Cited by 215Psychosomatic Disorders and Their TreatmentsEpilepsy research and treatmentAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

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Cognitive behavioral therapy for psychogenic nonepileptic seizures

LaFrance, W. Curt, Miller, Ivan W., Ryan, Christine E., Blum, Andrew S., Solomon, David A., Kelley, Joan E., Keitner, Gabor I.·2009·Epilepsy & Behavior

DOI 10.1016/j.yebeh.2009.02.016

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Abstract

Treatment trials for psychogenic nonepileptic seizures (PNES) are few, despite the high prevalence and disabling nature of the disorder. We evaluated the effect of cognitive behavioral therapy (CBT) on reduction of PNES. Secondary measures included psychiatric symptom scales and psychosocial variables. We conducted a prospective clinical trial assessing the frequency of PNES in outpatients treated using a CBT for PNES manual. Subjects diagnosed with video/EEG-confirmed PNES were treated with CBT for PNES conducted in 12 weekly sessions. Seizure calendars were charted prospectively. Twenty-one subjects enrolled, and 17 (81%) completed the CBT intervention. Eleven of the 17 completers reported no seizures by their final CBT session. Mean scores on scales of depression, anxiety, somatic symptoms, quality of life, and psychosocial functioning showed improvement from baseline to final session. CBT for PNES reduced the number of PNES and improved psychiatric symptoms, psychosocial functioning, and quality of life.

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LaFrance Jr WC, Blum AS, Ryan CE, Miller IW, Keitner GI. Abstract P07.012. Comorbidities in patients with psychogenic nonepileptic seizures. Neurology 2009; in press.

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Authors: LaFrance, W. C., Miller, I. W., Ryan, C. E., Blum, A. S., Solomon, D. A., Kelley, J. E., & Keitner, G. I.
Affiliations: Brown University (US)
ORCID: Blum, Andrew S.
Venue: Epilepsy & Behavior
Publisher: Elsevier BV
Published: 2009-04
Volume: 14
Issue: 4
Pages: 591-596
ISSN: 1525-5050 (ISSN-L)
DOI: 10.1016/j.yebeh.2009.02.016
OpenAlex: W2065657467
Cited by: 215
References: 55
Citations by year: 2026: 11 · 2025: 8 · 2024: 3 · 2023: 9 · 2022: 7 · 2021: 9 · 2020: 20 · 2019: 7 · 2018: 14 · 2017: 9 · 2016: 8 · 2015: 15 · 2014: 24 · 2013: 20 · 2012: 18
FWCI: 10.28
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
doi.org/10.15223/policy-017 (stm-asf)
doi.org/10.15223/policy-037 (stm-asf)
doi.org/10.15223/policy-012 (stm-asf)
doi.org/10.15223/policy-029 (stm-asf)
doi.org/10.15223/policy-004 (stm-asf)
Locations: Epilepsy & Behavior (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Neurological Disorders and Stroke
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Health Sciences › Medicine › Clinical Neurology › Epilepsy research and treatment
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords: psychogenic non-epileptic seizures, cognitive behavioral therapy, seizure frequency reduction, psychiatric symptoms, depression, anxiety, somatic symptoms, quality of life, psychosocial functioning
MeSH terms: Adult, Electroencephalography, Female, Humans, Male, Middle Aged, Prospective Studies, Psychiatric Status Rating Scales, Psychophysiologic Disorders, Quality of Life, Retrospective Studies, Seizures, Video Recording, Cognitive Behavioral Therapy, Chi-Square Distribution, Treatment Outcome, Statistics, Nonparametric

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Cognitive behavioral therapy for psychogenic nonepileptic seizures

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