Cooperative roles of various membrane phospholipids in the activation of calcium-activated, phospholipid-dependent protein kinase.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

Lowry, O. H., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 316,394

Inositol phospholipids and cell surface receptor function

Michell, R. H. (1975) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(75)90017-9 · Cited by 2,478

A simple method for the preparation of 32P-labelled adenosine triphosphate of high specific activity

Glynn, I. M., & Chappell, J. W. (1964) · Biochemical Journal · doi:10.1042/bj0900147 · Cited by 1,880

Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover.

Kishimoto, A., Takai, Y., Terutoshi, M. O. R. I., Kikkawa, U., & Nishizuka, Y. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)85886-6 · Cited by 1,303

Lipid Asymmetry in Membranes

den Kamp, J. A. F. O. (1979) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.48.070179.000403 · Cited by 1,262

Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids.

Takai, Y., Kishimoto, A., Iwasa, Y., Kawahara, Y., Terutoshi, M. O. R. I., & Nishizuka, Y. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50638-4 · Cited by 1,138

Phospholipid Methylation and Biological Signal Transmission

Hirata, F., & Axelrod, J. (1980) · Science · doi:10.1126/science.6157192 · Cited by 1,100

Membrane Asymmetry

Rothman, J. E., & Lenard, J. (1977) · Science · doi:10.1126/science.402030 · Cited by 987

Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain.

Inoue, M., Kishimoto, A., Takai, Y., & Nishizuka, Y. (1977) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)41010-6 · Cited by 863

Unsaturated diacylglycerol as a possible messenger for the activation of calcium-activated, phospholipid-dependent protein kinase system

Takai, Y., Kishimoto, A., Kikkawa, U., Terutoshi, M. O. R. I., & Nishizuka, Y. (1979) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(79)91197-5 · Cited by 731

The role of protein kinase C in cell surface signal transduction and tumour promotion

Nishizuka, Y. (1984) · Nature · doi:10.1038/308693a0 · Cited by 7,455

Studies and Perspectives of Protein Kinase C

Nishizuka, Y. (1986) · Science · doi:10.1126/science.3014651 · Cited by 5,068

Direct activation of calcium‐activated, phospholipid‐dependent protein kinase by tumor‐promoting phorbol esters

Castagna, M., Takai, Y., Kaibuchi, K., Sano, K., Kikkawa, U., & Nishizuka, Y. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)34459-4 · Cited by 4,725

Turnover of Inositol Phospholipids and Signal Transduction

Nishizuka, Y. (1984) · Science · doi:10.1126/science.6147898 · Cited by 1,614

Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.

Hannun, Y. A., Loomis, C. R., Merrill, A. H., & Bell, R. M. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67133-9 · Cited by 1,156

Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties.

Kikkawa, U., Takai, Y., Minakuchi, R., Inohara, S., & Nishizuka, Y. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)33453-7 · Cited by 1,003

Protein kinase C as a possible receptor protein of tumor‐promoting phorbol esters

Kikkawa, U., Takai, Y., Tanaka, Y., Miyake, R., & Nishizuka, Y. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)44245-1 · Cited by 881

Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation.

Kaibuchi, K., Takai, Y., Sawamura, M., Hoshijima, M., Fujikura, T., & Nishizuka, Y. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)32273-7 · Cited by 694

Diacylglycerol and phorbol ester stimulate secretion without raising cytoplasmic free calcium in human platelets

RINK, T. J., Sánchez, A., & Hallam, T. J. (1983) · Nature · doi:10.1038/305317a0 · Cited by 586

Angiotensin II-stimulated protein synthesis in cultured vascular smooth muscle cells.

Berk, B. C., Vekshtein, V. I., Gordon, H. M., & Tsuda, T. (1989) · Hypertension · doi:10.1161/01.hyp.13.4.305 · Cited by 555

Lipid activation of protein kinase C.

Bell, R. M., & Burns, D. J. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)67698-2 · Cited by 555

Decrease in cytosolic calcium/phospholipid-dependent protein kinase activity following phorbol ester treatment of EL4 thymoma cells.

Kraft, A. S., Anderson, W. B., Cooper, H. L., & Sando, J. J. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)33427-6 · Cited by 412

Epidermal growth factor and potent phorbol tumor promoters induce epidermal growth factor receptor phosphorylation in a similar but distinctively different manner in human epidermoid carcinoma A431 cells.

Iwashita, S., & Fox, C. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)43390-4 · Cited by 326

Phospholipid degradation and signal translation for protein phosphorylation

Nishizuka, Y. (1983) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(83)90061-0 · Cited by 319

Competitive inhibition by diacylglycerol of specific phorbol ester binding.

Sharkey, N. A., Leach, K. L., & Blumberg, P. M. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.2.607 · Cited by 306

Molecular Events Mediating T Cell Activation

Altman, A., Coggeshall, K. M., & Mustelin, T. (1990) · Advances in immunology · doi:10.1016/s0065-2776(08)60756-7 · Cited by 291

Direct activation of purified protein kinase C by unsaturated fatty acids (oleate and arachidonate) in the absence of phospholipids and Ca2+

Murakami, K., & Routtenberg, A. (1985) · FEBS Letters · doi:10.1016/0014-5793(85)80105-8 · Cited by 290

Purification and characterization of the zeta isoform of protein kinase C from bovine kidney.

Nakanishi, H., & Exton, J. H. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42008-x · Cited by 281

Purification to homogeneity of protein kinase C from bovine brain–identity with the phorbol ester receptor.

Parker, P. J., Stabel, S., & Waterfield, M. D. (1984) · The EMBO Journal · doi:10.1002/j.1460-2075.1984.tb01913.x · Cited by 281

[31] Calcium-activated, phospholipid-dependent protein kinase (protein kinase C) from rat brain

Kikkawa, U., Minakuchi, R., Takai, Y., & Nishizuka, Y. (1983) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(83)99064-x · Cited by 275

Protein kinase C: a paradigm for regulation of protein function by two membrane-targeting modules.

Newton, A., & Johnson, J. E. (1998) · Biochimica et Biophysica Acta · doi:10.1016/s0304-4157(98)00003-3 · Cited by 276

Insulin secretion: Combined effects of phorbol ester and A23187

Zawalich, W. S., Brown, C. R., & Rasmussen, H. (1983) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(83)91221-4 · Cited by 250

The nature of protein kinase C activation by physically defined phospholipid vesicles and diacylglycerols.

Boni, L. T., & Rando, R. R. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)85156-6 · Cited by 232

The role of phosphoinositiees in signal transduction

Sekar, M. C., & Hokin, L. E. (1986) · The Journal of Membrane Biology · doi:10.1007/bf01870664 · Cited by 227

Expression, purification, and characterization of protein kinase C-epsilon.

Schaap, D., & Parker, P. J. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)39114-8 · Cited by 227

Protein kinase C activation in mixed micelles. Mechanistic implications of phospholipid, diacylglycerol, and calcium interdependencies.

Hannun, Y. A., Loomis, C. R., & Bell, R. M. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)38372-2 · Cited by 215

Phospholipid-sensitive Ca2+-dependent protein phosphorylation system in various types of leukemic cells from human patients and in human leukemic cell lines HL60 and K562, and its inhibition by alkyl-lysophospholipid.

Helfman, D. M., Barnes, K. C., Kinkade, J. M., Vogler, W. R., Shoji, M., & Kuo, J. F. (1983) · PubMed · Cited by 208

Mechanism of action of the phorbol ester tumor promoters: Specific receptors for lipophilic ligands

Blumberg, P. M., Jaken, S., König, B., Sharkey, N. A., Leach, K. L., Jeng, A. Y., & Yeh, E. (1984) · Biochemical Pharmacology · doi:10.1016/0006-2952(84)90448-9 · Cited by 205

Affinity chromatography of protein kinase C-phorbol ester receptor on polyacrylamide-immobilized phosphatidylserine.

Uchida, T., & Filburn, C. R. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)90743-x · Cited by 203

T‐Lymphocyte Activation: The Role of Protein Kinase C and the Bifurcating Inositol Phospholipid Signal Transduction Pathway

Isakov, N., Mally, M. I., Scholz, W. W., & Altman, A. (1987) · Immunological Reviews · doi:10.1111/j.1600-065x.1987.tb00501.x · Cited by 202

Signal transduction in macrophages by glycosylphosphatidylinositols of Plasmodium , Trypanosoma , and Leishmania : Activation of protein tyrosine kinases and protein kinase C by inositolglycan and diacylglycerol moieties

Tachado, S. D., Gerold, P., Schwarz, R. Τ., Novakovic, S., McConville, M. J., & Schofield, L. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.8.4022 · Cited by 195

Phosphatidylinositol turnover in platelet activation; Calcium mobilization and protein phosphorylation

Kaibuchi, K., Sano, K., Hoshijima, M., Takai, Y., & Nishizuka, Y. (1982) · Cell Calcium · doi:10.1016/0143-4160(82)90020-3 · Cited by 195

Phosphorylation, high ionic strength, and calmodulin reverse the binding of MARCKS to phospholipid vesicles.

Kim, J., Shishido, T., Jiang, X., Aderem, A. A., & McLaughlin, S. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)46916-5 · Cited by 186

Nerve growth cones isolated from fetal rat brain. III. Calcium- dependent protein phosphorylation

Katz, F. N., Ellis, L., & Pfenninger, K. H. (1985) · Journal of Neuroscience · doi:10.1523/jneurosci.05-06-01402.1985 · Cited by 183

Mechanisms of hormonal regulation of hepatic glucose metabolism

Exton, J. H. (1987) · Diabetes/Metabolism Reviews · doi:10.1002/dmr.5610030108 · Cited by 178

Phospholipid Turnover in Hormone Action

Nishizuka, Y., Takai, Y., Kishimoto, A., Kikkawa, U., & Kaibuchi, K. (1984) · Elsevier eBooks · doi:10.1016/b978-0-12-571140-1.50012-8 · Cited by 174

The modulation of protein kinase C activity by membrane lipid bilayer structure.

Slater, S. J., Kelly, M. B., Taddeo, F. J., Ho, C., Rubin, E., & Stubbs, C. D. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)37624-x · Cited by 166

[24] Assay and purification of protein kinase C

Kitano, T., Go, M., Kikkawa, U., & Nishizuka, Y. (1986) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(86)24026-4 · Cited by 160

Phosphorylation reverses the membrane association of peptides that correspond to the basic domains of MARCKS and neuromodulin

Kim, J., Blackshear, P. J., Johnson, J. D., & McLaughlin, S. (1994) · Biophysical Journal · doi:10.1016/s0006-3495(94)80473-4 · Cited by 154

Sangivamycin, a nucleoside analogue, is a potent inhibitor of protein kinase C.

Loomis, C. R., & Bell, R. M. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)77930-7 · Cited by 155

Identification of high-affinity phorbol ester receptor in cytosol of EL4 thymoma cells: requirement for calcium, magnesium, and phospholipids.

Sando, J. J., & Young, M. C. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.9.2642 · Cited by 155

Isolation of cDNA clones encoding protein kinase C: evidence for a protein kinase C-related gene family.

Housey, G. M., O'Brian, C. A., Johnson, M. D., Kirschmeier, P. T., & Weinstein, I. B. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.4.1065 · Cited by 151

Association of protein kinase C with phospholipid vesicles

Bazzi, M. D., & Nelsestuen, G. L. (1987) · Biochemistry · doi:10.1021/bi00375a017 · Cited by 150

Phosphatidate-dependent protein phosphorylation.

Bocckino, S. B., Wilson, P. B., & Exton, J. H. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.14.6210 · Cited by 150

The C1 and C2 Domains of Protein Kinase C Are Independent Membrane Targeting Modules, with Specificity for Phosphatidylserine Conferred by the C1 Domain

Johnson, J. E., Giorgione, J. R., & Newton, A. C. (2000) · Biochemistry · doi:10.1021/bi000902c · Cited by 148

G protein-coupled receptor kinases as therapeutic targets in the heart

Pfleger, J. M., Gresham, K. S., & Koch, W. J. (2019) · Nature Reviews Cardiology · doi:10.1038/s41569-019-0220-3 · Cited by 154

Agents that activate protein kinase C reduce acetylcholine sensitivity in cultured myotubes.

Eusebi, F., Molinaro, M., & ZANI, B. M. (1985) · The Journal of Cell Biology · doi:10.1083/jcb.100.4.1339 · Cited by 142

Thyrotropin-releasing hormone induces redistribution of protein kinase C in GH4C1 rat pituitary cells.

Fearon, C. W., & Tashjian, A. H. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)39482-6 · Cited by 140

The stereospecific activation of protein kinase C

Rando, R. R., & Young, N. D. (1984) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(84)80107-2 · Cited by 137

Diacylglycerol kinase from pig brain. Purification and phospholipid dependencies.

Kanoh, H., Kondoh, H., & Ono, T. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)33053-9 · Cited by 135

Mechanisms involved in alpha-adrenergic phenomena

Exton, J. H. (1985) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1985.248.6.e633 · Cited by 129

A possible role of protein kinase C in signal-induced lysosomal enzyme release

Kajikawa, N., Kaibuchi, K., Matsubara, T., Kikkawa, U., Takai, Y., Nishizuka, Y., Itoh, K., & Tomioka, C. (1983) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(83)90587-9 · Cited by 129

Direct Activation of Protein Kinase C by 1α,25-Dihydroxyvitamin D3

Slater, S. J., Kelly, M. B., Taddeo, F. J., Larkin, J. D., Yeager, M. D., McLane, J. A., Ho, C., & Stubbs, C. D. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.12.6639 · Cited by 127

Stimulus specificity of prostaglandin inhibition of rabbit polymorphonuclear leukocyte lysosomal enzyme release and superoxide anion production.

Fantone, J. C., Marasco, W. A., Elgas, L. J., & Ward, P. A. (1984) · PubMed Central · Cited by 123

Phospholipid-sensitive Ca2+-dependent protein kinase: a major protein phosphorylation system

Kuo, J. F., Schatzman, R. C., Turner, R. S., & Mazzei, G. J. (1984) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(84)90001-7 · Cited by 121

The role of phospholipid-derived mediators including arachidonic acid, its metabolites, and inositol triphosphate and of intracellular Ca2+ in glucose-induced insulin secretion by pancretic islets

TURK, J. W. (1987) · Progress in Lipid Research · doi:10.1016/0163-7827(87)90010-5 · Cited by 117

High Cooperativity, Specificity, and Multiplicity in the Protein Kinase C-Lipid Interaction

Newton, A. C., & Koshland, D. E. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)63788-3 · Cited by 118

Phospholipid Functional Groups Involved in Protein Kinase C Activation, Phorbol Ester Binding, and Binding to Mixed Micelles

Lee, M. H., & Bell, R. M. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)63770-6 · Cited by 114

The onset of the respiratory burst in human neutrophils. Real-time studies of H2O2 formation reveal a rapid agonist-induced transduction process.

Wymann, M. P., von Tscharner, V., Deranleau, D. A., & Baggiolini, M. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)45315-x · Cited by 114

Phosphorylation of cardiac sarcolemma proteins by the calcium-activated phospholipid-dependent protein kinase.

Iwasa, Y., & Hosey, M. M. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)43694-5 · Cited by 113

Guanine-nucleotide and hormone regulation of polyphosphoinositide phospholipase C activity of rat liver plasma membranes. Bivalent-cation and phospholipid requirements

Taylor, S. J., & Exton, J. H. (1987) · Biochemical Journal · doi:10.1042/bj2480791 · Cited by 113

Phosphorylation of the? subunit of the sodium channel by protein kinase C

Costa, M. R. C., & Catterall, W. A. (1984) · Cellular and Molecular Neurobiology · doi:10.1007/bf00733592 · Cited by 111

Regulation of a ribosomal protein S6 kinase activity by the Rous sarcoma virus transforming protein, serum, or phorbol ester.

Blenis, J., & Erikson, R. L. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.22.7621 · Cited by 111

A phorbol ester binding domain of protein kinase C gamma. Deletion analysis of the Cys2 domain defines a minimal 43-amino acid peptide.

Quest, A. F. G., Bardes, E. S. G., & Bell, R. M. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)42034-5 · Cited by 105

On the molecular-level mechanisms of peripheral protein-membrane interactions induced by lipids forming inverted non-lamellar phases

Kinnunen, P. K. J. (1996) · Chemistry and Physics of Lipids · doi:10.1016/0009-3084(96)02579-0 · Cited by 103

Modes of inhibition by acylcarnitines, adriamycin and trifluoperazine of cardiac phospholipid-sensitive calcium-dependent protein kinase

Wise, B. C., & Kuo, J. F. (1983) · Biochemical Pharmacology · doi:10.1016/0006-2952(83)90280-0 · Cited by 101

The effect of phosphatidylserine containing Omega3 fatty-acids on attention-deficit hyperactivity disorder symptoms in children: A double-blind placebo-controlled trial, followed by an open-label extension

Manor, I., Magen, A., Keidar, D., Rosen, S., Tasker, H., Cohen, T., Richter, Y., Zaaroor-Regev, D., Manor, Y., & Weizman, A. (2012) · European psychiatry · doi:10.1016/j.eurpsy.2011.05.004 · Cited by 98

Identification of a calcium‐ and phospholipid‐dependent protein kinase in plant tissue

Schäfer, A., Bygrave, F. L., Matzenauer, S., & Marmé, D. (1985) · FEBS Letters · doi:10.1016/0014-5793(85)81206-0 · Cited by 100

Identification of an endogenous protein kinase C activity and its intrinsic 15-kilodalton substrate in purified canine cardiac sarcolemmal vesicles.

Presti, C. F., Scott, B., & Jones, L. R. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)38806-3 · Cited by 99

Role of phosphoinositides in the regulation of liver function

Exton, J. H. (1988) · Hepatology · doi:10.1002/hep.1840080129 · Cited by 99

Importance of phosphatidylethanolamine for association of protein kinase C and other cytoplasmic proteins with membranes

Bazzi, M. D., Youakim, M. A., & Nelsestuen, G. L. (1992) · Biochemistry · doi:10.1021/bi00119a022 · Cited by 98

Role of the Enzyme Calmodulin-binding Domain in Membrane Association and Phospholipid Inhibition of Endothelial Nitric Oxide Synthase

Venema, R. C., Sayegh, H. S., Arnal, J., & Harrison, D. G. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.24.14705 · Cited by 96

Diacylglycerol activation of protein kinase C is modulated by long-chain acyl-CoA

Bronfman, M., Morales, M. N., & Orellana, A. (1988) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(88)80381-4 · Cited by 95

Purification to homogeneity, characterization and monoclonal antibodies of phospholipid-sensitive Ca2+-dependent protein kinase from spleen

Schatzman, R. C., Raynor, R. L., Fritz, R. B., & Kuo, J. F. (1983) · Biochemical Journal · doi:10.1042/bj2090435 · Cited by 94

Electrostatics of phosphoinositide bilayer membranes. Theoretical and experimental results

Langner, M., Cafiso, D. S., Marĉelja, S., & McLaughlin, S. (1990) · Biophysical Journal · doi:10.1016/s0006-3495(90)82535-2 · Cited by 93

Interaction of protein kinase C with phosphatidylserine. 1. Cooperativity in lipid binding

Orr, J. W., & Newton, A. C. (1992) · Biochemistry · doi:10.1021/bi00134a018 · Cited by 93

Modulation of protein kinase C activity and [3H]phorbol 12,13-dibutyrate binding by various tumor promoters in mouse brain cytosol.

Leach, K. L., & Blumberg, P. M. (1985) · PubMed · Cited by 89

The epithelial/carcinoma antigen EGP‐1, recognized by monoclonal antibody RS7–3G11, is phosphorylated on serine 303

Basu, A., Goldenberg, D. M., & Stein, R. (1995) · International Journal of Cancer · doi:10.1002/ijc.2910620419 · Cited by 88

Mechanism of activation of protein kinase C: roles of diolein and phosphatidylserine

Mosior, M. K., & Epand, R. M. (1993) · Biochemistry · doi:10.1021/bi00052a010 · Cited by 88

Conductance changes underlying a late synaptic hyperpolarization in hippocampal CA3 neurons

Hablitz, J. J., & Thalmann, R. H. (1987) · Journal of Neurophysiology · doi:10.1152/jn.1987.58.1.160 · Cited by 88

Characterization of cytosolic calcium-activated phospholipid-dependent protein kinase activity in embryonal carcinoma cells. Effect of retinoc acid-induced differentiation of F9 cells to parietal endoderm.

Kraft, A. S., & Anderson, W. B. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)44648-5 · Cited by 87

The effect of phosphatidylserine administration on memory and symptoms of attention‐deficit hyperactivity disorder: a randomised, double‐blind, placebo‐controlled clinical trial

Hirayama, S., TERASAWA, K., Rabeler, R., Hirayama, T., Inoue, T., 辰巳, 泰., Purpura, M., & Jäger, R. (2013) · Journal of Human Nutrition and Dietetics · doi:10.1111/jhn.12090 · Cited by 90

Protein kinase C autophosphorylates by an intrapeptide reaction.

Newton, A. C., & Koshland, D. E. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)61095-6 · Cited by 83

Determination of the phase behaviour of phosphatidylethanolamine admixed with other lipids and the effects of calcium chloride: implications for protein kinase C regulation

Epand, R. M., & Bottega, R. (1988) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(88)90427-0 · Cited by 82

Transbilayer inhibition of protein kinase C by the lipophosphoglycan from Leishmania donovani.

Giorgione, J. R., Turco, S. J., & Epand, R. M. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.21.11634 · Cited by 80

Role of protein kinase C in transmembrane signaling

Takai, Y., Kaibuchi, K., Tsuda, T., & Hoshijima, M. (1985) · Journal of Cellular Biochemistry · doi:10.1002/jcb.240290209 · Cited by 79

Characterization of protein kinase C and its role in catecholamine secretion from bovine adrenal-medullary cells

Brocklehurst, K., Morita, K., & Pollard, H. B. (1985) · Biochemical Journal · doi:10.1042/bj2280035 · Cited by 79

Intracellular Mediators of Insulin Action

Cheng, K., & Larner, J. (1985) · Annual Review of Physiology · doi:10.1146/annurev.ph.47.030185.002201 · Cited by 78

Phosphatidic acid and phosphatidylinositol labelling in adipose tissue. Relationship to the metabolic effects of insulin and insulin-like agents

Honeyman, T. W., Strohsnitter, W. C., Scheid, C. R., & Schimmel, R. J. (1983) · Biochemical Journal · doi:10.1042/bj2120489 · Cited by 76

Infrared spectroscopic study of the interaction of diacylglycerol with phosphatidylserine in the presence of calcium

López-García, F., Micol, V., Villalaı́n, J., & Gómez-Fernández, J. C. (1993) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(93)90250-d · Cited by 74

Effects of sphingosine, albumin and unsaturated fatty acids on the activation and translocation of phosphatidate phosphohydrolases in rat hepatocytes

Gómez‐Muñoz, A., Hamza, E., & Brindley, D. N. (1992) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(92)90200-f · Cited by 71

Role of phospholipids containing docosahexaenoyl chains in modulating the activity of protein kinase C.

Giorgione, J. R., Epand, R. M., Buda, C., & Farkas, T. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.21.9767 · Cited by 71

Phosphorylation of a chromaffin granule-binding protein by protein kinase C.

Summers, T. A., & Creutz, C. E. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)89573-4 · Cited by 71

Pathways signaling the regulatory volume decrease of cultured nonpigmented ciliary epithelial cells.

Civan, M. M., Coca‐Prados, M., & Peterson–Yantorno, K. (1994) · PubMed · Cited by 71

Evidence for discrete diacylglycerol and phorbol ester activator sites on protein kinase C. Differences in effects of 1-alkanol inhibition, activation by phosphatidylethanolamine and calcium chelation.

Slater, S. J., Kelly, M. B., Taddeo, F. J., Rubin, E., & Stubbs, C. D. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)32535-8 · Cited by 68

Association of protein kinase C with phospholipid monolayers: two-stage irreversible binding

Bazzi, M. D., & Nelsestuen, G. L. (1988) · Biochemistry · doi:10.1021/bi00418a020 · Cited by 68

Protein kinase C activation during progesterone-stimulated acrosomal exocytosis in human spermatozoa

Toole, C. M. B. O., Roldán, E. R. S., & Fraser, L. R. (1996) · Molecular Human Reproduction · doi:10.1093/molehr/2.12.921 · Cited by 66

The use of FT-IR for quantitative studies of the apparent pKa of lipid carboxyl groups and the dehydration degree of the phosphate group of phospholipids

Gómez-Fernández, J. C., & Villalaı́n, J. (1998) · Chemistry and Physics of Lipids · doi:10.1016/s0009-3084(98)00079-6 · Cited by 66

Dendritic spine loss in hippocampus of aged rats. Effect of brain phosphatidylserine administration

Nunzi, M. G., Milán, F. J., Guidolin, D., & Toffano, G. (1987) · Neurobiology of Aging · doi:10.1016/0197-4580(87)90124-2 · Cited by 65

Activation of protein kinase C in neutrophil cytoplasts

Gennaro, R., Florio, C., & Romeo, D. (1985) · FEBS Letters · doi:10.1016/0014-5793(85)81068-1 · Cited by 66

A new possible regulatory system for protein phosphorylation in human peripheral lymphocytes. II. Possible relation to phosphatidylinositol turnover induced by mitogens.

Ku, Y., Kishimoto, A., Takai, Y., Ogawa, Y., Kimura, S., & Nishizuka, Y. (1981) · The Journal of Immunology · doi:10.4049/jimmunol.127.4.1375 · Cited by 58

Phospholipid-dependence of rat liver plasma membrane protein kinase activities — a new approach

Gavrilova, N. J., Markovska, T. T., Momchilova, A., Setchenska, M. S., & Koumanov, K. S. (1992) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(92)90211-4 · Cited by 15

Lipid-dependent membrane enzymes. Kinetic modelling of the activation of protein kinase C by phosphatidylserine

Sandermann, H., & Duncan, T. M. (1991) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(91)90130-z · Cited by 12

The role of hydrophobic interactions in the phospholipid-dependent activation of protein kinase C.

Snoek, G. T., Feijen, A., Hage, W. J., van Rotterdam, W., & de Laat, S. W. (1988) · PubMed Central · Cited by 37

Supplementation of the phosphatidyl-L-serine requirement of protein kinase C with nonactivating phospholipids

Lee, M. H., & Bell, R. M. (1992) · Biochemistry · doi:10.1021/bi00137a013 · Cited by 29