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THE FUNCTION OF CYTIDINE COENZYMES IN THE BIOSYNTHESIS OF PHOSPHOLIPIDES
Open accessAbstract
In 1952, Kornberg and Pricer (1) reported in a preliminary communication that P-choline1 labeled with P32 and Cl* was converted by liver enzymes to a lipide which was not further characterized. The ratio of P32 to Cl4 in the product was closely similar to that of the labeled P-choline, suggesting incorporation of both phosphorus and choline as an intact unit into a phospholipide, presumably lecithin. The following reaction mechanism was suggested (2, 3) as a possible explanation for these results:
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Cited by
van der Veen, J. N., Kennelly, J. P., Wan, S., Vance, J. E., Vance, D. E., & Jacobs, R. L. (2017) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2017.04.006 · Cited by 1,514
Enzymes of triacylglycerol synthesis and their regulation
Coleman, R. (2004) · Progress in Lipid Research · doi:10.1016/s0163-7827(03)00051-1 · Cited by 965
Phospholipid Synthesis and Transport in Mammalian Cells
Vance, J. E. (2015) · Traffic · doi:10.1111/tra.12230 · Cited by 772
MAM (mitochondria-associated membranes) in mammalian cells: Lipids and beyond
Vance, J. E. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2013.11.014 · Cited by 625
Tumour phospholipid metabolism
Podo, F. (1999) · NMR in Biomedicine · doi:10.1002/(sici)1099-1492(199911)12:7<413::aid-nbm587>3.0.co;2-u · Cited by 579
Metadata
- Authors
- Kennedy, E. P., & Weiss, S. B.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1956-09
- Volume
- 222
- Issue
- 1
- Pages
- 193-214
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1575864823
- Cited by
- 1,810
- References
- 0
- FWCI
- 14.08
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- CoChat. (2026). Citation check: THE FUNCTION OF CYTIDINE COENZYMES IN THE BIOSYNTHESIS OF PHOSPHOLIPIDES. https://app.cochat.ai/papers/10.1016/s0021-9258(19)50785-2
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- Kennedy, E. P., & Weiss, S. B. (1956). THE FUNCTION OF CYTIDINE COENZYMES IN THE BIOSYNTHESIS OF PHOSPHOLIPIDES. Journal of Biological Chemistry. https://doi.org/10.1016/s0021-9258(19)50785-2
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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