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Cited by 379

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Structural characterization of human erythropoietin.

Open access
Lai, P H, Everett, R, Wang, F F, Arakawa, T, Goldwasser, E·1986·Journal of Biological Chemistry

Abstract

Erythropoietin is the primary regulator of red blood cell formation in mammals. Because of its extreme scarcity, very little information is available regarding structural features of this important glycoprotein. We report here the primary structure of human urinary erythropoietin, determined by protein sequencing. In addition, the sites of glycosylation, assignment of disulfide bonds, and the circular dichroism of the hormone analyzed for secondary structure in comparison with the prediction from the sequence are presented.

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Crossref · 10.1016/s0021-9258(17)35756-3

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Metadata

Authors
Lai, P. H., Everett, R., Wang, F. F., Arakawa, T., & Goldwasser, E.
Venue
Journal of Biological Chemistry
Publisher
Elsevier BV
Published
1986-03
Volume
261
Issue
7
Pages
3116-3121
ISSN
0021-9258 (ISSN-L)
OpenAlex
W1493841569
Cited by
379
References
0
FWCI
8.94
Type
journal article
Language
en
Open access
hybrid

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.