The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Misreading of Ribonucleic Acid Code Words Induced by Aminoglycoside Antibiotics
Open accessAbstract
Aminoglycoside antibiotics were found to vary widely in the effect of variation in their concentration on the degree of misreading of synthetic RNA messengers. Thus, neomycin, kanamycin, and gentamicin showed a 3- to 5-fold increase in the level of misreading as the drug concentration was raised from 10−6 to 10−4M. This effect suggests that each of these drugs may act on more than one site. Observed changes in the qualitative nature of the misreading at different concentrations support this inference, which is also consistent with the absence of one-step mutants with high level resistance to these drugs. In contrast, little increase in misreading, over the same concentration range, was seen with streptomycin and paromomycin, for which one-step, high level, resistant mutants are known. It therefore seems that these drugs each act on only a single site.
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Cites
STREPTOMYCIN, SUPPRESSION, AND THE CODE
Davies, J., Gilbert, W., & Gorini, L. (1964) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.51.5.883 · Cited by 474
Self-citationMisreading of RNA Codewords Induced by Aminoglycoside Antibiotics
DAVIES, J., GORINI, L., & DAVIS, B. D. (1965) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)14722-6 · Cited by 398
Self-citationDavies, J., Jones, D. S., & Khorana, H. G. (1966) · Journal of Molecular Biology · doi:10.1016/s0022-2836(66)80075-x · Cited by 145
Self-citationInhibition of Protein Synthesis by Spectinomycin
DAVIES, J. E., Anderson, P. W., & Davis, B. D. (1965) · Science · doi:10.1126/science.149.3688.1096 · Cited by 115
Self-citationBinding of dihydrostreptomycin to ribosomal subunits
Kaji, H. K., & Tanaka, Y. (1968) · Journal of Molecular Biology · doi:10.1016/0022-2836(68)90006-5 · Cited by 83
Studies on the Formation of Transfer Ribonucleic Acid-Ribosome Complexes
Pestka, S. (1966) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)96925-5 · Cited by 73
Effect of spectinomycin on polypeptide synthesis in extracts of Escherichia coli
Anderson, P. W., DAVIES, J. E., & Davis, B. D. (1967) · Journal of Molecular Biology · doi:10.1016/0022-2836(67)90191-x · Cited by 72
Self-citationEffect of streptomycin and neomycin on physical properties of the ribosome
Leon, S. A., & Brock, T. D. (1967) · Journal of Molecular Biology · doi:10.1016/0022-2836(67)90226-4 · Cited by 44
Cited by
Fourmy, D., Recht, M. I., Blanchard, S. C., & Puglisi, J. D. (1996) · Science · doi:10.1126/science.274.5291.1367 · Cited by 829
Mechanisms of Aminoglycoside Ototoxicity and Targets of Hair Cell Protection
Huth, M. E., Ricci, A. J., & Cheng, A. G. (2011) · International Journal of Otolaryngology · doi:10.1155/2011/937861 · Cited by 393
Fidelity at the Molecular Level: Lessons from Protein Synthesis
Zaher, H. S., & Green, R. (2009) · Cell · doi:10.1016/j.cell.2009.01.036 · Cited by 386
Antibiotic inhibitors of the bacterial ribosome
Weisblum, B., & Davies, J. (1968) · Bacteriological Reviews · doi:10.1128/br.32.4_pt_2.493-528.1968 · Cited by 318
Self-citationStark, H., Rodnina, M. V., Wieden, H.-J., van Heel, M., & Wintermeyer, W. (2000) · Cell · doi:10.1016/s0092-8674(00)80666-2 · Cited by 295
Metadata
- Authors
- Davies, J., & Davis, B. D.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1968-06
- Volume
- 243
- Issue
- 12
- Pages
- 3312-3316
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1552530238
- Cited by
- 269
- References
- 8
- FWCI
- 2.82
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Davies, J., & Davis, B. D. (1968). Misreading of Ribonucleic Acid Code Words Induced by Aminoglycoside Antibiotics. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(18)93308-9
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
