The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Fiber Orientation and Ejection Fraction in the Human Left Ventricle
Open accessAbstract
Fiber orientation and ventricular geometry are incorporated in a mathematical model for ejection fraction of the human left ventricle. The inadequacy of circularly oriented or "constrictor" fibers to explain high ejection fractions of cylindrical, spherical, or ellipsoidal reference ventricles is demonstrated. A class of "helical" fibers is then introduced from which ejection fractions predicted by physiologic amounts of fiber shortening on cylindrical and ellipsoidal reference ventricles are shown to be consistent with those calculated from biplane angio-cardiographic films.
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“Overall, these results were consistent with the projections of previous analytical and computational models (3, 25, 36) in that they showed more-homogeneous deformations for HA ventricles.”
From Recreating the heart's helical structure-function relationship with focused rotary jet spinning (2022) · cites this paper as [3]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“It has been predicted that EFs should scale as 1 – k2 for CA ventricles (eq. S5) and 1 - k2 q H(α) for HA ventricles (eq. S15) (Fig. 2D) (3), with k being the strain along the fiber axis, q being the apical shortening, and H(α) being the radial shortening based on the fiber’s helical angle (eqs. S5 to S15).”
From Recreating the heart's helical structure-function relationship with focused rotary jet spinning (2022) · cites this paper as [3]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
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“It has been hypothesized that HA ventricles would display increased apical shortening (3, 36) and reduced basal displacement (9, 36), owing to differences in myofiber lengths.”
From Recreating the heart's helical structure-function relationship with focused rotary jet spinning (2022) · cites this paper as [3]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Sallin’s model predicted an EF increase of 54 to 64% for HA ventricles, which was consistent with our experimental observations (within the standard error of the mean; Fig. 3E).”
From Recreating the heart's helical structure-function relationship with focused rotary jet spinning (2022) · cites this paper as [3]
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“showing that the biomechanics of these single-layer ventricle models is consistent with theoretical predictions from the past 50 years (3, 4, 25).”
From Recreating the heart's helical structure-function relationship with focused rotary jet spinning (2022) · cites this paper as [3]
The cited source says what the claim attributes to it.
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“Over the past half-century, it has been argued that this helical arrangement represents a fundamental structural design critical to achieving large ejection fractions (EFs) (1, 3–6).”
From Recreating the heart's helical structure-function relationship with focused rotary jet spinning (2022) · cites this paper as [3]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
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“Scaling Sallin’s model to physiological relevant strains (~15 to 20%) (3), we noted that single-angle ventricles could achieve EFs of only up to ~43% (α = 30°) (see supplementary materials for details).”
From Recreating the heart's helical structure-function relationship with focused rotary jet spinning (2022) · cites this paper as [3]
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Citations
Cites
Fiber Orientation in the Canine Left Ventricle during Diastole and Systole
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Metadata
- Authors
- Sallin, E. A.
- Affiliations
- University of Alabama (US)
- Corresponding author
- Sallin, Edward A.
- Venue
- Biophysical Journal
- Publisher
- Elsevier BV
- Published
- 1969-07
- Volume
- 9
- Issue
- 7
- Pages
- 954-964
- ISSN
- 0006-3495 (ISSN-L)
- PMC
- PMC1367490
- OpenAlex
- W1994976809
- Cited by
- 240
- References
- 8
- Citations by year
- 2026: 5 · 2025: 9 · 2024: 9 · 2023: 9 · 2022: 12 · 2021: 5 · 2020: 10 · 2019: 7 · 2018: 12 · 2017: 18 · 2016: 10 · 2015: 8 · 2014: 12 · 2013: 5 · 2012: 7
- FWCI
- 2.66
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Biophysical Journal (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiomyopathy and Myosin Studies
- Physical Sciences › Engineering › Biomedical Engineering › Elasticity and Material Modeling
- Keywords
- left ventricle, ejection fraction, myocardial fiber orientation, helical fibers, ventricular geometry, fiber shortening
- MeSH terms
- Heart, Models, Biological, Ventricular Function
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