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Cited by 159Iron Metabolism and DisordersTrace Elements in HealthNeurological diseases and metabolism

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

Mobilization of liver iron by ferroxidase (ceruloplasmin).

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Osaki, Shigemasa, Johnson, Donald A.·1969·Journal of Biological Chemistry
DOI 10.1016/s0021-9258(18)63623-3
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Abstract

Abstract Iron was mobilized by human ferroxidase from dog liver into the perfusate under simulated physiological conditions. The rate of mobilization was estimated to be 1.8 µm per min per 4.9 µm ferroxidase. Human serum albumin with trace copper was found to be inactive in iron mobilization. The low Km and high k1 values of ferroxidase toward ferrous ion enabled us to deduce that the elimination of free iron in the perfusate by ferroxidase would generate a very steep concentration gradient between iron storage cells and the capillary system. This concentration gradient would promote a rapid iron out-flux from the cells by diffusion.

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Crossref · 10.1016/s0021-9258(18)63623-3

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11 of 11 references verified0 citation errors · 0 not checkable

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Citations

Cites

Research works printed but not linked: 1

  1. Ragan, H. A., Nacht, S., Leb, G. R., Bishop, C. R., and Cartwright, G. E., Amer. J. Physiol., in press.

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Metadata

Authors
Osaki, S., & Johnson, D. A.
Affiliations
Florida State University (US)
Venue
Journal of Biological Chemistry
Publisher
Elsevier BV
Published
1969-10
Volume
244
Issue
20
Pages
5757-5758
ISSN
0021-9258 (ISSN-L)
DOI
10.1016/s0021-9258(18)63623-3
OpenAlex
W1565446694
Cited by
159
References
11
Citations by year
2026: 1 · 2024: 4 · 2023: 1 · 2022: 1 · 2021: 1 · 2020: 2 · 2019: 2 · 2018: 2 · 2016: 2 · 2015: 5 · 2014: 7 · 2013: 7 · 2012: 3
FWCI
2.30
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Biological Chemistry (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Hematology › Iron Metabolism and Disorders
  • Health Sciences › Nursing › Nutrition and Dietetics › Trace Elements in Health
  • Life Sciences › Neuroscience › Neurology › Neurological diseases and metabolism
Keywords
ferroxidase, ceruloplasmin, liver iron, iron mobilization, ferrous iron oxidation, human serum albumin, copper, iron diffusion, canine liver
MeSH terms
Animals, Biological Transport, Ceruloplasmin, Dogs, Humans, Iron, Kinetics, Liver, Oxidoreductases, Perfusion, Serum Albumin, Spectrophotometry, Stimulation, Chemical, Time Factors, Transferrin, In Vitro Techniques

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