The DOI matches its Crossref record; 95 of the 95 references it cites were found in a registry or an index.
Hox genes and regional patterning of the vertebrate body plan
Open accessAbstract
Several decades have passed since the discovery of Hox genes in the fruit fly Drosophila melanogaster. Their unique ability to regulate morphologies along the anteroposterior (AP) axis (Lewis, 1978) earned them well-deserved attention as important regulators of embryonic development. Phenotypes due to loss- and gain-of-function mutations in mouse Hox genes have revealed that the spatiotemporally controlled expression of these genes is critical for the correct morphogenesis of embryonic axial structures. Here, we review recent novel insight into the modalities of Hox protein function in imparting specific identity to anatomical regions of the vertebral column, and in controlling the emergence of these tissues concomitantly with providing them with axial identity. The control of these functions must have been intimately linked to the shaping of the body plan during evolution.
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Cites
A gene complex controlling segmentation in Drosophila
Lewis, E. B. (1978) · Nature · doi:10.1038/276565a0 · Cited by 3,812
Homeobox genes and axial patterning
McGinnis, W., & Krumlauf, R. (1992) · Cell · doi:10.1016/0092-8674(92)90471-n · Cited by 2,674
Graham, A., Papalopulu, N., & Krumlauf, R. (1989) · Cell · doi:10.1016/0092-8674(89)90912-4 · Cited by 1,024
Duboule, D., & Dollé, P. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb03534.x · Cited by 925
Clonal analysis of epiblast fate during germ layer formation in the mouse embryo
Lawson, K. A., Meneses, J. J., & Pedersen, R. A. (1991) · Development · doi:10.1242/dev.113.3.891 · Cited by 881
Expression pattern of the mouse T gene and its role in mesoderm formation
Wilkinson, D. G., Bhatt, S., & Herrmann, B. G. (1990) · Nature · doi:10.1038/343657a0 · Cited by 855
Hox genes and the evolution of vertebrate axial morphology
Burke, A. C., Nelson, C. E., Morgan, B. A., & Tabin, C. (1995) · Development · doi:10.1242/dev.121.2.333 · Cited by 851
Braun, T., Rudnicki, M. A., Arnold, H.-H., & Jaenisch, R. (1992) · Cell · doi:10.1016/0092-8674(92)90507-9 · Cited by 710
Soriano, P. (1997) · Development · doi:10.1242/dev.124.14.2691 · Cited by 707
Mrf4 determines skeletal muscle identity in Myf5:Myod double-mutant mice
Kassar-Duchossoy, L., Gayraud-Morel, B., Gomès, D., Rocancourt, D., Buckingham, M., Shinin, V., & Tajbakhsh, S. (2004) · Nature · doi:10.1038/nature02876 · Cited by 677
Cited by
Laganà, A. S., Vitale, S. G., Salmeri, F. M., Triolo, O., Ban Frangež, H., Vrtačnik-Bokal, E., Stojanovska, L., Apostolopoulos, V., Granese, R., & Sofo, V. (2017) · Medical Hypotheses · doi:10.1016/j.mehy.2017.03.032 · Cited by 221
Butcher, D. T., Cytrynbaum, C., Turinsky, A. L., Siu, M. T., Inbar-Feigenberg, M., Mendoza-Londono, R., Chitayat, D., Walker, S., Machado, J., Caluseriu, O., et al. (2017) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2017.04.004 · Cited by 200
HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis
Sun, Y., Zhou, B., Mao, F., Xu, J., Miao, H., Zou, Z., Phuc Khoa, L. T., Jang, Y., Cai, S., Witkin, M., et al. (2018) · Cancer Cell · doi:10.1016/j.ccell.2018.08.018 · Cited by 152
Stückemann, T., Cleland, J. P., Werner, S., Thi-Kim Vu, H., Bayersdorf, R., Liu, S.-Y., Friedrich, B., Jülicher, F., & Rink, J. C. (2017) · Developmental Cell · doi:10.1016/j.devcel.2016.12.024 · Cited by 133
Proteogenomic characterization and mapping of nucleosomes decoded by Brd and HP1 proteins
LeRoy, G., Chepelev, I., DiMaggio, P. A., Blanco, M. A., Zee, B. M., Zhao, K., & Garcia, B. A. (2012) · Genome Biology · doi:10.1186/gb-2012-13-8-r68 · Cited by 84
Metadata
- Authors
- Mallo, M., Wellik, D. M., & Deschamps, J.
- Venue
- Developmental Biology
- Publisher
- Elsevier BV
- Published
- 2010-08
- Volume
- 344
- Issue
- 1
- Pages
- 7-15
- ISSN
- 0012-1606 (ISSN-L)
- OpenAlex
- W2113300574
- Cited by
- 536
- References
- 95
- FWCI
- 10.16
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
