The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Effects of two sec genes on protein assembly into the plasma membrane of Escherichia coli.
Open accessAbstract
We have examined the effects of thermosensitive mutations in secA and secY (prlA) genes on the export of proteins to the three layers of the Escherichia coli cell surface. After several hours at the nonpermissive temperature, the export of two major outer membrane proteins, lipoprotein and OmpA, is delayed, then essentially blocked, in either a secA or secY strain. These mutations also have a strong effect on the export of several proteins, such as maltose binding protein, to the periplasm, though the export of many periplasmic proteins is not affected. secA and secY block the assembly of leader peptidase, which is made without a leader sequence, into the inner membrane. However, the membrane assembly of M13 coat protein (an inner membrane protein made with an amino-terminal leader sequence) is not affected. Thus, the requirement for sec function for export does not correlate with the presence or absence of leader peptide or with a particular subcellular compartment, but rather is specific to each particular protein.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Randall, L. L. (1983) · Cell · doi:10.1016/0092-8674(83)90352-5 · Cited by 234
Cited by
Expert system for predicting protein localization sites in gram‐negative bacteria
Nakai, K., & Kanehisa, M. (1991) · Proteins: Structure, Function, and Bioinformatics · doi:10.1002/prot.340110203 · Cited by 746
vonHeijne, G. (1989) · Nature · doi:10.1038/341456a0 · Cited by 591
Brundage, L., Hendrick, J. P., Schiebel, E., Driessen, A. J. M., & Wickner, W. (1990) · Cell · doi:10.1016/0092-8674(90)90111-q · Cited by 505
Self-citationTranscending the impenetrable: How proteins come to terms with membranes
von Heijne, G. (1988) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(88)90013-5 · Cited by 466
ΔμH+ and ATP function at different steps of the catalytic cycle of preprotein translocase
Schiebel, E., Driessen, A. J. M., Hartl, F.-U., & Wickner, W. (1991) · Cell · doi:10.1016/0092-8674(91)90317-r · Cited by 458
Self-citation
Metadata
- Authors
- Wolfe, P. B., Rice, M., & Wickner, W.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1985-02
- Volume
- 260
- Issue
- 3
- Pages
- 1836-1841
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1550654653
- Cited by
- 217
- References
- 1
- FWCI
- 10.68
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Effects of two sec genes on protein assembly into the plasma membrane of Escherichia coli. https://app.cochat.ai/papers/10.1016/s0021-9258(18)89669-7
- The paper
- Wolfe, P. B., Rice, M., & Wickner, W. (1985). Effects of two sec genes on protein assembly into the plasma membrane of Escherichia coli. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(18)89669-7
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
