Extracellular Vesicles Containing IL-4 Modulate Neuroinflammation in a Mouse Model of Multiple Sclerosis

Casella, Giacomo, Colombo, Federico, Finardi, Annamaria, Descamps, Hélène, Ill-Raga, Gerard, Spinelli, Antonello, Podini, Paola, Bastoni, Mattia +3 more·2018·Molecular Therapy

Cited by (134)

Items 101–134 of 134

  1. A vivid outline demonstrating the benefits of exosome-mediated drug delivery in CNS-associated disease environments
    Rachayeeta Ray, Sougata Ghosh Chowdhury, Parimal Karmakar · 2024 · Archives of Biochemistry and Biophysics
  2. Human platelet lysate: a potential therapeutic for intracerebral hemorrhage
    Dachang Qiu, Lin Wang, Lanlan Wang, Yongfei Dong · 2025 · Frontiers in Neuroscience
  3. Coenzyme Q 10 and the exclusive club of diseases that show a limited response to treatment
    Nadia Turton, Nathan L. Bowers, Sam Khajeh, Iain Parry Hargreaves, Robert A. Heaton · 2021 · Expert Opinion on Orphan Drugs
  4. Engineered nerve guide conduit enhances peripheral nerve regeneration by modulating the microenvironment through macrophage-triggered cascade reactions
    Xindi Yang, Xiao Liang, Binyi Wang, Xing Gao, Wenqiang Yang, Jiajun Li, Huaan Cai, Zan Tong, Yun Chen · 2025 · Bioactive Materials
  5. Decoding the molecular and cellular aspects of multiple sclerosis: From diagnosis to therapeutic strategies
    Nancy Sanjay Gupta, Shubham Kumar Shrivastav, Indrakant Kumar Singh, Smita Kumari, Niraj Kumar Jha, Rohan Gupta · 2025 · Brain Research
  6. Extracellular Vesicles in Chronic Demyelinating Diseases: Prospects in Treatment and Diagnosis of Autoimmune Neurological Disorders
    Leyla A. Ovchinnikova, Arthur O. Zalevsky, Yakov A. Lomakin · 2022 · Life
  7. Vesicles: New Advances in the Treatment of Neurodegenerative Diseases
    Domenico Nuzzo, Antonella Girgenti, Laura Palumbo, Flores Naselli, Martina Bavetta, Giovanni Marfia, Pasquale Picone · 2024 · International Journal of Molecular Sciences
  8. Engineered extracellular vesicles for TGF-β encapsulation as a therapeutic strategy against LPS-induced systemic inflammation
    Zhuo-Hua Zhao, Bo Huang, Zi-Han Fang, Wen-Hui Qi, Jinpeng He, Li‐Bin Wang, Yuan Zhang, Xing Li · 2025 · International Immunopharmacology
  9. MFG‐E8 in Microglial Regulation: A Review of Basic Research in the Central Nervous System
    Dan Li, Weihong Lu, Rongchun Wang, Ying Ma · 2025 · Journal of Food Science
  10. Roles of glia-derived extracellular vesicles in central nervous system diseases: an update
    Hao Sun, Xiaojuan Su, Shiping Li, Dezhi Mu, Yi Qu · 2021 · Reviews in the Neurosciences
  11. Role of Thrombosis in Neurodegenerative Diseases: An Intricate Mechanism of Neurovascular Complications
    Samir Kumar Beura, Abhishek Ramachandra Panigrahi, Pooja Yadav, Paresh Prahlad Kulkarni, Vikas Lakhanpal, Bhupinder Singh, Sunil Kumar Singh · 2024 · Molecular Neurobiology
  12. Revolutionizing therapeutics: unleashing the power of extracellular vesicles for disease intervention
    Sayam Ghosal, Bernadett R. Bodnár, Brachyahu Meir Kestecher, Ákos Nagy, Tamás László, Bora Yilmaz, Yixuan Zeng, Adrienn Szabó, Csaba Bödör, Edit I. Buzás et al. · 2025 · Current Opinion in Physiology
  13. Olig2-enriched exosomes: A novel therapeutic approach for cuprizone-induced demyelination
    Yongjun Li, Jin Mei He, Qinghua Zhang, Bo Wei, Xiang Tao, Cheng-Chao Yu, Lina Shi, Zhenhai Wang, Xing Li, Li‐Bin Wang · 2024 · Neuroscience
  14. A specific and adaptable approach to track CD206+ macrophages by molecular MRI and fluorescence imaging
    Cuihua Wang, Negin Jalali Motlagh, Gregory R. Wojtkiewicz, Hongzhi Yang, Hyung-Hwan Kim, John W. Chen · 2024 · Theranostics
  15. Extracellular vesicles as a promising tool in neuropsychiatric pharmacotherapy application and monitoring
    Nikola Balic, Matea Nikolac Perković, Tina Milos, Barbara Vuić, Matea Kurtovic Kodzoman, Dubravka Švob Štrac, Gordana Nedić Erjavec · 2025 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  16. Single‐Cell Analysis of L‐Myc Expressing Neural Stem Cells and Their Extracellular Vesicles Revealed Distinct Progenitor Populations With Neurogenic Potential
    Patrick Pirrotte, Yate‐Ching Yuan, Nathaniel P. Hansen, Isabella Vasquez, Nan Jiang, Alejandra Velazquez Ojeda, Eric B. Alsop, Melissa N. Martinez, Ritin Sharma, Meechoovet Hunsar et al. · 2025 · Journal of Extracellular Biology
  17. Vesicular Rps6 Released by Astrocytes in an Experimental Model of AD Regulates Local Translation and Enhances Synaptic Integrity in Neurones
    María Gamarra, Aida de la Cruz‐Gambra, Maite Blanco‐Urrejola, Esperanza González, Mikel Azkargorta, Felix Elortza, Juan Manuel Falcón‐Pérez, Jimena Baleriola · 2025 · Journal of Extracellular Vesicles
  18. Extracellular vesicles as minimally invasive biomarkers and therapeutic platforms in rare neurological diseases
    Nathan D. Phan, Raghu Rai Sharma, Subbaya Subramanian, Reena V. Kartha · 2026 · Frontiers in Aging
  19. Stem Cell-Derived Extracellular Vesicles (EVs) for Disease Therapy
    Qing Li, Cheng Ji, Yu Chen, Xinyu Niu, Fengtian Sun, Siqi Yin, Hui Shi, Teng Ye, Zhengsheng Chen, Zhifeng Deng et al. · 2024 · Springer eBooks
  20. Les vésicules extracellulaires
    Élodie Leroux, Romain Perbet, Luc Buée, Morvane Colin · 2021 · médecine/sciences
  21. Exosome-mediated co-delivery of superoxide dismutase and chondroitinase ABC for multiple sclerosis therapy
    Xinxin Shao, Xinxin Feng, Jinran Feng, Tianyuan Qiu, Shengcai Yang, Quanshun Li · 2025 · International Journal of Biological Macromolecules
  22. Microglial exosomes: taking messaging to new spheres
    Deborah Kronenberg‐Versteeg, Balazs Viktor Varga · 2021 · Brain Communications
  23. Advanced engineering strategies of extracellular vesicles for enhanced central nervous system regeneration and disease modulation
    Joshua B. Stein, Munaifa Arif, Hyein Cheung, Ki‐Bum Lee · 2026 · Cell Biomaterials
  24. Neurodegenerative Disorder and Fine Particulate Matter
    Hironori Kawahara, Rikinari Hanayama · 2025 · Springer eBooks
  25. Differential impact of inflammasome-induced extracellular vesicles on immune cells: key control by the functional state of the recipient cell
    Claudia Verderio, Marta Lombardi, Francesco Di Virgilio · 2021 · ExRNA
  26. Faculty Opinions recommendation of Extracellular vesicle-encapsulated IL-10 as novel nanotherapeutics against ischemic AKI.
    Yanlin Wang · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  27. Targeted Drug Delivery to ACE2+ Cells Using Engineered Extracellular Vesicles: A Potential Therapeutic Approach for COVID-19
    Yao Zhang, Sheng‐Jiao Song, Jin Mei He, Zhuo-Hua Zhao, Ke Zhang, Yuan Zhang, Xing Li · 2024 · Current Pharmaceutical Biotechnology
  28. Targeting Cytokines: Evaluating the Potential of Mesenchymal Stem Cell Derived Extracellular Vesicles in the Management of COVID-19
    Iago Carvalho Schultz, Ana Cláudia dos Santos Pereira Andrade, Isabelle Dubuc, Audrée Laroche, Isabelle Allaeys, Étienne Doré, Nicolas Bertrand, Luc Vallières, Julie Fradette, Louis Flamand et al. · 2024 · Stem Cell Reviews and Reports
  29. Neuronal Distribution of Tau Pathology, Microglial Gene Expression Trajectories, and Resilience to Alzheimer disease
    Sunny Kumar, Ana Claudia Silva Amaral, Cinthya Agüero, Charles Zachary Klein, Michael Siao Tick Chong, Prianca Ramanan, Margaret Scapellato, Riddhimaa Sinha, Julie A Schneider, David Bennett et al. · 2025 · medRxiv
  30. Blood cytokine levels in anti-NMDAR and viral encephalitis during the early stage of hospitalization: a small-sample exploratory pilot study
    Yingshi Guo, Yingzhu Zhao, Yujie Yi, Hong Zhou, Kaiye Xing, Yan Yu, Jie Wang · 2026 · Frontiers in Immunology
  31. Extracellular Vesicle‐Associated IL4 Displays Enhanced Anti‐Inflammatory Properties in Microglial Cells
    Giulia Marostica, Chiara Frigé, Annamaria Finardi, Alessandra Mandelli, Susanna Manenti, Stella Siciliani, Paola Podini, Ivan de Curtis, Luca Muzio, E D Rossi et al. · 2026 · Journal of Extracellular Biology
  32. Harnessing macrophage signaling pathways and scalable engineering for next-generation immunotherapies
    Daniela Paasch, Kathrin Haake, Chloe Kan, Cristiana Ulpiano, Eirini Nikolouli, Mi-Sun Jang, Mark-Christian Klassen, Michael Epstein, Ryohichi Sugimura, Nico Lachmann · 2026 · Signal Transduction and Targeted Therapy
  33. Exosomal innovations in neurodegenerative disorders: Emerging insights and intranasal route
    Rajashree Shreeram Hirlekar, Srushti Agnihotri, Shalom Sathe, Mangal Nagarsenkar · 2026 · Biochemical and Biophysical Research Communications
  34. The Roles and Uses of Extracellular Vesicles in Neuroimmunologic Diseases
    Ryan Kammeyer, Christina M. Coughlan · 2026 · Journal of Neuroscience