The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Virus-like particles: Passport to immune recognition
Open accessAbstract
Virus-like particles (VLPs) are formed by the self-assembly of envelope and/or capsid proteins from many viruses. In many cases such VLPs have structural characteristics and antigenicity similar to the parental virus, and some have already proven successful as vaccines against the cognate virus infection. The structural components of some VLPs have also proven amenable to the insertion or fusion of foreign antigenic sequences, allowing the production of chimeric VLPs exposing the foreign antigen on their surface. Other VLPs have been used as carriers for foreign antigens, including non-protein antigens, via chemical conjugation. This review outlines some of the advantages, disadvantages, and technical considerations for the use of a wide range of VLP systems in vaccine development.
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Cites
Maurer, P., Jennings, G. T., Willers, J., Rohner, F., Lindman, Y., Roubicek, K., Renner, W. A., Müller, P., & Bachmann, M. F. (2005) · European Journal of Immunology · doi:10.1002/eji.200526285 · Cited by 279
Bräutigam, S., Snezhkov, E., & Bishop, D. H. L. (1993) · Virology · doi:10.1006/viro.1993.1067 · Cited by 72
Cited by
Bio-inspired, bioengineered and biomimetic drug delivery carriers
Yoo, J.-W., Irvine, D. J., Discher, D. E., & Mitragotri, S. (2011) · Nature Reviews Drug Discovery · doi:10.1038/nrd3499 · Cited by 1,236
Virus-like particles in vaccine development
Roldão, A., Mellado, M. C. M., Castilho, L. R., Carrondo, M. J., & Alves, P. M. (2010) · Expert Review of Vaccines · doi:10.1586/erv.10.115 · Cited by 845
Kushnir, N., Streatfield, S. J., & Yusibov, V. (2012) · Vaccine · doi:10.1016/j.vaccine.2012.10.083 · Cited by 587
D’Aoust, M., Couture, M. M. ‐., Charland, N., Trépanier, S., Landry, N., Ors, F., & Vézina, L. (2010) · Plant Biotechnology Journal · doi:10.1111/j.1467-7652.2009.00496.x · Cited by 371
Self-assembling protein nanoparticles in the design of vaccines
López-Sagaseta, J., Malito, E., Rappuoli, R., & Bottomley, M. J. (2016) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2015.11.001 · Cited by 353
Metadata
- Authors
- Grgacic, E. V. L., & Anderson, D. A.
- Venue
- Methods
- Publisher
- Elsevier BV
- Published
- 2006-09
- Volume
- 40
- Issue
- 1
- Pages
- 60-65
- ISSN
- 1046-2023 (ISSN-L)
- OpenAlex
- W2075515367
- Cited by
- 582
- References
- 2
- FWCI
- 6.63
- Type
- journal article
- Language
- en
- Open access
- green
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