2018 · Nature
  57. Editorial: A Child with ADNP Syndrome: A Case Study of Symptoms, Diagnostic Process and Innovative Behavioral Intervention Modes
    Miroslav Holec, Illana Gozes · 2025 · Journal of Molecular Neuroscience
  58. Identification and characterization of ADNP as a novel heterochromatin component
    Kerstin Mosch · 2011
  59. Antibody Production: Activity-Dependent Neuroprotective Protein (ADNP) as an Example
    Illana Gozes, Miri Holtser‐Cochav, Karin Vered · 2008 · Neuromethods
  60. The Cytoskeleton as a Pharmacological Target in Neurodegenerative Diseases
    Saar Oz, Illana Gozes · 2012 · Neuromethods
  61. BINDING OF HEAVY METAL IONS TO AMYLOID-? PEPTIDES: INTERACTIONS WITH NAP PEPTIDES
    Monica Jureschi · 2019 · International Multidisciplinary Scientific GeoConference SGEM ...
  62. 14-3-3 shuttles Activity-dependent neuroprotective protein to the cytoplasm to promote appropriate neuronal morphogenesis, cortical connectivity and calcium signaling
    Sarah A. Bennison, Sara M. Blazejewski, Xiaonan Liu, Kazuhito Toyo‐oka · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  63. Epigenetic Mechanisms of Autism Spectrum Disorders
    Zhen Yan · 2024 · Springer eBooks
  64. Methylation Profiling Provides Decisive Functional Evidence for Reclassifying an Adnp Variant of Uncertain Significance
    Gleyson Francisco da Silva Carvalho, Beatriz Martins Wolff, Lucas Liro Vieira, Mariana Ribeiro Costa, Rafaela da Silva Mendes, Eder Alencar Moura, Lissandro de Sousa Rolim, Karina Marinho Nascimento, Yanca Gasparini Oliveira, Rachel Sayuri Honjo et al. · 2025 · SSRN Electronic Journal
  65. ZNF787 recognizes the core sequence of MIR element to regulate gene expression
    Lingling Liao, Haining Zhou · 2025 · Molecular Biology of the Cell
  66. Dramatic sex differences leading to different brain disease presentation: The requirement for sex-specific medications with ADNP/davunetide as a case study
    Alexandra Lobyntseva, Liri Sophia Guz, Artur Galushkin, Illana Gozes · 2026 · Frontiers in Neuroendocrinology
  67. Syndromic Autism in Helsmoortel–Van der Aa Syndrome: From Clinical Suspicion to Genetic Diagnosis
    Fethiye Kılıçaslan, Özlem Öz, Ceylan Carık, Mehmet Burak Mutlu, Abdullah İhsan GÜRLER · 2026 · Developmental Neurobiology