The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Citrulline, a novel compatible solute in drought‐tolerant wild watermelon leaves, is an efficient hydroxyl radical scavenger
Open accessAbstract
Drought‐tolerant wild watermelon accumulates high levels of citrulline in the leaves in response to drought conditions. In this work, the hydroxyl radical‐scavenging activity of citrulline was investigated in vitro. The second‐order rate constant for the reaction between citrulline and hydroxyl radicals was found to be 3.9×10 9 M−1 s−1, demonstrating that citrulline is one of the most efficient scavengers among compatible solutes examined so far. Moreover, citrulline effectively protected DNA and an enzyme from oxidative injuries. Liquid chromatography‐mass spectrometry analysis revealed that at least four major products were formed by the reaction between citrulline and hydroxyl radicals. Activities of metabolic enzymes were not inhibited by up to 600 mM citrulline, indicating that citrulline does not interfere with cellular metabolism. We reasoned, from these results, that citrulline contributes to oxidative stress tolerance under drought conditions as a novel hydroxyl radical scavenger.
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Almost all about citrulline in mammals
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Metadata
- Authors
- Akashi, K., Miyake, C., & Yokota, A.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 2001-11-09
- Volume
- 508
- Issue
- 3
- Pages
- 438-442
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2008593502
- Cited by
- 254
- References
- 25
- FWCI
- 6.62
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Akashi, K., Miyake, C., & Yokota, A. (2001). Citrulline, a novel compatible solute in drought‐tolerant wild watermelon leaves, is an efficient hydroxyl radical scavenger. FEBS Letters. https://doi.org/10.1016/s0014-5793(01)03123-4
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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