Trimethylamine‐ N ‐oxide‐induced folding of α‐synuclein

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Strategic Modulation of Polarity and Viscosity Sensitivity of Bimane Molecular Rotor-Based Fluorophores for Imaging α-Synuclein

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Solution Model of the Intrinsically Disordered Polyglutamine Tract-Binding Protein-1

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Dequalinium-induced Protofibril Formation of α-Synuclein

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Interaction with zinc oxide nanoparticle kinetically traps α-synuclein fibrillation into off-pathway non-toxic intermediates

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Gut–brain axis and environmental factors in Parkinson’s disease: bidirectional link between disease onset and progression

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Osmolyte mixtures have different effects than individual osmolytes on protein folding and functional activity

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Calibrated Langevin-dynamics simulations of intrinsically disordered proteins

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Sucrose prevents protein fibrillation through compaction of the tertiary structure but hardly affects the secondary structure

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Microscopic significance of hydrophobic residues in the protein-stabilizing effect of trimethylamine N-oxide (TMAO)

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Probing the Nongeneralized Amyloid Inhibitory Mechanism of Hydrophobic Chaperone

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Persistent homology analysis of osmolyte molecular aggregation and their hydrogen-bonding networks

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Protein Fibrillation under Crowded Conditions

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α-synuclein overexpression and the microbiome shape the gut and brain metabolome in mice

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Fully reduced granulin-B is intrinsically disordered and displays concentration-dependent dynamics

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Modulation of the Activity of Newly Synthesized Human Phenylalanine Hydroxylase Mutant Proteins by Low-Molecular-Weight Compounds

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DnaK/DnaJ/GrpE of Hsp70 system have differing effects on α-synuclein fibrillation involved in Parkinson's disease

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Decoding TMAO in the Gut-Organ Axis: From Biomarkers and Cell Death Mechanisms to Therapeutic Horizons

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Disorder-to-order transitions in the molten globule-like Golgi Reassembly and Stacking Protein

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Cosolvent Effects on the Growth of Protein Aggregates Formed by a Single Domain Globular Protein and an Intrinsically Disordered Protein

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Cosolvent effects on the growth of amyloid fibrils

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The gut metabolite, trimethylamine N-oxide inhibits protein folding by affecting cis–trans isomerization and induces cell cycle arrest

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Natural osmolytes alleviate GRP78 and ATF-4 levels: Corroboration for potential modulators of unfolded protein response

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Isolation of short peptide fragments from α-synuclein fibril core identifies a residue important for fibril nucleation: A possible implication for diagnostic applications

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Untangling the interaction of α-synuclein with DNA i-motifs and hairpins by volume-sensitive single-molecule FRET spectroscopy

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Osmolyte Effects on the Growth of Amyloid Fibrils

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Effect of Osmolytes on the Conformational Behavior of a Macromolecule in a Cytoplasm-like Crowded Environment: A Femtosecond Mid-IR Pump–Probe Spectroscopy Study

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Protein Misfolding in Lipid-Mimetic Environments

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A chemical chaperone induces inhomogeneous conformational changes in flexible proteins

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Structural and Conformational Prerequisites of Amyloidogenesis

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The Determination of Trimethylamine N-Oxide and Organic Acids Connected with Gut Microbiota in the Urine of Parkinson’s Disease Patients: A Pilot Study

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Kinetic control in amyloid polymorphism: Different agitation and solution conditions promote distinct amyloid polymorphs of alpha-synuclein

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Variants in the CETP gene affect levels of HDL cholesterol by reducing the amount, and not the specific lipid transfer activity, of secreted CETP

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TMAO to the rescue of pathogenic protein variants

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Urea ameliorates trimethylamine N-oxide-Induced aggregation of intrinsically disordered α-casein protein: the other side of the urea-methylamine counteraction

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Factors Affecting the Fibrillation of α-Synuclein, a Natively Unfolded Protein

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Probing the Conformational Ensemble of the Amyloid Beta 16–22 Fragment with Parallel-Bias Metadynamics

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Role of Osmolytes in Amyloidosis

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Effects of Ions and Small Compounds on the Structure of Aβ42 Monomers

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Pathways to Amyloid Fibril Formation: Partially Folded Intermediates in the Fibrillation of Natively Unfolded Proteins

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Cross-Linking and Covalent Labeling Mass Spectrometry Reveal Proteoform-Driven Conformational Changes in Alpha Synuclein

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Modulation of conformational integrity and aggregation propensity of α-synuclein by osmolytes: Implications in therapeutic intervention of Parkinson’s disease

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α-Synuclein Fibrils as Penrose Machines: A Chameleon in the Gear

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Critical Role of Zinc Ion on E. coli Glutamyl-Queuosine-tRNAAsp Synthetase (Glu-Q-RS) Structure and Function

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Metabolic Disturbances in the Gut-brain Axis of a Mouse Model of MPTP-induced Parkinsonism Evaluated by Nuclear Magnetic Resonance

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Factors responsible for alpha-Synuclein aggregation

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Metabolomics: a new frontier in neurodegenerative disease biomarker discovery

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Quest for space: Tenacity of DNA, Protein, and Lipid macromolecules in intracellular crowded environment

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Exploring the Transition of Human α-Synuclein from Native to the Fibrillar State: Insights into the Pathogenesis of Parkinson’s Disease

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Protein Refolding/Renaturation

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Characterization of the mechanisms by which missense mutations in the lysosomal acid lipase gene disrupt enzymatic activity

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Modifiers of Protein Aggregation—From Nonspecific to Specific Interactions

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Macromolecular crowding: how it affects protein structure, disorder, and catalysis

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Halophilic Properties and their Manipulation and Application

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Role of TMAO on Folding Behavior of Various Proteins Associated with Neurodegeneration

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Methods for measuring structural disorder in proteins

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Effect of ethanol as molecular crowding agent on the conformational dynamics of α-synuclein

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Small Molecule Osmolytes Can Modulate Proteostasis

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Modulation of Protein Aggregation/Fibrillation by Osmolytes

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A30P and A30G Mutations in α-Synuclein Promote Metastable Long-Lived Aggregates with Distinct Structural Responses to EGCG

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Trimethylamine N-oxide participates in human diseases by causing endoplasmic reticulum stress

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Osmolyte-Mediated Protein Stabilization: Unraveling Interactions Across Conformational Landscapes

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Therapeutic approaches in proteinopathies

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Association Between Blood-Brain Barrier Disruption and Gut Microbiota Dysbiosis in Parkinson’s Disease

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The gut–brain axis and trimethylamine N-oxide: an emergent biomarker in neurological diseases

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Parkinson’s disease and inflammatory bowel disease: exploring the connection between the two

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