The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Stabilization of Adenylate Energy Charge by the Adenylate Deaminase Reaction
Open accessAbstract
Abstract In the physiological range of the adenylate energy charge in liver (0.7 to 0.9) the rate of deamination of AMP catalyzed by rat liver adenylate deaminase (EC 3.5.4.6) increases sharply with decreasing energy charge. It is suggested that this response serves to protect against sharp transient decreases in energy charge: when the charge decreases the resulting removal of AMP by deamination will oppose the decrease in charge (the mole fraction of ATP plus half the mole fraction of ADP). The activity of the enzyme decreases sharply as the size of the adenine nucleotide pool decreases in and below the physiological range. This effect may be a self-limiting response to prevent excessive depletion of the pool. These suggestions, based on the properties of the enzyme observed in vitro, are consistent with the results of experiments on liver in vivo reported by other workers.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers
Atkinson, D. E. (1968) · Biochemistry · doi:10.1021/bi00851a033 · Cited by 2,401
Self-citationDIFFERENTIAL SPECTROPHOTOMETRY OF PURINE COMPOUNDS BY MEANS OF SPECIFIC ENZYMES
Kalckar, H. M. (1947) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)30999-7 · Cited by 1,118
Adenylate Energy Charge in Escherichia coli During Growth and Starvation
Chapman, A. G., Fall, L., & Atkinson, D. E. (1971) · Journal of Bacteriology · doi:10.1128/jb.108.3.1072-1086.1971 · Cited by 779
Self-citationThe Regulation of Glycolysis and Gluconeogenesis in Animal Tissues
Scrutton, M. C., & Utter, M. F. (1968) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.37.070168.001341 · Cited by 631
The Concentrations of Free and Bound Magnesium in Rat Tissues
Veloso, D., Guynn, R. W., Oskarsson, M., & Veech, R. L. (1973) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)43738-1 · Cited by 383
Liver Adenine Nucleotides: Fructose-Induced Depletion and Its Effect on Protein Synthesis
Mäenpää, P. H., Raivio, K. O., & Kekomäki, M. P. (1968) · Science · doi:10.1126/science.161.3847.1253 · Cited by 343
Faupel, R. P., Seitz, H. J., Tarnowski, W., Thiemann, V., & Weiss, C. (1972) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(72)90170-1 · Cited by 209
Burch, H. B., Lowry, O. H., Meinhardt, L., Max, P., & Chyu, K.-J. (1970) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)63211-9 · Cited by 202
McComb, R. B., & Yushok, W. D. (1964) · PubMed · Cited by 66
Cited by
O’Brien III, W. G., Berka, V., Tsai, A.-L., Zhao, Z., & Lee, C. C. (2015) · Scientific Reports · doi:10.1038/srep13147 · Cited by 20
Metadata
- Authors
- Chapman, A. G., & Atkinson, D. E.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1973-12
- Volume
- 248
- Issue
- 23
- Pages
- 8309-8312
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1567446278
- Cited by
- 324
- References
- 9
- FWCI
- 4.42
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Stabilization of Adenylate Energy Charge by the Adenylate Deaminase Reaction. https://app.cochat.ai/papers/10.1016/s0021-9258(19)43229-8
- The paper
- Chapman, A. G., & Atkinson, D. E. (1973). Stabilization of Adenylate Energy Charge by the Adenylate Deaminase Reaction. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(19)43229-8
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
