The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Alteration of Terminal Glycosylation Sequences on N-linked Oligosaccharides of Chinese Hamster Ovary Cells by Expression of β-Galactosideα2,6-Sialyltransferase
Open accessAbstract
In this report we describe the alteration of the N-linked oligosaccharide terminal sequences of Chinese hamster ovary cell glycoproteins by expression of a beta-galactoside alpha 2,6-sialyltransferase cDNA. While wild type cells normally produce sugar chains terminating in the NeuAc alpha 2,3Gal linkage, the expressed enzyme competes with the endogenous sialyltransferase to attach an alternative terminal sequence, NeuAc alpha 2,6Gal. Subcellular localization of the NeuAc alpha 2,6Gal product by lectin-gold electron microscopy revealed localization throughout the Golgi apparatus cis to trans, post-Golgi membranes and vesicular structures. The results demonstrate the potential for purposefully altering terminal carbohydrate structures in vivo by "mis-expressing" terminal glycosyltransferases that compete with the endogenous enzyme normally produced by the cells.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Ellis, L., Clauser, E., Morgan, D. O., Edery, M., Roth, R. A., & Rutter, W. J. (1986) · Cell · doi:10.1016/0092-8674(86)90786-5 · Cited by 1,070
Briles, E. B., Li, E., & Kornfeld, S. (1977) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)75213-2 · Cited by 220
Cited by
Paulson, J. C., & Colley, K. J. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)84610-0 · Cited by 909
Self-citationDavis, B. G. (2002) · Chemical Reviews · doi:10.1021/cr0004310 · Cited by 521
Getting the glycosylation right: Implications for the biotechnology industry
Jenkins, N., Parekh, R. B., & James, D. C. (1996) · Nature Biotechnology · doi:10.1038/nbt0896-975 · Cited by 458
High-sensitivity Analytical Approaches for the Structural Characterization of Glycoproteins
Alley, W. R., Mann, B. F., & Novotny, M. V. (2013) · Chemical Reviews · doi:10.1021/cr3003714 · Cited by 310
Munro, S. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb04924.x · Cited by 297
Metadata
- Authors
- Lee, E. U., Roth, J., & Paulson, J. C.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1989-08
- Volume
- 264
- Issue
- 23
- Pages
- 13848-13855
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1514815542
- Cited by
- 273
- References
- 2
- FWCI
- 5.21
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Alteration of Terminal Glycosylation Sequences on N-linked Oligosaccharides of Chinese Hamster Ovary Cells by Expression of β-Galactosideα2,6-Sialyltransferase. https://app.cochat.ai/papers/10.1016/s0021-9258(18)80078-3
- The paper
- Lee, E. U., Roth, J., & Paulson, J. C. (1989). Alteration of Terminal Glycosylation Sequences on N-linked Oligosaccharides of Chinese Hamster Ovary Cells by Expression of β-Galactosideα2,6-Sialyltransferase. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(18)80078-3
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
