The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Retinoids and vertebrate development.
Open accessAbstract
In conclusion, it is obvious that many of the abnormalities in pattern formation and organ formation that result from the exogenous addition of RA during embryogenesis are related at least in part to the ability of RA to change the pattern of expression of the clusters of homeobox genes in the mammalian embryo. The majority of experimental protocols to study RA-induced changes in embryonic development have utilized treatments with excess, exogenous RA, but it has not yet been proven that endogenous RA acts as a key signaling molecule in developing embryo. Thus, we need to develop an understanding of the metabolic enzymes that control the levels of the important endogenous retinoids, including RA, in the developing embryo. The continuing study of retinoids and their receptors will provide us with significant new information about the regulatory programs that control differentiation and development. Moreover, these studies will lead to discoveries relevant to the clinical use of retinoids in the areas of cancer prevention and treatment, and dermatology.
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Lammer, E. J., Chen, D. T., Hoar, R. M., Agnish, N. D., Benke, P. J., Braun, J. T., Curry, C. J., Fernhoff, P. M., Grix, A. W., Lott, I. T., et al. (1985) · New England Journal of Medicine · doi:10.1056/nejm198510033131401 · Cited by 1,942
Multiplicity generates diversity in the retinoic acid signalling pathways
Leid, M., Kastner, P., & Chambon, P. (1992) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(92)90014-z · Cited by 821
Cited by
Transcription Factors, Normal Myeloid Development, and Leukemia
Tenen, D. G., Hromas, R., Licht, J. D., & Zhang, D.-E. (1997) · Blood · doi:10.1182/blood.v90.2.489 · Cited by 735
Retinoids, Retinoic Acid Receptors, and Cancer
Tang, X.-H., & Gudas, L. J. (2011) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathol-011110-130303 · Cited by 596
Self-citationRole of Hormones in Pilosebaceous Unit Development
Deplewski, D., & Rosenfield, R. L. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.4.0404 · Cited by 443
Retinoids regulate stem cell differentiation
Gudas, L. J., & Wagner, J. A. (2011) · Journal of Cellular Physiology · doi:10.1002/jcp.22417 · Cited by 395
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Metadata
- Authors
- Gudas, L. J.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1994-06
- Volume
- 269
- Issue
- 22
- Pages
- 15399-15402
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1607326348
- Cited by
- 319
- References
- 2
- FWCI
- 6.99
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Gudas, L. J. (1994). Retinoids and vertebrate development. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(17)40689-2
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
