Origin of endometriosis from the mesenchyme of the celomic walls
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The retrograde menstruation and implantation theory does not explain all clinical observations, such as extragenital endometriosis, endometriosis in women without endometrium and in men, or the clonal aspect.
“The retrograde menstruation and implantation theory does not explain all clinical observations (Table 1), such as extragenital endometriosis (220), endometriosis in women without endometrium (31) and in men (33), or the clonal aspect (149).”
From Pathogenesis of endometriosis: The genetic/epigenetic theory (2019) · cites this paper as [31]
The metaplasia theory was a histologic observation that did not consider genetic or epigenetic changes.
“The implantation theory (1, 11, 201) was a reasonable hypothesis when formulated, while the metaplasia theory (31) was a histologic observation that did not consider genetic or epigenetic changes.”
From Pathogenesis of endometriosis: The genetic/epigenetic theory (2019) · cites this paper as [31]
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References 3 · Cited by 179
- Authors
- Gruenwald, P.
- Corresponding author
- Gruenwald, Peter
- Venue
- American Journal of Obstetrics and Gynecology
- Publisher
- Elsevier BV
- Published
- 1942-09
- Volume
- 44
- Issue
- 3
- Pages
- 470-474
- ISSN
- 0002-9378 (ISSN-L)
- OpenAlex
- W1526062852
- Cited by
- 179
- References
- 3
- Citations by year
- 2026: 5 · 2025: 7 · 2024: 16 · 2023: 11 · 2022: 9 · 2021: 10 · 2020: 8 · 2019: 4 · 2018: 5 · 2017: 6 · 2016: 6 · 2015: 7 · 2014: 6 · 2013: 5
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Obstetrics and Gynecology (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ectopic Pregnancy Diagnosis and Management
- Keywords
- endometriosis, mesenchyme, Müllerian ducts, embryology, uterine epithelium, ectopic endometrium
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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